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Microbial Genetics   Research Article

Identification and characterization of microsatellite markers from the tropical sea cucumber, Stichopus horrens (Selenka)

Authors: J.B. Shangguan, Z.B. Li, Y. Yuan and Y.S. Huang

Tropical commercial sea cucumber Stichopus horrens is extensively distributed throughout the tropical Indo-Pacific region, and wild stocks have been severely depleted over the past decade. In this study, we used the microsatellite enrichment library of S. horrens to identify and characterize 13 microsatellite loci, including 11 polymorphic loci and 2 mono.. Read More»

Genet. Mol. Res. 14(4):
2015.October.28.18
DOI:
10.4238/2015.October.28.18
Plant Genetics   Research Article

Application of ISSR markers for verification of F1 hybrids in mungbean (Vigna radiata)

Authors: P. Khajudparn T. Prajongjai O. Poolsawat P.A. Tantasawat

Mungbean improvement via hybridization requires the identification of true F1 hybrids from controlled crosses before further generations of selfing/crossing and selection. We utilized inter-simple sequence repeat (ISSR) markers for identifying putative F1 hybrids from six cross combinations whose morphological characteristics were very similar to those of th.. Read More»

Genet. Mol. Res. 11(3):
2012.September.17.3
DOI:
10.4238/2012.September.17.3
Bioinformatics   Research Article

Interference on cytoplasmic polyadenylation element-binding proteins affects the invasion ability of glioma stem cells

Authors: H.L. Liu, J.F. Huo, Z.J. Liu and X.B. Chen

Glioma stem cells derived from primary cultures were divided into an experiment group, a control group, and a blank group and subjected to cytoplasmic polyadenilation element-binding protein (CPEBs) interference, transfection with empty vector, and normal culture, respectively, to compare their invasion abilities. Western blotting showed that siRNA-3 had .. Read More»

Genet. Mol. Res. 14(4):
2015.October.28.11
DOI:
10.4238/2015.October.28.11
Cytogenomics   Research Article

Role of mitochondrial DNA variants and copy number in diabetic atherogenesis

Authors: M.C. Chien W.T. Huang P.W. Wang C.W. Liou T.K. Lin C.J. Hsieh S.W. Weng

Hyperglycemia-induced reactive oxygen species production can cause diabetes and its complications, including atherosclerosis. The role of mitochondrial DNA variants and mitochondrial copy number in the pathogenesis of diabetic atherogenesis is not well understood. We examined 36 diabetic patients who had undergone amputation for diabetic foot and seven non-d.. Read More»

Genet. Mol. Res. 11(3):
2012.September.17.4
DOI:
10.4238/2012.September.17.4
Animal Genetics   Research Article

Biocompatibility of differently proportioned HA/PLGA/BMP-2 composite biomaterials in rabbits

Authors: H.X. Cui, J. Guo, Z. Han, Y.X. Guo and M.L. Guo

The aim of this study was to assess the histocompatibility of hydroxyapatite (HA)/poly(lactic-co-glycolic acid) (PLGA)/bone morphogenetic protein-2 (BMP-2) composite materials in rabbits. Thirty healthy New Zealand white rabbits were randomly divided into 3 groups (N = 10). HA/PLGA/BMP-2 composite materials with the HA/PLGA proportions of 1:1, 1:2, and 1:.. Read More»

Genet. Mol. Res. 14(4):
2015.October.28.12
DOI:
10.4238/2015.October.28.12
Animal Genetics   Research Article

Rapid morphological changes in populations of hybrids between Africanized and European honey bees

Authors: T.M. Francoy L.S. Gon�§alves D. De Jong

African honey bees, introduced to Brazil in 1956, rapidly dominated the previously introduced European subspecies. To better understand how hybridization between these different types of bees proceeded, we made geometric morphometric analyses of the wing venation patterns of specimens resulting from crosses made between Africanized honey bees (predominantly .. Read More»

Genet. Mol. Res. 11(3):
2012.September.17.5
DOI:
10.4238/2012.September.17.5
Animal Genetics   Research Article

Effects of beta 2 adrenergic agonists on axonal injury and mitochondrial metabolism in experimental autoimmune encephalomyelitis rats

Authors: Z.W. Zhang, X.Y. Qin, F.Y. Che, G. Xie, L. Shen and Y.Y. Bai

The primary aims of this study were to investigate mitochondrial metabolism during experimental allergic encephalomyelitis (EAE) animal model axonal injury and to determine the correlation among neurological function scores, pathological changes, and the activities of the BB isoenzyme of creatine kinase (CK-BB), catalase (CAT), and calpain in the brain ti.. Read More»

Genet. Mol. Res. 14(4):
2015.October.28.17
DOI:
10.4238/2015.October.28.17
Animal Genetics   Research Article

Phenotypic and molecular characterization of CTX-M-14 extended-spectrum �²-lactamase and plasmid-mediated ACT-like AmpC �²-lactamase produced by Klebsiella pneumoniae isolates from chickens in Henan Province, China

Authors: H. Wu B.-G. Liu J.-H. Liu Y.-S. Pan L. Yuan G.-Z. Hu

Extended-spectrum Ã?²-lactamases (ESBLs) and AmpC Ã?²-lactamases produced by a clinical isolate of Klebsiella pneumoniae from chickens were detected with confirmatory phenotypic tests of the Clinical and Laboratory Standards Institute. The minimum inhibitory concentrations of 18 antibacterial drugs against K. pneumoniae were determined by the 2-fold microd.. Read More»

Genet. Mol. Res. 11(3):
2012.September.24.1
DOI:
10.4238/2012.September.24.1
Plant Genetics   Research Article

Path analysis and canonical correlations for indirect selection of Jatropha genotypes with higher oil yield

Authors: L.A. Silva, L.A. Peixoto, P.E. Teodoro, E.V. Rodrigues, B.G. Laviola, L.L. Bhering

Jatropha is a species with great potential for biodiesel production, and the knowledge on how the main agronomic traits are correlated will contribute to its improvement. Therefore, the objectives of this study were to estimate the genetic parameters of the traits: plant height at 12 and 40 months, canopy projection on the row.. Read More»

Genet. Mol. Res. 16(1):
gmr16019562
DOI:
10.4238/gmr16019562
Human Genetics   Research Article

Occurrence of mutations in loci linked to Y chromosome in the offspring born to individuals exposed to ionizing radiation

Authors: J.T. Arruda

In September 1987, in Goiânia, GO, Brazil, one of the most serious radiological accidents occurred at a radiotherapy unit involving a source of cesium-137. An area of 2000 m2 was contaminated and 249 people were exposed, both externally and internally, to substantial doses of ionizing radiation, resulting in four fatalities due to acute radiation sy.. Read More»

Genet. Mol. Res. 8(3):
vol8-3ta021
DOI:
10.4238/vol8-3ta021