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Human Genetics   Research Article

VDAC2 involvement in the stress response pathway in Arabidopsis thaliana

Authors: Z. Liu, Q.H. Luo, G.Q. Wen, J.M. Wang, X.F. Li,Y. Yang

The voltage-dependent anion channel (VDAC) is the major transport protein in the outer membrane of mitochondria, and is involved in the formation of a permeable transition pore and metabolite transport. In this study, we explored the role of Arabidopsis thaliana VDAC2 (AtVDAC2) in the signal transduction pathway in Arabidopsis.. Read More»

Genet. Mol. Res. 14(4):
2015.December.1.1
DOI:
10.4238/2015.December.1.1
Plant Genetics   Research Article

Case of escape in cassava, Manihot esculenta Crantz

Authors: N.M.A. Nassar and M. Mendonza

Two cassava escapes where collected from cultivated fields near natural habitat in Bolivia. They are described morphologically and analyzed cytogenetically in this study. It is suggested that they are the product of backcrosses of cassava interspecific hybrids with the cultigen itself, and that selective conditions have develo.. Read More»

Genet. Mol. Res. 16(1):
gmr16019577
DOI:
10.4238/gmr16019577
Human Genetics   Research Article

A study of the association between the connexin 40 rs35594137 polymorphism and atrial fibrillation in Xinjiang Chinese Han and Uygur populations

Authors: Y. Feng, J. Sun, L. Wang, X.L. Hou

Atrial fibrillation (AF) occurrence has a known genetic component. Many reports have revealed a correlation between gene mutation and AF, involving genes related to ion channels, connexin (Cx), and those within the angiotensin system. In this study, the cor­relation between the Cx 40 polymorphism (rs35594137) and AF was in.. Read More»

Genet. Mol. Res. 14(4):
2015.December.1.22
DOI:
10.4238/2015.December.1.22
Animal Genetics   Research Article

Genetic diversity and differentiation in natural populations of Arapaima gigas from lower Amazon revealed by microsatellites

Authors: P.F. Fazzi-Gomes, N. Melo, G. Palheta, S. Guerreiro, M. Amador, A.K. Ribeiro-dos-Santos, S. Santos and I. Hamoy

Genetic variability is one of the important criteria for species conservation decisions. This study aimed to analyze the genetic diversity and the population differentiation of two natural populations of Arapaima gigas, a species with a long history of being commercially exploited. We collected 87 samples of A. gigas from Gran.. Read More»

Genet. Mol. Res. 16(1):
gmr16019552
DOI:
10.4238/gmr16019552
Plant Genetics   Research Article

Comparison of winter and summer canola (Brassica napus) genotypes in Turkey

Authors: E. Maltas H.C. Vural

We examined genetic relationships between canola (Brassica napus) genotypes cultivated in winter and spring in Turkey. Genomic DNA was isolated from the seeds by two modified CTAB protocols: EZ1 nucleic acid isolation method and a commercial kit (Dneasy Plant Mini Kit, Qiagen). Diversity and genetic relationships in the genotypes were analyzed with RAPD m.. Read More»

Genet. Mol. Res. 12(1):
2013.February.8.5
DOI:
10.4238/2013.February.8.5
Human Genetics   Research Article

Genetic polymorphisms of the BMAP-28 and MASP-2 genes and their correlation with the somatic cell score in Chinese Holstein cattle

Authors: J. Wu, J.Y. Bai, L. Li, S. Huang, C.M. Li and G.L. Wang

DNA sequencing, nested polymerase chain reaction (PCR), and PCR-restriction fragment length polymorphism were used to investigate mutations in the coding regions of the bovine myeloid antimicrobial peptide-28 (BMAP-28) and mannan-binding lectin-associated serine protease-2 (MASP-2) genes in 249 Chinese Holstein dairy cows. The associations between the pol.. Read More»

Genet. Mol. Res. 14(1):
2015.January.15.1
DOI:
10.4238/2015.January.15.1
Human Genetics   Research Article

XRCC1 rs25487 polymorphism is associated with lung cancer risk in epidemiologically susceptible Chinese people

Authors: X. Wang, K.W. Ma, Y.G. Zhao, G.J. Wang, W. Li

Base excision repair (BER) plays an important role in maintaining genome integrity and anti-cancer drug resistance. Single nu­cleotide polymorphisms (SNPs) in BER genes were detected in 500 lung cancer patients and 500 cancer-free controls. A logistic regression model was applied to analyze the relationship between lung ca.. Read More»

Genet. Mol. Res. 14(4):
2015.December.1.3
DOI:
10.4238/2015.December.1.3
Plant Genetics   Research Article

Isolation and characterization of 8 microsatellite loci from Chrysophyllum gonocarpum (Sapotaceae)

Authors: Isolation and characterization of 8 microsatellite loci from Chrysophyllum gonocarpum (Sapotaceae)

Chrysophyllum gonocarpum is a tropical tree species that is very important in the recovery of heterogeneous forests and of degraded areas of permanent preservation. We identified microsatellite loci for C. gonocarpum to assess the genetic variability and the patterns of the population structure of the species. We isolated 8 microsatellite primers by using CT.. Read More»

Genet. Mol. Res. 12(1):
2013.February.8.6
DOI:
10.4238/2013.February.8.6
Human Genetics   Research Article

Effect of atorvastatin on plasma NT-proBNP and inflammatory cytokine expression in patients with heart failure

Authors: H.Y. Duan, D.M. Liu, P. Qian, S.L. Wang, L.J. Yan, J.T. Wu, H.T. Yang, X.W. Fan, Y.J. Chu

The aim of this study was to explore the effect of atorvastatin intervention on plasma N-terminal pro-B-type natriuretic peptide (NT-proBNP) and inflammatory cytokine levels in patients with heart failure (HF). One hundred and twenty-three HF patients were selected from our hospital and randomly divided into control (N = 61) a.. Read More»

Genet. Mol. Res. 14(4):
2015.December.1.25
DOI:
10.4238/2015.December.1.25
Human Genetics   Research Article

Correlation analysis of ultrasonic characteristics, pathological type, and molecular markers of thyroid nodules

Authors: J.J. Su, L.Z. Hui, C.J. Xi and G.Q. Su

The present study was conducted to analyze the correlation between ultrasonic characteristics, pathological type, and molecular markers of thyroid-tumor-related genes as well as to evaluate the diagnosis and prognosis of thyroid nodules. The acoustic characteristics of 130 thyroid specimens were detected. Pathological sectioning and immunohistochemical de.. Read More»

Genet. Mol. Res. 14(1):
2015.January.15.2
DOI:
10.4238/2015.January.15.2