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Animal Genetics   Research Article

Expression and localization of Luman/CREB3 in mouse embryos during the pre-implantation period

Authors: T.N. Mahmoud, P.F. Lin, F.L. Chen, J.H. Zhou, X.G. Wang, N. Wang, X. Li and Y.P. Jin

Luman/CREB3 is a transcription factor that is a member of the cAMP-response-element-binding protein family of basic region-leucine zipper transcription factors. This protein interacts with host cell factor 1, which also associates with the herpes simplex virus protein VP16 to induce the transcription of herpes simplex virus. Currently, the physiological f.. Read More»

Genet. Mol. Res. 14(4):
2015.October.28.20
DOI:
10.4238/2015.October.28.20
Human Genetics   Research Article

Lack of an association between TSC gene Arg904Gln polymorphisms and essential hypertension risk based on a meta-analysis

Authors: F. Zhang Y. Yang D. Hu H. Lei Y. Wang

Although there have been several studies investigating a possible association between essential hypertension and TSC gene Arg904Gln polymorphisms, the results have been inconsistent. We conducted a meta-analysis of four case-control studies (one study in Europe and three studies in Asia), including 1811 essential hypertension cases and 1381 controls. The .. Read More»

Genet. Mol. Res. 11(3):
2012.September.26.7
DOI:
10.4238/2012.September.26.7
Plant Genetics   Research Article

Isolation and characterization of 10 microsatellite loci for Pallas� long-tongued bat Glossophaga soricina (Phyllostomidae)

Authors: 3521

Glossophaga soricina is a widespread Neotropical nectarivorous bat. We characterized 10 microsatellite loci isolated from a shotgun genomic library. We analyzed tissues from wing membrane of 67 individuals collected from two populations of Central Brazil (Brasília and Alto Paraíso). The number of alleles per locus ranged from 2 to 20, and th.. Read More»

Genet. Mol. Res. 12(1):
2012.September.26.8
DOI:
10.4238/2012.September.26.8
Microbial Genetics   Research Article

Modification research on in wall of capillary copper tube with Norland optical adhesive 68 in a double stereo PCR microfluidic chip

Authors: J. Wu, F.J. Wang, C.Y. Wang, K.X. Yu, Y. Ma, T. Chen, Y.H. Li and Y. Zheng

In this study, a Norland optical adhesive 68 (NOA68) film, approximately 2.2 μm thick, was manufactured using ultraviolet solidified NOA68 in apparatus manufacturing film on the inwall of a capillary copper pipe, developed in our laboratory. The roughness of the inwall of capillary copper pipe was improved from Ra = 0.766 to 0.204 μm and the contact.. Read More»

Genet. Mol. Res. 14(4):
2015.October.28.21
DOI:
10.4238/2015.October.28.21
Animal Genetics   Research Article

Karyoevolution of the toadfish Thalassophryne nattereri (Batrachoidiformes: Batrachoididae)

Authors: G.W.W.F. Costa and W.F. Molina

The Batrachoididae includes some venomous brackish and marine fish found in the Atlantic, Indian and Pacific oceans. This family is composed of 69 species, distributed among 19 genera. Species of the genus Thalassophryne have been reported along the coast of Rio Grande do Norte (Brazil); T. nattereri has been responsible for a large number of human injuri.. Read More»

Genet. Mol. Res. 8(3):
vol8-3gmr640
DOI:
10.4238/vol8-3gmr640
Plant Genetics   Research Article

Genetic diversity of Lagerstroemia (Lythraceae) species assessed by simple sequence repeat markers

Authors: D. He Y. Liu M. Cai H.T. Pan Q.X. Zhang X.Y. Wang X.J. Wang

Lagerstroemia (crape myrtle) are famous ornamental plants with large pyramidal racemes, long flower duration, and diverse colors. However, little is known about the genetic structure and diversity of germplasm in Lagerstroemia. We genotyped 81 L. indica cultivars, five other species of Lagerstroemia, and 10 interspecific hybrids using 30 simple sequence repe.. Read More»

Genet. Mol. Res. 11(3):
2012.September.26.9
DOI:
10.4238/2012.September.26.9
Human Genetics   Research Article

Glutathione S-transferase M1 and T1 polymorphism in men with idiopathic infertility

Authors: A.C.F. Finotti1,2, R.C.P. Costa e Silva1,2, B.M. Bordin1,2, C.T.X. Silva2 and K.K.V.O. Moura1,2

Male infertility is a heterogeneous disorder, with vari­ous genetic and environmental factors that contribute to the impairment of spermatogenesis. Genetic causes are responsible for 60% of cases of idiopathic infertility. Polymorphisms of genes that encode detoxi­fying enzymes of phase II drug metabolism can modify their expres­sion or functi.. Read More»

Genet. Mol. Res. 8(3):
vol8-3gmr642
DOI:
10.4238/vol8-3gmr642
Animal Genetics   Research Article

Identification of introgressed alien chromosome segments associated with grain quality in Oryza rufipogon x MR219 advanced breeding lines using SSR markers

Authors: P. Fasahat K. Muhammad A. Abdullah R. Wickneswari

A limited backcross procedure was utilized to introgress genes associated with grain quality traits from Oryza rufipogon (Accession No. IRGC 105491), a wild rice from Malaysia, to the cultivated rice O. sativa cv. MR219, a popular high yielding Malaysian rice cultivar. A set of 10 BC2F7 progenies were selected based on the field performance and phenotypic.. Read More»

Genet. Mol. Res. 11(3):
2012.September.26.10
DOI:
10.4238/2012.September.26.10
Plant Genetics   Research Article

Assessment of the potential genotoxic risk of medicinal Tamarindus indica fruit pulp extract using in vivo assays

Authors: F.M.V. Silva1, M.F. Leite2, A.C.C. Spadaro2, S.A. Uyemura3 andE.L. Maistro4

Tamarindus indica has been used in folk medicine as an antidiabetic, a digestive aid, and a carminative, among other uses. Currently, there is no information in the toxicology literature concerning the safety of T. indica extract. We evaluated the clastogenic and/or genotoxic potential of fruit pulp extract of this plant in vivo in peripheral blood and li.. Read More»

Genet. Mol. Res. 8(3):
vol8-3gmr630
DOI:
10.4238/vol8-3gmr630
Human Genetics   Research Article

New insights into telomeric DNA sequence (TTAGGG)n location in bat chromosomes

Authors: K.C. Faria1, S.R.C. Marchesin3, P.R.L. Moreira2, M.R. Beguelini2and E. Morielle-Versute3

Molossidae species, Cynomops abrasus (2n = 34, fun­damental number, FN = 64), Eumops auripendulus (2n = 42, FN = 62), Molossus rufus (2n = 48, FN = 64), Molossops temminckii (2n = 48, FN = 64), and Nyctinomops laticaudatus (2n = 48, FN = 64), and Phyl­lostomidae species, Phyllostomus discolor (2n = 32, FN = 60), have karyotypes with different chro.. Read More»

Genet. Mol. Res. 8(3):
vol8-3gmr637
DOI:
10.4238/vol8-3gmr637