Role of MTHFR C677T polymorphism in systemic carcinogenesis, besides its role in the pathogenesis of colo-rectal carcinomas
Authors: S. Kapoor
--.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.24.2
- DOI:
- 10.4238/2012.September.24.2
Process of Bipolaris sorghicola invasion of host cells
Authors: C. Peng T.T. Ge X.L. He Y.H. Huang Z.L. Xu D.Y. Zhang H.B. Shao S.W. Guo
Target leaf spot is a sorghum leaf disease caused by Bipolaris sorghicola, a species of fungus with a global distribution. In this study, we investigated the process by which B. sorghicola invades cells of barley, onion, Arabidopsis thaliana species, and sorghum. The results showed that within 8 h of coming into contact with host cells, the hyphal ends of.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15016781
- DOI:
- 10.4238/gmr.15016781
Cloning of a phosphatidylinositol 4-kinase gene based on fiber strength transcriptome QTL mapping in the cotton species Gossypium barbadense
Authors: H.W. Liu R.F. Shi X.F. Wang Y.X. Pan G.Y. Zang Z.Y. Ma
Sea Island cotton (Gossypium barbadense) is highly valued for its superior fiber qualities, especially fiber strength. Based on a transcript-derived fragment originated from transcriptome QTL mapping, a fiber strength related candidate gene of phosphatidylinositol 4-kinase cDNA, designated as GbPI4K, was first cloned, and its expression was characterized in .. Read More»
- Genet. Mol. Res. 11(3):
- 2012.July.13.1
- DOI:
- 10.4238/2012.July.13.1
Immunomodulatory and neuroprotective effect of cryopreserved allogeneic mesenchymal stem cells on spinal cord injury in rats
Authors: I.R. Rosado, P.H. Carvalho, E.G.L. Alves, T.M. Tagushi, J.L. Carvalho, J.F. Silva, M.S.L. Lavor, K.M. Oliveira, R. Serakides, A.M. Goes, E.G. Melo
This study aimed to evaluate the immunomodulatory and neuroprotective effects of allogeneic and cryopreserved mesenchymal stem cells (MSCs) on spinal cord injury. A total of 120 rats were distributed into the following groups: negative control (NC) - without injury, positive control (PC) - with injury without treatment, and group treated with MSC (GMSC) - wi.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019555
- DOI:
- 10.4238/gmr16019555
Morphological variation of mutant sunflowers (Helianthus annuus) induced by space flight and their genetic background detection by SSR primers
Authors: J. Yang S. Shen T. Zhang G.D. Chen H. Liu X.B. Ma W.Y. Chen Z.S. Peng
After sunflower seeds were exposed to space conditions, various mutant plants were screened from the descendent plants. The morphological characters of plants changed in flower color from golden to yellow, light yellow, or even to yellowish green. The ligulate petals of the unisexual floret broadened, or became thin, while the short tubular petals of bise.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.25.6
- DOI:
- 10.4238/2012.September.25.6
Selecting soybean resistant to the cyst nematode Heterodera glycines using simple sequence repeat (microssatellite) markers
Authors: S.M.C.G. Espindola O.T. Hamawaki A.P. Oliveira C.D.L. Hamawaki R.L. Hamawaki L.M. Takahashi
The soybean cyst nematode (SCN) is a major cause of soybean yield reduction. The objective of this study was to evaluate the efficiency of marker-assisted selection to identify genotypes resistant to SCN race 3 infection, using Sat_168 and Sat-141 resistance quantitative trait loci. The experiment was carried out under greenhouse conditions, using soybean.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15016850
- DOI:
- 10.4238/gmr.15016850
Meta-analysis of epidemiological studies of association of two polymorphisms in the interleukin-10 gene promoter and colorectal cancer risk
Authors: Y.M. Zhang X.C. Zhou Z. Xu C.J. Tang
In order to make a comprehensive assessment of the potential association between two genetic variants in the IL-10 gene promoter, -1082 A>G (rs1800896) and -592 C>A (rs1800872), and colorectal cancer (CRC) risk, we conduced a meta-analysis of seven epidemiological studies, which included 1469 colorectal cancer cases and 2566 controls. Neither of the.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.25.7
- DOI:
- 10.4238/2012.September.25.7
Proteomics-based approach for identification and purification of human phosphate binding apolipoprotein from amniotic fluid
Authors: M. Alam1, M. Mahajan1, M. Raziuddin2, T.P. Singh1 and S. Yadav1
Human amniotic fluid is of both maternal and fetal origin; it protects the fetus and provides the environment for growth and development of the fetus. We used a proteomics-based approach for targeting and purifying human phosphate binding protein, a member of the DING family of proteins from amniotic fluid, using Blue Sepharose CL-6B, DEAE-Sephacel and ge.. Read More»
- Genet. Mol. Res. 8(3):
- vol8-3gmr620
- DOI:
- 10.4238/vol8-3gmr620
Effect of retinoic acid on aquaporin 3 expression in keratinocytes
Authors: F. Xing W. Liao P. Jiang W. Xu X. Jin
To explore the possible mechanism of the third-generation retinoic acid drugs (isotretinoin, acitretin, adapalene) in inducing skin and mucosa dryness and rhagades; specifically, mechanism by which these drugs influence keratinocyte cell culture models in vitro (HaCaT) and aquaporin channel (AQP3) protein expression was investigated. Isotretinoin, acitret.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15016951
- DOI:
- 10.4238/gmr.15016951
Effectiveness of muscle basal lamina carrying neural stem cells and olfactory ensheathing cells in spinal cord repair
Authors: X.W. Kang, J.L. Hu, S.K. Wang and J. Wang
We examined the effect of muscle basal lamina (MBL) with neural stem cells (NSCs) and olfactory ensheathing cells (OECs) on spinal cord injury repair. Seventy-two Sprague-Dawley rats were subjected to spinal cord hemisection and divided into 6 groups. In blank control group (group A), the ends of the spinal cord hemisection model were flushed with physiol.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.28.5
- DOI:
- 10.4238/2015.October.28.5