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Cytogenomics   Research Article

Structural and functional characterization of the Colletotrichum lindemuthianum nit1 gene, which encodes a nitrate eductase enzyme

Authors: G.B. Nogueira M.V. Queiroz R.A. Ribeiro E.F. Ara�ºjo

Colletotrichum lindemuthianum is the causal agent of plant bean anthracnose, one of the most important diseases affecting the common bean. We investigated the structure and expression of the nit1 gene (nitrate reductase) of C. lindemuthianum. The nit1 gene open reading frame contains 2787 bp, interrupted by a single 69-bp intron. The predicted protein has 90.. Read More»

Genet. Mol. Res. 12(1):
2013.February.8.7
DOI:
10.4238/2013.February.8.7
Plant Genetics   Letter to the Editor

Partial diallel crosses for predicting yield of semiexotic maize populations

Authors: C.M. Silva, J.B. Miranda Filho, U.C. Mendes and E.F. Reis

In Brazil, the total production of maize has increased continuously due to the advances in technology but also to the new frontiers for the maize crop, including the expansion of the second crop (safrinha; usually maize after soybean). Therefore, the exploitation of new sources of germplasm seems to be imperative to attend the.. Read More»

Genet. Mol. Res. 16(1):
gmr16019544
DOI:
10.4238/gmr16019544
Microbial Genetics   Research Article

Microbiological quality and bacterial diversity of the tropical oyster Crassostrea rhizophorae in a monitored farming system and from natural stocks

Authors: M.T. Silva Neta, B.M. Maciel, A.T.S. Lopes, E.L.S. Marques,R.P. Rezende, G. Boehs

Microbiological evaluation is one of the most important parameters for analyzing the viability of an oyster farming system, which addresses public health and ecological concerns. Here, the microbiological quality of the oyster Crassostrea rhizophorae cultivated in a monitored environment and from natural beds in Bahia, northea.. Read More»

Genet. Mol. Res. 14(4):
2015.December.1.27
DOI:
10.4238/2015.December.1.27
Human Genetics   Research Article

Roles of peripheral B1 cells in the individualized treatment of adult idiopathic thrombocytopenic purpura

Authors: H.-Q. Luo, Y.-G. Zhong, G.-Z. Zhou, J.-P. Fu and W.-Y. Feng

The aim of this study was to perform an association study between seven Fyn-binding protein gene (FYB)-tag single nucleotide polymorphisms (SNPs) and type I diabetes mellitus (T1DM), as well as with disease age of onset. We also assessed the role of FYB SNPs in the insurgence of autoimmune polyglandular syndrome type III (APSIII), characterized by the sim.. Read More»

Genet. Mol. Res. 14(1):
2015.January.15.3
DOI:
10.4238/2015.January.15.3
Human Genetics   Research Article

Meta-analysis demonstrates association of the TGF-�²1 gene -C509T polymorphism with susceptibility to IgA nephropathy in European but not in Asian populations

Authors: H. Wang P. Li Z.-C. Feng

There are conflicting reports associating the TGF-β1 gene -C509T polymorphism with susceptibility to IgA nephropathy. We investigated this association through a meta-analysis. Case-control studies were searched up to January 2012; the genotype frequencies in the control group were found to be consistent with Hardy-Weinberg equilibrium. Publication bi.. Read More»

Genet. Mol. Res. 12(1):
2013.February.8.8
DOI:
10.4238/2013.February.8.8
Microbial Genetics   Research Article

Multivariate approach in popcorn genotypes using the Ward-MLM strategy: morpho-agronomic analysis and incidence of Fusarium spp

Authors: R.N.F. Kurosawa, A.T. do Amaral Junior, F.H.L. Silva, A. dos Santos,M. Vivas, S.H. Kamphorst and G.F. Pena

The multivariate analyses are useful tools to estimate the genetic variability between accessions. In the breeding programs, the Ward-Modified Location Model (MLM) multivariate method has been a powerful strategy to quantify variability using quantitative and qualitative variables simultaneously. The present study was proposed.. Read More»

Genet. Mol. Res. 16(1):
gmr16019528
DOI:
10.4238/gmr16019528
Human Genetics   Research Article

FYB polymorphisms in Brazilian patients with type I diabetes mellitus and autoimmune polyglandular syndrome type III

Authors: C.J.C. Addobbati, J. de Azev�ªdo Silva, N.A.C. Tavares, J. Ara�ºjo, R.L. Guimar�£es, L. Brand�£o, S. Crovella and P. Sandrin-Garcia

The present study investigates the effects of electroacupuncture (EA) on urinary bladder pressure (UBP) in patients with acute gastrointestinal injury (AGI). Twenty patients with AGI admitted to the First Hospital of Jiaxing intensive care unit from December 2011 to June 2013 were evaluated. Conventional group patients (n = 10) were administered moderate .. Read More»

Genet. Mol. Res. 14(1):
2015.January.15.4
DOI:
10.4238/2015.January.15.4
Human Genetics   Research Article

Dihydromyricetin induces cell apoptosis via a p53-related pathway in AGS human gastric cancer cells

Authors: F.J. Ji, X.F. Tian, X.W. Liu, L.B. Fu, Y.Y. Wu, X.D. Fang,H.Y. Jin

The aim of the present study was to determine the anti­proliferative and pro-apoptotic effects of dihydromyricetin (DHM) on the AGS human gastric cancer cells and their underlying mechanisms. The effects of DHM on AGS cells were evaluated by using 3-(4, 5-di­methylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT), la.. Read More»

Genet. Mol. Res. 14(4):
2015.December.1.7
DOI:
10.4238/2015.December.1.7
Human Genetics   Review Article

Genetic tests for low- and middle-income countries: a literature review

Authors: P.E. Maltese, E. Poplavskaia, I. Malyutkina, F. Sirocco, A. Bonizzato, N. Capodicasa, S.Y. Nicoulina, A. Salmina, N. Aksutina, M. Dundar, T. Beccari, S. Cecchin and M. Bertelli

The aim of this review is to describe a series of ten genetic diseases with Mendelian inheritance pattern in people of low- or middle-income countries, which can be easily identified with simple and affordable methods. Recent information shows that although genetic diseases account for more than 10% of infant mortality in such.. Read More»

Genet. Mol. Res. 16(1):
gmr16019466
DOI:
10.4238/gmr16019466
Plant Genetics   Research Article

Distribution of mating-type alleles and M13 PCR markers in the black leaf spot fungus Mycosphaerella fijiensis of bananas in Brazil

Authors: C.B. Queiroz E.C. Miranda R.E. Hanada N.R. Sousa L. Gasparotto M.A. Soares G.F. Silva

The fungus Mycosphaerella fijiensis is the causative agent of black sigatoka, which is one of the most destructive diseases of banana plants. Infection with this pathogen results in underdeveloped fruit, with no commercial value. We analyzed the distribution of the M. fijiensis mating-type system and its genetic variability using M13 phage DNA markers. We fo.. Read More»

Genet. Mol. Res. 12(1):
2013.February.8.9
DOI:
10.4238/2013.February.8.9