Expressed sequence tag-PCR markers for identification of alien barley chromosome 2H in wheat
Authors: M.J. Wang H.D. Zou Z.S. Lin Y. Wu X. Chen Y.P. Yuan
We developed EST-PCR markers specific to barley chromosome 2H, for the purpose of effectively tracing alien chromosomes or chromosome parts in the wheat genetic background. The target alien chromosome 2H confers high resistance to pre-harvest sprouting, which is a worldwide natural disaster in wheat. A total of 120 primer pairs were selected by combining .. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.25.13
- DOI:
- 10.4238/2012.September.25.13
Correlation between expression and significance of �´-catenin, CD31, and VEGF of non-small cell lung cancer
Authors: X.L. Liu, L.D. Liu, S.G. Zhang, S.D. Dai, W.Y. Li and L. Zhang
We analyzed the expression and clinical significance of δ-catenin in non-small cell lung cancer (NSCLC) and investigated prognosis using human lung cancer samples. Eighty-nine NSCLC patients underwent operation between January and March 2009. There were 53 cases of squamous cell carcinoma, 31 adenocarcinoma, and 5 large cell carcinoma. δ-Caten.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.28.10
- DOI:
- 10.4238/2015.October.28.10
Case-control investigations of a DRD2 missense variant in Asian populations: more noise, less signal
Authors: P.G. Sand
--.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.25.14
- DOI:
- 10.4238/2012.September.25.14
Nucleotide variation in the mitochondrial genome provides evidence for dual routes of postglacial recolonization and genetic recombination in the northeastern brook trout (Salvelinus fontinalis)
Authors: B.L. Pilgrim R.C. Perry J.L. Barron H.D. Marshall
Levels and patterns of mitochondrial DNA (mtDNA) variation were examined to investigate the population structure and possible routes of postglacial recolonization of the worldâÂ?Â?s northernmost native populations of brook trout (Salvelinus fontinalis), which are found in Labrador, Canada. We analyzed the sequence diversity of a 1960-bp portion of the mitoc.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.26.2
- DOI:
- 10.4238/2012.September.26.2
mRNA expression profiles of calmodulin and liver receptor homolog-1 genes in chickens
Authors: Z.-C. Zhang L.-H. Xiao Y. Wang S.-Y. Chen Z.-Q. Yang X.-L. Zhao Q. Zhu Y.-P. Liu
Calmodulin (CALM), a calcium-binding protein, is expressed in the hypothalamic-pituitary-gonadal axis; it plays a pivotal role in the reproductive system by regulating gonadotropin-releasing hormone signaling. Downstream of hypothalamic-pituitary-gonadal signaling pathways, liver receptor homolog-1 (LRH-1) is involved in female gonadal hormone synthesis. .. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.26.3
- DOI:
- 10.4238/2012.September.26.3
Meta-analysis demonstrates lack of association of the hOGG1 Ser326Cys polymorphism with bladder cancer risk
Authors: D.Y. Zhong H.Y. Chu M.L. Wang L. Ma D.N. Shi Z.D. Zhang
The functional polymorphism Ser326Cys (rs1052133) in the human 8-oxoguanine DNA glycosylase (hOGG1) gene has been implicated in bladder cancer risk. However, reports of this association between the Ser326Cys polymorphism and bladder cancer risk are conflicting. In order to help clarify this relationship, we made a meta-analysis of seven case-control studi.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.26.4
- DOI:
- 10.4238/2012.September.26.4
Expression of PCA3 and PSA genes as a biomarker for differential diagnosis of nodular hyperplasia and prostate cancer
Authors: F. Fonseca Coelho, F. Loli Guimar�£es, W.L. Ribeiro Cabral, P.G. Oliveira Salles, E. Cueva Mateo, L. Mendes Nogueira e Nogueira, C.E. Corradi Fonseca and K. Braga Gomes
We evaluated the expression of the PCA3 gene in urine from patients with nodular hyperplasia/benign prostatic hyperplasia (PNH) or adenocarcinoma type prostate cancer (PCa).The study included 59 men: 22 with PCa, 26 with PNH, and 11 with no alterations (controls). Patients’ urine was collected following prostatic massage and quantified by quantitati.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.28.13
- DOI:
- 10.4238/2015.October.28.13
Bioinformatics analysis with graph-based clustering to detect gastric cancer-related pathways
Authors: P. Liu X. Wang C.H. Hu T.H. Hu
Despite a dramatic reduction in incidence and mortality rates, gastric cancer still remains one of the most common malignant tumors worldwide, especially in China. We sought to identify a set of discriminating genes that could be used for characterization and prediction of response to gastric cancer. Using bioinformatics analysis, two gastric cancer datas.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.26.5
- DOI:
- 10.4238/2012.September.26.5
Proteomic analysis of susceptibility in intestinal stromal tumors
Authors: Y.C. Yang, X. Cai, S.Y. Zhang, Z.L. Jia, T.B. Chen, L.R. Liu, J. Liu and M.C. Zhao
We analyzed the susceptibility of intestinal stromal tumors using cell culture and proteomics. Human SGC7901 gastric cells were selected and divided into a blank control group (untransfected SGC7901 cells), a negative control group [SGC7901 cells transfected with negative interference control-small interfering RNA (siRNA)], and a COOH-terminus tensin-like.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.28.16
- DOI:
- 10.4238/2015.October.28.16
Methylation-sensitive amplification polymorphism analysis of fat and muscle tissues in pigs
Authors: J.D. Ma M.Z. Li S.L. Zhou C.W. Zhou X.W. Li
DNA methylation may be involved in regulating the expression of protein-coding genes, resulting in different fat and muscle phenotypes. Using a methylation-sensitive amplified polymorphism approach, we obtained 7423 bands by selective amplification of genomic DNA from six different fat depots and two heterogeneous muscle types from Duroc/Landrace/Yorkshire c.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.26.6
- DOI:
- 10.4238/2012.September.26.6