Seventeen polymorphic microsatellite markers developed for the Javelin goby, Synechogobius hasta (Gobiidae)
Authors: C.-C. Bai, S.-F. Liu, Z.-M. Zhuang, Y.-J. Yuan, H.-B. Liu and F.-Q. Dai
Synechogobius hasta is an important commercial marine fish with distinctive features of rapid growth and short lifespan. We isolated and characterized 17 microsatellite markers for S. hasta using a (GT)13-enriched genomic library. Polymorphism was assessed in 48 individuals from a single population collected from the northern .. Read More»
- Genet. Mol. Res. 11(2):
- 2012.May.18.7
- DOI:
- 10.4238/2012.May.18.7
Mutations in NPHS1 in a Chinese child with congenital nephrotic syndrome
Authors: Z.H. Yu, D.J. Wang, D.C. Meng, J. Huang and X.J. Nie
Since the identification of the NPHS1 gene, which encodes nephrin, various investigators have demonstrated that the NPHS1 mutation is a frequent cause of congenital nephrotic syndrome (CNS); it is found in 98% of Finnish children with this syndrome and in 39-80% of non-Finnish cases. In China, compound heterozygous mutations i.. Read More»
- Genet. Mol. Res. 11(2):
- 2012.May.18.6
- DOI:
- 10.4238/2012.May.18.6
A novel mutation of the MFN2 gene in a Chinese family with Charcot-Marie-Tooth disease
Authors: Y.W. Wang, W.T. Han, M. Jiang, C.X. Lu, X.F. Li, X. Zhang and J.X. Li
Charcot-Marie-Tooth (CMT) is a group of clinically and genetically heterogeneous inherited neuromuscular disorders. At present, more than 30 loci have been reported to be associated with CMT disease; point mutations in the mitofusin 2 (MFN2) gene is one of the most common causes. We studied a Chinese family with CMT disease in.. Read More»
- Genet. Mol. Res. 11(2):
- 2012.May.18.5
- DOI:
- 10.4238/2012.May.18.5
Development of 18 microsatellite loci for the freshwater snail Bellamya aeruginosa (Mollusca, Gastropoda)
Authors: Q.H. Gu, B.X. Xiong, Y.T. Zhu, Q. Wang and P.S. Shi
Although it is a major freshwater gastropod species, genetic diversity of Bellamya aeruginosa was completely unknown. Eighteen microsatellite loci were isolated and characterized from (AC)15-enriched genomic libraries of the freshwater snail B. aeruginosa. Most of the 18 loci were successfully amplified and high polymorphic information content values were.. Read More»
- Genet. Mol. Res. 11(2):
- 2012.May.18.4
- DOI:
- 10.4238/2012.May.18.4
Meta-analysis of TP73 polymorphism and cervical cancer
Authors: H. Feng, L. Sui, M. Du and Q. Wang
The aim of this study was to investigate the tumor protein p73 (TP73) G4C14-A4T14 polymorphism and to perform a meta-analysis to assess TP73 expression in cervical cancer and precancerous tissue. Articles containing data regarding TP73 status in cervical cancer patients and healthy controls were retrieved from PubMed, EMBASE, .. Read More»
- Genet. Mol. Res. 16(1):
- gmr16016571
- DOI:
- 10.4238/gmr16016571
Relationship between lymphocyte DNA fragmentation and dose of iron oxide (Fe2O3) and silicon oxide (SiO2) nanoparticles.
Authors: J. JimÃ?©nez-Villarreal, D.I. Rivas-ArmendÃ?¡riz, R.D. Arellano PÃ?©rez-Vertti, E. Olivas CalderÃ?³n, R. GarcÃ?Âa-Garza, N.D. Betancourt-MartÃ?Ânez, L.B. Serrano-Gallardo and J. MorÃ?¡n-MartÃ?Ânez
At present, the use of nanoparticles is a controversial topic, especially when analyzing their effects in human tissues. Nanoparticles (NPs) can cause oxidative stress by increasing membrane lipids peroxidation and reactive oxygen species, and decreasing intracellular glutathione. Oxidative stress plays an important role in ce.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019206
- DOI:
- 10.4238/gmr16019206
Development and characterization of microsatellite markers for Solen grandis using Illumina sequencing approach
Authors: Y.W. Feng, H.L. Jiang, Y.T. Liu, X.P. Wu, X.Q. Liu and X.M. Wei
Solen grandis is an important economic and overexploited bivalve species. In order to perform its fine-scale genetic analyses, 105 pairs of microsatellites with polymorphism were identified through Illumina Hiseq platform and bioinformatic assembly technology in this study. The estimated fragment size ranged from 100 to 268 bp.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019621
- DOI:
- 10.4238/gmr16019621
Genetic diversity among exotic cotton accessions as for qualitative and quantitative traits
Authors: L.P. de Carvalho, F.J.C. Farias, J.I.S. Rodrigues, N.D. Suassuna and P.E. Teodoro
Studying genetic diversity among a group of genotypes is important in genetic breeding because identifying hybrid combinations of greater heterotic effect also increases the chance of obtaining plants with favorable allele combinations in an intra-population selection program. The objective of this study was to compare differe.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019590
- DOI:
- 10.4238/gmr16019590
Population genetic structure in Phyla scaberrima from Mexico and Colombia assessed by AFLP markers and implications for conservation
Authors: L.G. Androcioli, E.A. Ruas, L.A. Rodrigues, C.F. Ruas , H.E.R. Perilla, P.M. Ruas
Phyla scaberrima (Verbenaceae) is a herbaceous perennial species that is distributed from Mexico (center of origin) to Colombia, growing in forest and swamp edges or grasslands from sea level up to an altitude of 1800 m. The chemical properties and uses in popular medicine have drastically affected the population siz.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.1.21
- DOI:
- 10.4238/2015.December.1.21
SYBR safeTM efficiently replaces ethidium bromide in Aspergillus fumigatus gene disruption
Authors: H.M.S. Canela, L.A. Takami and M.E.S. Ferreira
Invasive aspergillosis is a disease responsible for high mortality rates, caused mainly by Aspergillus fumigatus. The available drugs are limited and this disease continues to occur at an unacceptable frequency. Gene disruption is essential in the search for new drug targets. An efficient protocol for A. fumigatus gene disrupt.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019583
- DOI:
- 10.4238/gmr16019583