Next-generation sequencing analysis of the ARMS2 gene in Turkish exudative age-related macular degeneration patients
Authors: H. Bardak, M. Gunay, Y. Ercalik, Y. Bardak, H. Ozbas and O. Bagci
Age-related macular degeneration (AMD) is the leading cause of blindness in developed countries. It is a complex disease with both genetic and environmental risk factors. To improve clinical management of this condition, it is important to develop risk assessment and prevention strategies for environmental influences, and esta.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019135
- DOI:
- 10.4238/gmr16019135
An experimental study on the use of icariin for improving thickness of thin endometrium
Authors: A.W. Le, Z.H. Wang, X.Y. Dai, T.H. Xiao, R. Zhuo, B.Z. Zhang, Z.L. Xiao and X.J. Fang
This study aimed to investigate the effect of icariin (ICA) on thin endometrium in a rat model. To this end, 6- to 8-week-old female Sprague Dawley rats (105) were randomly divided into 7 groups: untreated, vehicle-treated (lavage with NaCl), high-dose ICA (lavage with ICA at 200 mgâÂ?Â?kg-1âÂ?Â?day-1), medium-dose ICA (lava.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019126
- DOI:
- 10.4238/gmr16019126
Effects of feeding conditions on gene expression in chicken breast muscle
Authors: G.L. Gao, C. Wang, X.Z. Zhao, H.W. Wang, Q. Li, J. Li, K.S. Zhang, H. Zhong and Q.G. Wang
Chicken meat quality is becoming increasingly important among breeders and consumers. To understand the effect of feeding conditions on chicken meat quality, we investigated the profiles of genes expressed in chicken breast muscle. Using RNA sequencing, we identified 336, 321, and 387 differentially expressed genes among Cheng.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019119
- DOI:
- 10.4238/gmr16019119
Genetic diversity of Casearia sylvestris populations in remnants of the Atlantic Forest
Authors: F.L. Araujo, M.V.B.M. Siqueira, C. Grando, J.P.G. Viana, J.B. Pinheiro, A. Alves-Pereira, J.B. Campos, P.H.S. Brancalion and M.I. Zucchi
Guaçatonga (Casearia sylvestris) is a native plant of the Atlantic Forest, with high medicinal potential and relevance for reforestation programs. The aim of this study was to characterize, with microsatellite markers, two populations of C. sylvestris from remaining areas of the Atlantic Forest in the State of Sã.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019105
- DOI:
- 10.4238/gmr16019105
An assessment of the correlation between early postinfarction pyramidal tract Wallerian degeneration and nerve function recovery using diffusion tensor imaging
Authors: A.H. Guo, F.L. Hao, L.F. Liu, B.J. Wang and X.F. Jiang
This study aimed to evaluate the clinical significance of diffusion tensor imaging (DTI) in the early diagnosis of pyramidal tract Wallerian degeneration (WD) and assessment of neurological recovery following cerebral infarction. This study included 23 patients with acute cerebral infarction and 10 healthy adult controls. All .. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019035
- DOI:
- 10.4238/gmr16019035
Expression of prion protein in the cerebrospinal fluid of patients with Parkinson�s disease complicated with rapid eye movement sleep behavior disorder
Authors: W.J. Zhang, X.L. Shang, J. Peng, M.H. Zhou and W.J. Sun
Parkinson’s disease (PD) is one of the most common neurodegenerative diseases and mainly manifests with decreasing numbers of dopaminergic neurons. Rapid eye movement (REM) sleep behavior disorder (RBD) has an incidence of 15-47% in all PD patients. Prion proteins (PrPs), which are expressed in both neurons and glial cel.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019022
- DOI:
- 10.4238/gmr16019022
Potential use of molecular markers for prediction of genotypic values in hybrid maize performance
Authors: M. Balestre, R.G. Von Pinho, J.C. Souza and R.L. Oliveira
We evaluated the potential of genetic distances estimated by microsatellite markers for the prediction of the performance of single-cross maize hybrids. We also examined the potential of molecular markers for the prediction of genotypic values and the applicability of the Monte Carlo method for a correlation of genetic distanc.. Read More»
- Genet. Mol. Res. 8(4):
- vol8-4gmr644
- DOI:
- 10.4238/vol8-4gmr644
Genetic diversity of Cajazeira (Spondias mombin L.) in three geographic regions
Authors: B.M. Silva, A.A.B. Rossi, A.V. Tiago, K.F.M. Schmitt, J.F.E. Dardengo and S.A.M. Souza
Cajazeira (Spondias mombin L.), of the family Anacardiaceae, is a species of fruit tree found in the Amazon region with fruits that have excellent prospects for commercial use. We aimed to evaluate the genetic diversity within and among natural populations of S. mombin, with natural occurrence in northern Mato Grosso State, by.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16018946
- DOI:
- 10.4238/gmr16018946
Phenotypic and molecular characterization of a tomato (Solanum lycopersicum L.) F2 population segregation for improving shelf life
Authors: K.N. Yogendra P.H. Ramanjini Gowda
Breeding for better quality fruits is a major focus for tomatoes, which are continuously subjected to post-harvest losses. Several methods have been used to improve the fruit shelf life of tomatoes, including the use of ripening gene mutants of Solanum lycopersicum. We developed extended shelf-life tomato hybrids with better quality fruits using ripening .. Read More»
- Genet. Mol. Res. 12(1):
- 2013.January.9.4
- DOI:
- 10.4238/2013.January.9.4
Identification of polymorphisms and transcriptional activity of the proto-oncogene KIT located on both autosomal and B chromosomes of the Chinese raccoon dog
Authors: Y.M. Li1, Y. Zhang1, W.J. Zhu1, S.Q. Yan1 and J.H. Sun2
B chromosomes are dispensable and co-exist with autosomal and sex chromosomes. The karyotype of the Chinese raccoon dog (Nyctereutes procyonoides procyonoides) comprises 0-4 B chromosomes. The proto-oncogene KIT is found on all B chromosomes of the Chinese raccoon dog. In the present study, partial DNA and mRNA sequences of KIT were amplified and sequence.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017398
- DOI:
- 10.4238/gmr.15017398