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Plant Genetics   Research Article

Genetic relationships in a germplasm collection of Camellia japonica and Camellia oleifera using SSR analysis

Authors: Y. Zhao, C.J. Ruan, G.J. Ding and S. Mopper

Camellia japonica produces different color and bigger flowers, widely being used for gardening green in southern China. However, cultivars were introduced from different regions, but their origin and pedigree information is either not available poorly documented, causing problems in authentication. Many low-yield trees in Came.. Read More»

Genet. Mol. Res. 16(1):
gmr16019526
DOI:
10.4238/gmr16019526
Plant Genetics   Research Article

Comparative evaluation of total RNA extraction methods in Theobroma cacao using shoot apical meristems

Authors: D.V. Silva1, S.M.J. Branco1, I.S.A. Holanda2, S. Royaert3, J.C. Motamayor4,J.P. Marelli4 and R.X. Corr�ªa5

Theobroma cacao is a species of great economic importance with its beans used for chocolate production. The tree has been a target of various molecular studies. It contains many polyphenols, which complicate the extraction of nucleic acids with the extraction protocols requiring a large amount of plant material. These issues, therefore, necessitate the op.. Read More»

Genet. Mol. Res. 15(1):
gmr.15017364
DOI:
10.4238/gmr.15017364
Human Genetics   Research Article

Vasculogenic mimicry and hypoxia-inducible factor-1�± expression in cervical squamous cell carcinoma

Authors: T.J. Zhou1, X.H. Huang1, L. Gong1 and L. Xiang2

In this study, the existence of vasculogenic mimicry (VM) in cervical squamous cell carcinoma was investigated. To this end, the relationship between hypoxia-inducible factor 1α (HIF-1α) and the development, infiltration, and metastasis of cervical squamous cell carcinoma was studied. Between January 2010 and December 2010, 67 human cervical s.. Read More»

Genet. Mol. Res. 15(1):
gmr.15017396
DOI:
10.4238/gmr.15017396
Human Genetics   Research Article

CsSAD: a fatty acid desaturase gene involved in abiotic resistance in Camellia sinensis (L.)

Authors: Z.T. Ding1,2*, J.Z. Shen1,2*, L.L. Pan1,2, Y.U. Wang1,2, Y.S. Li3, Y. Wang4 andH.W. Sun5

Tea (Camellia sinensis L.) is a thermophilic evergreen woody plant that has poor cold tolerance. The SAD gene plays a key role in regulating fatty acid synthesis and membrane lipid fluidity in response to temperature change. In this study, full-length SAD cDNA was cloned from tea leaves using rapid amplification of cDNA ends and polymerase chain reaction .. Read More»

Genet. Mol. Res. 15(1):
gmr.15017512
DOI:
10.4238/gmr.15017512
Plant Genetics   Research Article

Assessment of genetic diversity of cotton genotypes for various economic traits against cotton leaf curl disease (CLCuD)

Authors: M. Javed, S.B. Hussain and M. Baber

In Pakistan, cotton crop has been under enormous threat of cotton leaf curl disease (CLCuD) over the last four decades. In order to estimate genetic diversity in cotton germplasm CLCuD resistance, we assessed 100 cotton genotypes for their CLCuD resistance/tolerance and other related agronomical traits. Various statistical ana.. Read More»

Genet. Mol. Res. 16(1):
gmr16019446
DOI:
10.4238/gmr16019446
Animal Genetics   Research Article

Expression of MMP-1, -2, and -8 in longissimus dorsi muscle and their relationship with meat quality traits in cattle

Authors: Y.X. Qi, X.H. Zhang, Y.Q. Wang, Y.Z. Pang, Z.B. Zhang, T.L. Zhang andZ.X. Zhang

The extracellular matrix (ECM) is the major macromolecule in skeletal muscle, which affects meat quality greatly. The remodeling of the ECM is mainly regulated by matrix metalloproteinases (MMPs). The expression patterns of MMP-1, -2, and -8 in longissimus dorsi muscle were explored using quantitative real-time polymerase chain reaction. The results show .. Read More»

Genet. Mol. Res. 14(1):
gmr.15017593
DOI:
10.4238/gmr.15017593
Human Genetics   Research Article

Inhibition of mitochondrial calcium uptake 1 in Drosophila neurons

Authors: P.G. M�Angale and B.E. Staveley

The mitochondrial calcium uptake 1 (MICU1) is a regulatory subunit of the mitochondrial calcium uniporter that plays an important role in calcium sensing. It contains two EF-hand domains that are well conserved across diverse species from protozoa to plants and metazoans. The loss of MICU1 function in mammals is attributed to .. Read More»

Genet. Mol. Res. 16(1):
gmr16019436
DOI:
10.4238/gmr16019436
Animal Genetics   Research Article

Differential expression of FUT1 and FUT2 in Large White, Meishan, and Sutai porcine breeds

Authors: R.W. Xia1, W.Y. Qin1, L.N. Gan1, J. Wang1, S.L. Wu1,2 and W.B. Bao1,2

To assess the relationship between the expression of a(1,2)-fucosyltransferase (FUT1 and FUT2) genes and resistance to Escherichia coli F18 in weaned pigs, FUT1 and FUT2 expression levels in Large White, Meishan, and Sutai pigs (with resistance to E. coli F18) were determined using real-time PCR. The results revealed that FUT1 and FUT2 expression levels w.. Read More»

Genet. Mol. Res. 15(1):
gmr.15017613
DOI:
10.4238/gmr.15017613
Human Genetics   Research Article

Migration and invasion enhancer 1 (MIEN1) is overexpressed in breast cancer and is a potential new therapeutic molecular target

Authors: H.-B. Zhao, X.-F. Zhang, H.-B. Wang and M.-Z. Zhang

Migration and invasion enhancer 1 (MIEN1) is a membrane-anchored protein that is highly expressed in various types of cancer, and is correlated with the PI3K/AKT pathway. The aim of this study was to investigate the expression of MIEN1 and its clinical pathological significance in breast cancer. We used immunohistochemical sta.. Read More»

Genet. Mol. Res. 16(1):
gmr16019380
DOI:
10.4238/gmr16019380
Human Genetics   Research Article

Common genetic risk factors of venous thromboembolism in Western and Asian populations

Authors: S.S. Huang1*, Y. Liu2*, Z.C. Jing3, X.J. Wang3 and Y.M. Mao1

Venous thromboembolism (VTE) is a multifactorial disorder involving both acquired and genetic risk factors. The common genetic factors in Western populations have been studied and reported for several decades, while studies on Asian populations are relatively scarce. Evidence suggests that the prevalence and genetic risk factors of VTE vary significantly .. Read More»

Genet. Mol. Res. 15(1):
gmr.15017644
DOI:
10.4238/gmr.15017644