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Plant Genetics   Research Article

Complete mitochondrial genome of the Amur hedgehog Erinaceus amurensis (Erinaceidae) and higher phylogeny of the family Erinaceidae

Authors: N.H. Kim, S.J. Lim, H.M. Chae and Y.C. Park

We sequenced and characterized the complete mitogenome (KX964606) of the Amur hedgehog Erinaceus amurensis to provide more data for comparative mitogenomics of the genus Erinaceus (Erinaceidae). The mitogenome of E. amurensis is a circular molecule 16,941 bp long, consisting of a control region and a conserved set of 37 genes .. Read More»

Genet. Mol. Res. 16(1):
gmr16019300
DOI:
10.4238/gmr16019300
Plant Genetics   Research Article

Extraction of proteins and preliminary characterization of physicochemical properties in Toona sinensis fruit

Authors: W.-Z. Li, W.-N. Han, B. Liu, S.-H. Ding, X.-K. Zhang and R.-S. Wang

We investigated the extraction of Toona sinensis fruit proteins and preliminarily characterized their physicochemical properties. The results showed that optimal extraction occurred under conditions of pH 10.5, a duration of 40 min, a liquid-to-solid ratio of 25:1, and a temperature of 40°C by an orthogonal design using T... Read More»

Genet. Mol. Res. 16(1):
gmr16019177
DOI:
10.4238/gmr16019177
Human Genetics   Research Article

Correlation of aberrant expression of p53, Rad50, and cyclin-E proteins with microsatellite instability in gallbladder adenocarcinomas

Authors: P.K. Mishra, S.K. Jatawa, G.V. Raghuram, N. Pathak, A. Jain,A. Tiwari, S. Varshney and K.K. Maudar

Gallbladder carcinoma is an uncommon, but highly malignant tumor, with poor prognostic, and diagnostic manifestations in early stages. The Indian Council of Medical Research reported increased incidence of gallbladder carcinoma in the surviving population of the Bhopal gas tragedy that involved exposure of more than 500,000 pe.. Read More»

Genet. Mol. Res. 8(4):
vol8-4gmr653
DOI:
10.4238/vol8-4gmr653
Human Genetics   Research Article

Effects of grafting on key photosynthetic enzymes and gene expression in the citrus cultivar Huangguogan

Authors: L. Liao1, S.Y. Cao1, Y. Rong1 and Z.H. Wang1,2

Grafting influences scion photosynthetic capacity and fruit quality. Ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco), which strongly affects photosynthetic rate, and Rubisco activase (RCA), which regulates Rubisco activity, are two key photosynthetic enzymes. However, little information is available regarding the effect of grafting on the concen.. Read More»

Genet. Mol. Res. 15(1):
gmr.15017690
DOI:
10.4238/gmr.15017690
Human Genetics   Research Article

Effect of GJB2 235delC and 30-35delG genetic polymorphisms on risk of congenital deafness in a Chinese population

Authors: Y. Xiong, M. Zhong, J. Chen, Y.L. Yan, X.F. Lin and X. Li

Congenital deafness is a serious and irreversible condition in humans. The GJB2 gene is implicated in the pathogenesis of autosomal recessive nonsyndromic hearing loss. Its 235delC and 30-35delG polymorphisms are reported to be associated with risk of hereditary deafness. However, the effect of the interaction between GJB2 235.. Read More»

Genet. Mol. Res. 16(1):
gmr16019165
DOI:
10.4238/gmr16019165
Animal Genetics   Research Article

Molecular characterization, expression, and functional analysis of chicken TRAF6

Authors: J. Jin, J.S. Ran, C.W. Yang, X.S. Jiang, Y.G. Zhou, Z.Q. Feng, Y. Wang, D. Lan, P. Ren and Y.P. Liu

Tumor necrosis factor receptor-associated factor 6 (TRAF6) is a crucial adaptor molecule of the interleukin-1 receptor/Toll-like receptor (IL-1/TLR) superfamily, which can trigger downstream signaling cascades involved in innate immunity. The function of TRAF6 has been clarified in mammals but is poorly understood in chicken. .. Read More»

Genet. Mol. Res. 16(1):
gmr16019138
DOI:
10.4238/gmr16019138
Human Genetics   Research Article

Expression of microRNA-210 in tissue and serum of renal carcinoma patients and its effect on renal carcinoma cell proliferation, apoptosis, and invasion

Authors: T.Y. Liu1, H. Zhang2, S.M. Du3, J. Li1 and X.H. Wen1

This study investigated the expression of microRNA-210 (miR-210) in tissue and serum of renal carcinoma patients and its effect on renal carcinoma cell proliferation, apoptosis, and invasion. Thirty-two renal carcinoma patients in our hospital were selected as the study group and 32 people receiving a physical examination were selected as the control grou.. Read More»

Genet. Mol. Res. 15(1):
gmr.15017746
DOI:
10.4238/gmr.15017746
Human Genetics   Research Article

First cytogenetic study of Cavernicola pilosa Barber, 1937 (Hemiptera, Triatominae)

Authors: E.S. Souza, K.C.C. Alevi, A.R. Ribeiro, M.B. Furtado, N.C.B.V. Atzingen, M.T.V. Azeredo-Oliveira and J.A. Rosa

Cavernicola pilosa is a triatomine species that lives in caves and feeds on bat blood. This vector has a wide geographical distribution, and is found in Brazil, Colombia, Panama, Peru, and Venezuela. Little is known about the reproductive biology of this species, because most previous studies have only characterized its morphology, morphometry, ecology, a.. Read More»

Genet. Mol. Res. 14(4):
2015.October.29.9
DOI:
10.4238/2015.October.29.9
Microbial Genetics   Research Article

Cloning and expression of class I chitinases in Hami melon after Penicillium infection

Authors: F.Y. Jiang, B.B. Shui, F.X. Tang and C.H. Shan

Chitinases are important disease-related proteins that play critical roles in plant defense against disease. To investigate the function of chitinases in the resistance of Hami melon to Penicillium infection, the gene encoding chitinases, HmCHT-2, was cloned and RT-PCR was used to measure expression levels of HmCHT-2. When the.. Read More»

Genet. Mol. Res. 16(1):
gmr16019085
DOI:
10.4238/gmr16019085
Medical Genetics   Research Article

Vascular endothelial growth factor -634 G/C polymorphism and risk of cancer: an updated meta-analysis

Authors: J.Y. Ban, J.I. Shin and C.-H. Oh

The association between vascular endothelial growth factor (VEGF) gene polymorphisms and risk of cancer has been investigated in several studies published previously; however, the individual results are inconclusive. Therefore, we performed a meta-analysis to establish evidence for an association between the VEGF -634 G/C polymorphism and risk of cancer. .. Read More»

Genet. Mol. Res. 14(4):
2015.October.29.11
DOI:
10.4238/2015.October.29.11