Early selection of sugarcane using path analysis
Authors: R.P. Barbosa, F. Alc�¢ntara Neto, L.M. Gravina, G.A. Gravina, M.G.T. Portela and A.A.C. Bezerra
The aim of this study was to analyze sugarcane (Saccharum officinarum) biometric and technological data, obtained at different timepoints, using path analysis. The experiment was conducted in União, PI, Brazil, and evaluated 12 sugarcane genotypes (RB036066, RB9438, RB935744, RB021764, RB021754, RB021534, RB966229, RB97.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019038
- DOI:
- 10.4238/gmr16019038
Molecular identification of Echinococcus granulosus on the Tibetan Plateau using mitochondrial DNA markers
Authors: D. Hu, X. Song, N. Wang, X. Zhong, J. Wang, T. Liu, Z. Jiang, T. Dawa, X. Gu, X. Peng and G. Yang
Cystic echinococcosis (CE) is an important worldwide zoonotic disease that causes large economic losses and human suffering. Echinococcus granulosus, the causative agent of CE, exhibits different genotypes in different locations. In order to identify its genotypes and analyze its genetic structure on the Tibetan Plateau, we collected 72 hydatid cysts from.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.29.12
- DOI:
- 10.4238/2015.October.29.12
Nested polymerase chain reaction technique for the detection of Gpc3 and Afp mRNA in liver cancer micrometastases
Authors: J. Luo, K. Yang and Y.G. Wen
The incidence of liver cancer has gradually risen to a high level in China, and tumor metastasis occurs via multiple pathways. Alpha fetal protein (AFP) is the main biomarker of liver cancer micrometastases. A recent study showed that glypican-3 (GPC3), which is abundant in hepatoma cells, has promising specificity and could b.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16018947
- DOI:
- 10.4238/gmr16018947
Characterization of the inaA gene and expression of ice nucleation phenotype in Pantoea ananatis isolates from Maize White Spot disease
Authors: A.M. Miller1, J.E.F. Figueiredo3, G.A. Linde4, N.B. Colauto4and L.D. Paccola-Meirelles1,2,4
Maize White Spot (MWS), a foliar disease caused by Pantoea ananatis, could cause up to 60% yield loss. Some strains of P. ananatis harboring the ice nucleation gene inaA catalyze the formation of ice nuclei, causing tissue damage at temperatures slightly below freezing. Little is known about the relationship between the presence of the ina gene in this ma.. Read More»
- Genet. Mol. Res. 15(1):
- 0.4238/gmr.15017863
- DOI:
- 0.4238/gmr.15017863
ESR1 gene polymorphisms PvuII (rs2234693T>C) and XbaI (rs9340799A>G) may not be directly correlated with cardiovascular disease risk
Authors: N. Jiang, G. Yang and C.L. Peng
The aim of this meta-analysis was to evaluate the correlations between the estrogen receptor 1 (ESR1) gene polymorphisms PvuII (rs2234693T>C) and XbaI (rs9340799A>G) and the risk of cardiovascular disease (CVD). Case-control studies were screened and selected from a larger group of studies that were retrieved through a comprehensive search of scient.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.29.14
- DOI:
- 10.4238/2015.October.29.14
Paclitaxel induces apoptosis in leukemia cells through a JNK activation-dependent pathway
Authors: Z.G. Peng1, D.C. Liu2, Y.B. Yao1, X.L. Feng3, X. Huang1, Y.L. Tang1, J. Yang1 and X.X. Wang1
Paclitaxel (PTX) is a mitotic inhibitor widely used in chemotherapy for many types of cancers, including solid tumors and hematological malignancies. However, the molecular basis of the anti-proliferation activity of PTX is not fully understood. In this paper, we focused on the role of c-Jun N-terminal kinase (JNK) pathways in PTX-induced apoptosis and pr.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15013904
- DOI:
- 10.4238/gmr.15013904
Lack of association of C282Y and H63D mutations in the hemochromatosis (HFE) gene with diabetes mellitus type 2 in a case-control study of women in Brazil
Authors: K.B. Gomes, M.G. Carvalho, F.F. Coelho, I.F. Rodrigues, A.L. Soares, D.A. Guimar�£es and A.P. Fernandes
Hereditary hemochromatosis is one of the most common autosomal recessive diseases; it is characterized by excess absorption of iron. Clinically, the major challenge is to diagnose increased iron deposition before irreversible tissue damage has occurred. C282Y and H63D are the main mutations related to hereditary hemochromatosi.. Read More»
- Genet. Mol. Res. 8(4):
- vol8-4gmr663
- DOI:
- 10.4238/vol8-4gmr663
Phenotypic and RAPD diversity among 80 germplasm accessions of the medicinal plant isabgol (Plantago ovata, Plantaginaceae)
Authors: N. Singh, R.K. Lal and A.K. Shasany
Plantago ovata, popularly known as isabgol, has great commercial and medicinal importance due to thin rosy white membranous seed husk. Isabgol seeds and husks have emollient, demulcent and laxative properties. We used both biometric and molecular techniques to assess the genetic variability and relatedness of 80 germplasm acce.. Read More»
- Genet. Mol. Res. 8(4):
- vol8-4gmr583
- DOI:
- 10.4238/vol8-4gmr583
SSR analysis demonstrates that olive production in the southern Marmara region in Turkey uses a single genotype
Authors: A. Ipek, E. Barut, H. Gulen, A.T. Oz, N.A. Tangu and M. Ipek
The southern Marmara region in Turkey was surveyed to determine the olive cultivars that are used for olive production. Genetic diversity analysis using simple sequence repeat (SSR) markers indicated that the cultivar Gemlik is the major olive cultivar grown in this region, while other olive cultivars are grown only for use as.. Read More»
- Genet. Mol. Res. 8(4):
- vol8-4gmr659
- DOI:
- 10.4238/vol8-4gmr659
Concurrent sequence variation of TP53 and TP73 genes in anaplastic astrocytoma
Authors: N.P. Anselmo, J.A. Rey, L.O. Almeida, A.C. Cust�³dio,J.R.W. Almeida, C.A. Clara, M.J. Santos and C. Casartelli
Disruption or loss of tumor suppressor gene TP53 is implicated in the development or progression of almost all different types of human malignancies. Other members of the p53 family have been identified. One member, p73, not only shares a high degree of similarity with p53 in its primary sequence, but also has similar function.. Read More»
- Genet. Mol. Res. 8(4):
- vol8-4gmr631
- DOI:
- 10.4238/vol8-4gmr631