Contribution of microsatellites markers in the clarification of the origin, genetic risk factors, and implications for conservation of Tunisian native sheep breeds
Authors: Y. Ben Sassi-Zaidy F. Maretto F. Charfi-Cheikhrouha A. Mohamed-Brahmi M. Cassandro
The genetic diversity and genetic relationship of the two main groups of African sheep, thin-tailed and fat-tailed sheep, represented by the indigenous Tunisian sheep breeds “Barbarine” (BAR, fat-tailed) and “Queue Fine de l’Ouest” (QFO, thin-tailed) were investigated. The genotypes of 110 animals belonging to these two breed.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017059
- DOI:
- 10.4238/gmr.15017059
Full-sib reciprocal recurrent selection in the maize populations Cimmyt and Piran�£o
Authors: K.S. da Cunha M.G. Pereira L.S.A. Gon�§alves A.P.C.G. Berilli E.C. de Oliveira H.C.C. Ramos A.T. do Amaral J�ºnior
We estimated the genetic gains of the 12th cycle of reciprocal recurrent selection for maize traits of agronomic interest. We used 23 ISSR molecular markers in an attempt to maximize genetic variability among and within populations based on selection of S1 progenies. To this end, 138 full-sib families were evaluated in a randomized block design in two enviro.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.25.8
- DOI:
- 10.4238/2012.September.25.8
Lack of association between the cyclooxygenase 2 -765G>C polymorphism and prostate cancer risk: a meta-analysis
Authors: Y.-Q. Feng, Y.U. Li, W.-D. Xiao, G.-X. Wang and Y.O. Li
The aim of this study was to investigate the association between the cyclooxygenase 2 (COX2) -765G>C (rs20417) polymorphism and prostate cancer (PC) risk using meta-analysis. A systematic literature search was performed using the PubMed, Embase, Cochrane Library, and Google Scholar databases by using the terms “cyclooxygenase-2/COX-2/PTGs2”.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.28.1
- DOI:
- 10.4238/2015.October.28.1
Prevalence of Plasmodium falciparum and P. vivax in an area of transmission located in Par�¡ State, Brazil, determined by amplification of mtDNA using a real-time PCR assay
Authors: C.R.T. Souza T.A.A. Carvalho R.C.G. Amaral L.S. Cunha M.G. Cunha J.F. Guerreiro
The need for a more sensitive and time-efficient assay for malaria has led to the development of molecular assays involving real-time PCR (qPCR), a procedure that has the potential to detect low levels of parasitemia, identify mixed infections, and allow for precise differentiation of species via melting curve analysis or TaqMan fluorescence-labeled probe.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.25.9
- DOI:
- 10.4238/2012.September.25.9
Protective mechanism of quercetin on acute myocardial infarction in rats
Authors: B. Li M. Yang J.W. Liu G.T. Yin
To investigate the protective mechanism of quercetin on acute myocardial infarction (AMI) rats, an AMI rat model was established by ligating the left coronary anterior descending branch. The rats were randomly divided into the model group and low- and high-dose quercetin groups. The control group comprised sham-operated rats. The rats in the low- and high.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017117
- DOI:
- 10.4238/gmr.15017117
Genetic diversity of Yersinia pestis in Brazil
Authors: M.B.M. Oliveira M.P.S. Barros V.M. Silveira-Filho M.R. Ara�ºjo-Nepomuceno V.Q. Balbino N.C. Leal A.M.P. Almeida T.C. Leal-Balbino
Plague outbreaks are occasionally reported in Brazil. Unfortunately, due to great genetic similarity, molecular subtyping of Yersinia pestis strains is difficult. Analysis of multiple-locus variable number of tandem repeats (VNTR), also known as MLVA, has been found to be a valuable tool to discriminate among strains. To check for genetic differences, str.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.25.10
- DOI:
- 10.4238/2012.September.25.10
Analysis of biochemical compounds and differentially expressed genes of the anthocyanin biosynthetic pathway in variegated peach flowers
Authors: D. Hassani, H.L. Liu, Y.N. Chen, Z.B. Wan, Q. Zhuge and S.X. Li
Variegated plants are highly valuable in the floricultural market, yet the genetic mechanism underlying this attractive phenomenon has not been completely elucidated. In this study, we identified and measured different compounds in pink and white flower petals of peach (Prunus persica) by high-performance liquid chromatography and liquid chromatography/ma.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.28.4
- DOI:
- 10.4238/2015.October.28.4
Association of CD14 G(-1145)A and C(-159)T polymorphisms with reduced risk for tuberculosis in a Chinese Han population
Authors: M.Y. Zhao Y. Xue Z.Q. Zhao F.J. Li D.P. Fan L.L. Wei X.J. Sun X. Zhang X.C. Wang Y.X. Zhang J.C. Li
Although the role of CD14 in mediating signals from Toll-like receptors to recognize Mycobacterium tuberculosis is known, how polymorphisms in this gene affect the susceptibility to develop tuberculosis are still not clear. We examined whether single nucleotide polymorphisms at positions -1145 and -159 in the promoter region of the CD14 gene are associate.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.25.11
- DOI:
- 10.4238/2012.September.25.11
NEDD4-1 and PTEN expression in keloid scarring
Authors: P.F. Sang, H. Wang, M. Wang, C. Hu, J.S. Zhang, X.J. Li and F. Zhu
Keloid scarring remains a major problem in plastic surgery. The aim of this study was to determine the expression of the PTEN tumor suppressor and NEDD4-1 genes in keloid tissue and explore their effect on the formation of such scarring. Twenty keloid patients were enrolled in the study and underwent surgical removal of keloid tissue. No patient had recei.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.28.7
- DOI:
- 10.4238/2015.October.28.7
High-accuracy splice site prediction based on sequence component and position features
Authors: J.L. Li L.F. Wang H.Y. Wang L.Y. Bai Z.M. Yuan
Identification of splice sites plays a key role in the annotation of genes. Consequently, improvement of computational prediction of splice sites would be very useful. We examined the effect of the window size and the number and position of the consensus bases with a chi-square test, and then extracted the sequence multi-scale component features and the posi.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.25.12
- DOI:
- 10.4238/2012.September.25.12