Electroacupuncture decreases the urinary bladder pressure in patients with acute gastrointestinal injury
Authors: H.J. Yu, J.G. Zhu, P. Shen, L.H. Shi, Y.C. Shi and F. Chen
Aseptic loosening associated with wear particle-induced inflammation is a major cause of joint implant failure. Recent studies have demonstrated the therapeutic effects of p38 mitogen-activated protein kinase (MAPK)-based therapies on chronic inflammatory diseases. The purpose of this study was to investigate whether SB203580, a p38 MAPK inhibitor, inhibi.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.January.15.5
- DOI:
- 10.4238/2015.January.15.5
Evolutionary analysis of the short-type peptidoglycan-recognition protein gene (PGLYRP1) in primates
Authors: W. Liu Y.F. Yao L. Zhou Q.Y. Ni H.L. Xu
Short-type peptidoglycan (PGN)-recognition protein 1 (PGLYRP1), an innate immunity protein that directly breaks down the structure of microbial cell wall PGNs, plays an important role both in antibacterial defenses and several inflammatory diseases. To explore the adaptive evolution of the PGLYRP1 gene in primates and provide insight into the function of thi.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.February.8.10
- DOI:
- 10.4238/2013.February.8.10
Physiological evaluation of the responses of Larix olgensis families to drought stress and proteomic analysis of the superior family
Authors: L. Zhang, H.G. Zhang, Q.Y. Pang
The conifer Larix olgensis has been analyzed to delineate physiological and proteomic changes that occur under drought stress. Studies of the deleterious effects of drought in the larch families have mainly focused on photosynthesis. In the present study, when the intensity of drought was increased, plant height was inhibited .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.1.9
- DOI:
- 10.4238/2015.December.1.9
Protective effect of p38 MAPK inhibitor on wear debris-induced inflammatory osteolysis through downregulating RANK/RANKL in a mouse model
Authors: D. Chen, Y. Li, F. Guo, Z. Lu, C. Hei, P. Li and Q. Jin
Adult stem cells are known for their plasticity and their potential to differentiate into several different cell types; these characteristics have implications for cell therapy and reproductive biotechnologies. In this study, we report on the isolation and characterization of mesenchymal stem cells (MSC) derived from bovine and buffalo adipose tissue. Cel.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.January.15.6
- DOI:
- 10.4238/2015.January.15.6
Generation of bovine (Bos indicus) and buffalo (Bubalus bubalis) adipose tissue derived stem cells: isolation, characterization, and multipotentiality
Authors: R.V. Sampaio, M.R. Chiaratti, D.C.N. Santos, F.F. Bressan, J.R. Sangalli, A.L.A. S�¡, T.V.G. Silva, N.N. Costa, M.S. Cordeiro, S.S.D. Santos, C.E. Ambrosio, P.R. Adona, F.V. Meirelles, M.S. Miranda and O.M. Ohashi
Previous studies have indicated that the protein tyrosine phosphatase nonreceptor type 22 gene (PTPN22) is associated with type 1 diabetes (T1DM) in the Caucasian population. In the present study, we investigated the relationship between PTPN22 genetic polymorphisms and T1DM in Chinese children. A total of 202 children and adolescents with T1DM and 240 he.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.January.15.7
- DOI:
- 10.4238/2015.January.15.7
Chromosomal diversity in Hypostomus (Siluriformes, Loricariidae) with emphasis on physical mapping of 18S and 5S rDNA sites
Authors: J.B. Traldi D.R. Blanco M.R. Vicari J.F. Martinez R.L. Lui A.V. Barros R.F. Artoni O. Moreira-Filho
We examined chromosomes of three species of the genus Hypostomus, in order to contribute to the understanding of the karyotype evolution of this group. Specimens of H. ancistroides and H. nigromaculatus displayed differences in karyotype formulas, distribution and location of heterochromatin and nucleolus organizer regions when compared to other populations .. Read More»
- Genet. Mol. Res. 12(1):
- 2013.February.8.11
- DOI:
- 10.4238/2013.February.8.11
Identification and association of polymorphisms in CAPN1 and CAPN3 candidate genes related to performance and meat quality traits in chickens
Authors: A.M. FelÃ?Âcio C. Boschiero J.C.C. Balieiro M.C. Ledur J.B.S. Ferraz T. Michelan Filho A.S.A.M.T. Moura L.L. Coutinho
Meat quality is an important feature for the poultry industry and is associated with consumer satisfaction. The calpain 1 (CAPN1) gene is related to the tenderness process of meat post- mortem, and the calpain 3 (CAPN3) gene plays an important role in myofibrillar organization and growth. The objective of the present study was to identify polymorphisms in.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.February.8.12
- DOI:
- 10.4238/2013.February.8.12
Analysis of the cytochrome c oxidase subunit II (COX2) gene in giant panda, Ailuropoda melanoleuca
Authors: S.S. Ling, Y. Zhu, D. Lan, D.S. Li, H.Z. Pang, Y. Wang, D.Y. Li, R.P. Wei, H.M. Zhang, C.D. Wang and Y.D. Hu
The giant panda, Ailuropoda melanoleuca (Ursidae), has a unique bamboo-based diet; however, this low-energy intake has been sufficient to maintain the metabolic processes of this species since the fourth ice age. As mitochondria are the main sites for energy metabolism in animals, the protein-coding genes involved in mitochond.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019158
- DOI:
- 10.4238/gmr16019158
Identification of resistance gene analogs in Korean wild apple germplasm collections
Authors: D.E. Baek C. Choi
Several plant disease resistance gene (R-gene) classes have been identified on the basis of specific conserved functional domains. Cloning of disease-resistance apple genes would be useful for breeding programs and for studying resistance mechanisms. We used a PCR approach with degenerate primers designed from conserved NBS-LRR (nucleotide binding site-le.. Read More»
- Genet. Mol. Res. 13(1):
- 2013.January.30.2
- DOI:
- 10.4238/2013.January.30.2
Dynamics of 45S rDNA sites in the cell cycle: fragile sites and chromosomal stability in Lolium and Festuca
Authors: L.C. Rocha, G.A. Silva, F.O. Bustamante, R.A.D. Silveira,A. Mittlemann and V.H. Techio
Analyses carried out with fluorescence in situ hybridization (FISH) in C-metaphases of the Lolium-Festuca complex have shown the occurrence of spontaneous fragile sites (FSs) in 45S rDNA regions. FSs are expressed as gaps but they do not result in breaks or chromosomal fragments in these species. These gaps have high DNA conde.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019156
- DOI:
- 10.4238/gmr16019156