Desmoglein 4 diversity and correlation analysis with coat color in goat
Authors: G.X. E1, Y.J. Zhao1, Y.H. Ma2, G.L. Cao3, J.N. He4, R.S. Na1, Z.Q. Zhao1,C.D. Jiang1, J.H. Zhang1, S. Arlvd5, L.P. Chen1, X.Y. Qiu1, W. Hu1 and Y.F. Huang1
Desmoglein 4 (DSG4) has an important role in the development of wool traits in domestic animals. The full-length DSG4 gene, which contains 3918 bp, a complete open-reading-frame, and encodes a 1040-amino acid protein, was amplified from Liaoning cashmere goat. The sequence was compared with that of DSG4 from other animals and the results show that the DSG.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017814
- DOI:
- 10.4238/gmr.15017814
Meta-analysis demonstrates association between TLR polymorphisms and rheumatoid arthritis
Authors: Y.H. Lee S.-C. Bae G.G. Song
We investigated whether Toll-like receptor (TLR) polymorphisms confer susceptibility to rheumatoid arthritis and whether they influence clinical characteristics of rheumatoid arthritis. Studies were considered relevant for our meta-analysis if at least two comparisons of an issue were available. Eleven studies with 2078 patients with rheumatoid arthritis .. Read More»
- Genet. Mol. Res. 12(1):
- 2013.February.7.2
- DOI:
- 10.4238/2013.February.7.2
Isolation and characterization of novel polymorphic microsatellite markers for Epinephelus akaara
Authors: Z.Z. Xie, L.Y. Zheng, L. Tang, Z.J. Tang, S.S. Li, Y. Zhang and H.R. Lin
In the present study, ten novel microsatellite markers were developed from an enriched-(CA)13 genomic library of Epinephelus akaara. The mean number of alleles per locus was 21.6, with a range of 12 to 33. Observed heterozygosity ranged from 0.767 to 0.967, and expected heterozygosity ranged from 0.831 to 0.975, with mean values of 0.877 and 0.923, respec.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.28.28
- DOI:
- 10.4238/2015.October.28.28
SRAP analysis of DNA base sequence changes in lotus mutants induced by Fe+ implantation
Authors: C.L. Deng R.Y. Qin J. Gao Y.Y. Jia Y.X. Ren W.J. Gao L.D. Lu
Ion implantation, a new biophysically mutagenic technique, has shown great potential for crop breeding. To reveal the mutation effect of low-energy ion implantation on Baiyangdian red lotus, sequence-related amplified polymorphism markers were used to amplify and detect the DNA sequence differences in mutants induced by Fe+ ion implantation. A total of 12.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.February.7.3
- DOI:
- 10.4238/2013.February.7.3
Effects of probucol on cultured human umbilical vein endothelial cells injured by hypoxia/reoxygenation
Authors: Y.L. Chai, J.Z. Xu, Y.L. Zhang and G.T. Sheng
There is increasing evidence suggesting that endoplasmic reticulum stress (ERS) plays an important role in the initiation and development of atherosclerosis. This study was designed to examine the effect of probucol on cultured human umbilical vein endothelial cells (HUVECs) injured by hypoxia/reoxygenation (H/R) and the potential mechanisms involving ERS.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15016752
- DOI:
- 10.4238/gmr.15016752
Characterization of eight novel microsatellite markers in the green-lipped mussel Perna viridis (Mytilidae)
Authors: Y.Y. Cao Z.B. Li Q.H. Li X.J. Chen L. Chen G. Dai
The green lipped mussel, also known as the Asian green mussel (Perna viridis) is a fast reproducing and valuable food source, but it is also considered an invasive species and can clog and damage pipes and marine equipment. Eight novel polymorphic microsatellite loci for P. viridis were isolated and characterized. Microsatellite polymorphism was evaluated.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.February.7.4
- DOI:
- 10.4238/2013.February.7.4
Structure and dynamics of the monomer of protein E of dengue virus type 2 with unprotonated histidine residues
Authors: L. Degr�¨ve C.A. Fuzo
The surface of the dengue virus is composed of 180 copies of a multifunctional envelope glycoprotein that acts at several stages of viral infection. When the virus is in the endosome, these glycoproteins undergo major conformational rearrangements owing to the protonation of histidine side chains. This protonation allows for the formation of trimers, thereby.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.February.7.5
- DOI:
- 10.4238/2013.February.7.5
VEGF, eNOS, and ABCB1 genetic polymorphisms may increase the risk of osteonecrosis of the femoral head
Authors: Z.C. Zhou, S.Z. Gu, J. Wu and Q.W. Liang
We investigated the associations between vascular endothelial growth factors (VEGF), endothelial nitric oxide synthase (eNOS), and ATP-binding cassette subfamily B member 1 transporter (ABCB1) polymorphisms and the risk of osteonecrosis of the femoral head (ONFH). Published studies were reviewed and analyzed based on predefined selection criteria. The str.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.28.31
- DOI:
- 10.4238/2015.October.28.31
Characterization of a rice germin-like protein gene promoter
Authors: T. Mahmood T. Yasmin M.I. Haque S.M.S. Naqvi
Germin and germin-like proteins (GLPs) are water-soluble extracellular proteins that are expressed in response to specific environmental and developmental signals. Although some enzymatic activities have also been associated with germin/GLPs, their role in overall metabolism is not fully understood. However, insight into their function may be gained by an.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.February.7.6
- DOI:
- 10.4238/2013.February.7.6
Microsatellite markers for genetic studies of the fall armyworm, Spodoptera frugiperda
Authors: V.A.C. Pavinato S. Martinelli P.F. de Lima M.I. Zucchi C. Omoto
We developed six microsatellite markers for the fall armyworm Spodoptera frugiperda (Lepidoptera: Noctuidae). The SSR loci were isolated with enriched genomic library protocol by using native individuals as a genome source for markers. These loci were characterized in 48 individuals and they were tested for the ability to identify candidate migrants excha.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.February.8.1
- DOI:
- 10.4238/2013.February.8.1