Tangeritin inhibits adipogenesis by down-regulating C/EBP�±, C/EBP�², and PPAR�³ expression in 3T3-L1 fat cells
Authors: Y.F. He, F.Y. Liu and W.X. Zhang
The treatment of obese patients is a topic investigated by an increasing number of researchers. This study aimed to elucidate the possible inhibitory effect of tangeritin on the development and function of fat cells. 3T3-L1 fat cells were grown to confluence and subjected to different concentrations of tangeritin. The most effective tangeritin inhibition .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.28.26
- DOI:
- 10.4238/2015.October.28.26
Investigation of mutations associated with pyrethroid resistance in populations of the New World Screwworm fly, Cochliomyia hominivorax (Diptera: Calliphoridae)
Authors: N.M. da Silva1,2 and A.M.L. de Azeredo-Espin1,2
Cochliomyia hominivorax larvae are known for their parasitic habit in living vertebrates, causing considerable economic losses to livestock industry. This ectoparasite has been controlled mainly by applying insecticides, but this method usually results in the selection of resistant individuals. The resistance mechanism known as knockdown resistance (kdr) .. Read More»
- Genet. Mol. Res. 8(3):
- vol8-3gmr643
- DOI:
- 10.4238/vol8-3gmr643
Molecular phylogeny of Colletotrichum (Sordariomycetes: Glomerellaceae) inferred from multiple gene sequences
Authors: H. Chen, Y. Ma, W.F. Zhang, T. Ma and H.X. Wu
The genus Colletotrichum contains many important plant pathogens mainly distributed in tropical areas. Previous studies that utilized morphology or single genes have failed to resolve the phylogenetic relationships among the species. In this study, sequences of β-tubulin, 28S ribosomal DNA, and ITS region from nine species were analyzed separately an.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.28.27
- DOI:
- 10.4238/2015.October.28.27
Mutagenic potential of water from Pelotas Creek in Rio Grande do Sul, Brazil
Authors: T.C.O. Santos1, L.F. Maciel1, K.S. Leal1, A.E.N. Bender1, T.S. Paiva1,G.L. Garcias2 and M.G. Martino-Roth1
Water resource degradation is one of mankind’s greatest worries, as it causes direct and indirect damage to the associated biota. We initiated a water monitoring study in Pelotas Creek in 2003 in order to assess the mutagenic effect of the creek’s waters. Allium cepa cells exposed to water samples and a chronically exposed macrophyte were anal.. Read More»
- Genet. Mol. Res. 8(3):
- vol8-3gmr622
- DOI:
- 10.4238/vol8-3gmr622
Genetic parameters of test-day milk yield in Guzer�¡ cattle under tropical conditions
Authors: D.A.C. Cruz, M.G.C.D. Peixoto, F.A.T. Bruneli, A.B. Bignardi and L. El Faro
The objective of this study was to estimate genetic parameters for test-day milk yield (TDMY) in Guzerá cows using random regression models. Additive and permanent environmental random effects were modeled by random regression on fourth- and fifth-order orthogonal Legendre polynomials, respectively. The residual variances were heterogeneous, with s.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.28.23
- DOI:
- 10.4238/2015.October.28.23
Effect of SERCA2a overexpression in the pericardium mediated by the AAV1 gene transfer on rapid atrial pacing in rabbits
Authors: B.N. Kuken, A.N.W.E. Aikemu, S.Y. Xiang and M.H.Y.T. Wulasihan
To study the effects of overexpression of the sarcoplasmic reticulum ATPase 2a (SERCA2a) gene on the activity and protein expression of SERCA2a after rapid atrial pacing (RAP) in New Zealand white rabbits. New Zealand white rabbits were randomly divided into a sham-operated group (group A), adeno-associated virus 1 (AAV1)/EGFP + atrial fibrillation (AF) m.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.28.24
- DOI:
- 10.4238/2015.October.28.24
Identification of earl millet cultivars using both microsatellites and enzymatic markers
Authors: R.P. Mendon�§a Neto E.V.R. Von Pinho B.L. Carvalho G.S. Pereira
The increasing number of protected and registered cultivars and problems involving seed commercialization make distinction and identification of cultivars imperative. Millet (Pennisetum glaucum), a crop species with protected cultivars in Brazil, has been the target of seed piracy. Thus, with the objective of identifying different lots with regard to origin,.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.January.7.1
- DOI:
- 10.4238/2013.January.7.1
Analysis of vaccine potential of live recombinant and inactivated wild strains of Corynebacterium pseudotuberculosis
Authors: F.A. Dorella
Caseous lymphadenitis (CLA) is a worldwide chronic disease that affects sheep and goats, whose etiological agent is Corynebacterium pseudotuberculosis. Despite all the economic losses caused by CLA, there is not much information about molecular mechanisms in the pathogenesis of this bacterium, and immune prophylaxis against the infection is not able to re.. Read More»
- Genet. Mol. Res. 8(3):
- vol8-3ta022
- DOI:
- 10.4238/vol8-3ta022
Interspecific hybridization between Tigridia pavonia and T. augusta through ovary slice culture
Authors: J.-L. PiÃ?±a-Escutia L.-M. VÃ?¡zquez-GarcÃ?Âa A.-M. Arzate-FernÃ?¡ndez
Tigridia pavonia is the most popular species in the Tigridia genus, and is currently marketed in Europe, Asia, and Australia as a landscape plant. Although it is native to Mexico, there are no breeding programs for it. In this study, we attempted to increase its flower color spectrum and growth habit by interspecific hybridization with T. augusta. Intersp.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.January.16.4
- DOI:
- 10.4238/2013.January.16.4
Relationship between serum leptin levels and non-small cell lung carcinoma: a meta-analysis
Authors: J. Du, J.C. Han, Y.J. Zhang, G.B. Qi, Y. Zhang and H.B. Li
In this study, we analyzed the association between serum leptin levels and non-small cell lung carcinoma (NSCLC). By examining English and Chinese databases, we identified potential relevant studies for statistical analysis. Human-associated case-control studies evaluating the association between serum leptin levels and NSCLC according to the random-effec.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.28.32
- DOI:
- 10.4238/2015.October.28.32