Allelic frequencies and statistical data obtained from 15 STR loci in a population of the Goi�¡s State
Authors: T.C. Vieira D.M. Silva M.A.D. Gigonzac V.L. Ferreira M.W. Gon�§alves A.D da Cruz
Due to the miscegenation of the Brazilian population, the central region of Brazil was colonized by internal migration of individuals from different origins, who contributed to the genetic diversity existing in this population. The purpose of this study was to estimate population parameters based on the allele frequencies for 15 polymorphic autosomal short-t.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.January.16.5
- DOI:
- 10.4238/2013.January.16.5
Amarelinha do Amap�¡: a carotenoid-rich cassava cultivar
Authors: N.M.A. Nassar, P.C. Fernandes, R.D. Melani and O.R. Pires J�ºnior
Eight cassava (Manihot esculenta Crantz) cultivars, of which four are indigenous to the Amazon region, along with an interspecific hybrid, were assessed for their carotenoid content. They were propagated and are maintained in the living Manihot collection at the University of Brasília. The cultivar “Amarelinha do Amapá”, whi.. Read More»
- Genet. Mol. Res. 8(3):
- vol8-3gmr625
- DOI:
- 10.4238/vol8-3gmr625
Implicating the H63D polymorphism in the HFE gene in increased incidence of solid cancers: a meta-analysis
Authors: L.L. Shen, D.Y. Gu, T.T. Zhao, C.J. Tang, Y. Xu and J.F. Chen
A number of previous studies have demonstrated that the HFE H63D polymorphism is associated with increased risk of incidence multiple types of cancer, including colorectal cancer, breast cancer, liver cancer, pancreatic cancer, and gynecological malignant tumors. However, the clinical outcomes were inconsistent. Therefore, this meta-analysis was conducted.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.28.36
- DOI:
- 10.4238/2015.October.28.36
Amplifiability of mitochondrial, microsatellite and amelogenin DNA loci from fecal samples of red brocket deer Mazama americana (Cetartiodactyla, Cervidae)
Authors: M.L. Oliveira J.M.B. Duarte
We tried to amplify mitochondrial, microsatellite and amelogenin loci in DNA from fecal samples of a wild Mazama americana population. Fifty-two deer fecal samples were collected from a 600-ha seasonal semideciduous forest fragment in a subtropical region of Brazil (21°20'S, 47°17'W), with the help of a detection dog; then, stored in ethanol and g.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.January.16.8
- DOI:
- 10.4238/2013.January.16.8
Lack of mutations of G4.5 in three families from China with noncompaction of the ventricular myocardium
Authors: Q. Liu X.F. Qi F. Ye J. Yao J. Xu
To find the underlying cause of noncompaction of the ventricular myocardium (NVM), three Chinese families with probands who presented this problem were studied. After the family members were evaluated by echocardiography, the gene G4.5 (taffazin) was scanned by sequencing. Although X-linked inheritance could not be ruled out, NVM were thought to have a va.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.January.22.3
- DOI:
- 10.4238/2013.January.22.3
Association study between Y-chromosome haplogroups and susceptibility to spermatogenic impairment in Han People from southwest China
Authors: J. Ran T.T. Han X.P. Ding X. Wei L.Y. Zhang Y.P. Zhang T.J. Li S.S. Nie L. Chen
The non-recombining portion of the Y-chromosome contains numerous polymorphisms; therefore, it is now the most informative haplotyping system with wide-ranging applications. Idiopathic azoospermia and oligospermia are among the most important causes of male infertility. Different haplogroups may have different genetic backgrounds, which may be either suscept.. Read More»
- Genet. Mol. Res. 12(1):
- 2012.January.22.4
- DOI:
- 10.4238/2012.January.22.4
Carbon source-induced changes in the physiology of the cacao pathogen Moniliophthora perniciosa (Basidiomycetes) affect mycelial morphology and secretion of necrosis-inducing proteins
Authors: F.C. Alvim1, E.M. Mattos1, C.P. Pirovani1, K. Gramacho2, C. Pungartnik1, M. Brendel1, J.C.M. Cascardo1 and M. Vincentz3
Quantitative and qualitative relationships were found between secreted proteins and their activity, and the hyphal morphology of Moniliophthora perniciosa, the causal agent of witches’ broom disease in Theobroma cacao. This fungus was grown on fermentable and non-fermentable carbon sources; significant differences in mycelial morphology we.. Read More»
- Genet. Mol. Res. 8(3):
- vol8-3gmr619
- DOI:
- 10.4238/vol8-3gmr619
Alpaca fiber growth is mediated by microRNA let-7b via down-regulation of target gene FGF5
Authors: T. Wang, Y. Zhang, H.D. Wang, Y. Shen, N. Liu, J. Cao, X.J. Yu, C.S. Dong and X.Y. He
MicroRNAs are very small endogenous RNA molecules that play a crucial role in an array of biological processes, including regulation of skin morphogenesis. The microRNA let-7b is thought to modulate animal hair growth, by binding target genes that encode growth factors. Fibroblast growth factor 5 (FGF5) has been previously reported to be involved in the i.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.28.38
- DOI:
- 10.4238/2015.October.28.38
The genetic variant rs401681C/T is associated with the risk of non-small cell lung cancer in a Chinese mainland population
Authors: H. Wang Y. Zhao J. Ma G. Zhang Y. Mu G. Qi Z. Fang L. Wang Q. Fan Z. Ma
Although lung cancer (LC) is a highly environmentally associated disease, genetic factors are also thought to play a role in this disease. In recent years, genome-wide association studies have identified various susceptible genetic regions for LC. Herein, we used high-resolution melting analysis to genotype 2 significant single nucleotide polymorphisms pr.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.January.22.5
- DOI:
- 10.4238/2013.January.22.5
Cloning, characterization and expression analysis of coagulation factor II gene in grass carp (Ctenopharyngodon idella)
Authors: B.H. Xu, K.J. Chen, Y.B. Yao, Q.L. Liu, T.Y. Xiao, J.M. Su and H.Z. Peng
Here, we characterized the structure and function of the coagulation factor II (FII) gene in grass carp and determined its role in coagulation mechanisms. The FII gene EST was obtained using a constructed splenic transcriptome database; the full-length FII gene sequence was obtained by 3' and 5' RACE. The open reading frame (ORF) of FII was cloned and the.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.28.39
- DOI:
- 10.4238/2015.October.28.39