GSTM1 polymorphism in patients with primary open-angle glaucoma
Authors: A.M. Barbosa A.B. Frare N.B. Costa R.E. Silva K.K.V.O. Moura
Primary open-angle glaucoma (POAG) is characterized by loss of retinal ganglion cells, optic nerve damage and irreversible loss of visual field. Glaucoma is the second leading cause of blindness worldwide. It was estimated that in 2010 there were about 60.5 million glaucoma cases worldwide; among these patients, 4.5 million will become bilaterally blind. .. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.12.8
- DOI:
- 10.4238/2012.September.12.8
Development and characterization of 22 polymorphic microsatellite markers for the balloon flower Platycodon grandiflorum (Campanulaceae)
Authors: J.Y. Song G.-A. Lee M.-S. Yoon K.-H. Ma Y.-M. Choi J.-R. Lee H.-J. Park M.-C. Lee
The balloon flower (Platycodon grandiflorum A. DC.) is a perennial flowering plant of the Campanulaceae family; it is the only member of the genus Platycodon. Information on the genetic diversity of balloon flower populations is of great importance for the conservation and germplasm utilization of this flowering plant. Twenty-two polymorphic microsatellite l.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.12.9
- DOI:
- 10.4238/2012.September.12.9
Diallel cross analysis of plesiomorphic traits in Triticum aestivum L. genotypes
Authors: M. Shehzad, S.B. Hussain, M.K. Qureshi, M. Akbar, M. Javed1, H.M. Imran and S.A. Manzoor
We conducted a 5 x 5 complete diallel cross experiment in bread wheat (Triticum aestivum) with the genotypes 6309, Chkwal-50, Dhrabi, Bhkhar-02, and FS-08. Our objective was to evaluate the type of gene action and the general and specific combining abilities required for various morphological traits in wheat. The results of analysis of variance revealed h.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.28.9
- DOI:
- 10.4238/2015.October.28.9
Molecular characterization of sour orange (Citrus aurantium) accessions and their relatives using SSR and SRAP markers
Authors: I. Polat Y.A. Ka�§ar T. Yesiloglu A. Uzun O. Tuzcu O. Gulsen M. Incesu G. Kafa E. Turgutoglu S. Anil
Citrus production with its many varieties is of importance since it provides economically important products for Turkish exports. Sour orange is a rootstock commonly used for propagating the different scion varieties. Knowledge of the genetic diversity of the rootstock accessions would be useful in order to improve citrus breeding programs. We studied geneti.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.12.10
- DOI:
- 10.4238/2012.September.12.10
Blockade of S100A3 activity inhibits murine hair growth
Authors: W. Guan, Q. Deng, X.L. Yu, Y.S. Yuan, J. Gao, J.J. Li, L. Zhou, P. Xia, G.Y.Q. Han, W. Han and Y. Yu
Using mouse gene expression microarray analysis, we obtained dynamic expression profiles of the whole genome in a depilation-induced hair growth mouse model. S100A3 expression increased during the anagen phase and returned to normal during the telogen phase. The effects of S100A3 blockade on the hair growth cycle were examined in mice after subcutaneous i.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.28.14
- DOI:
- 10.4238/2015.October.28.14
Identification of quantitative trait loci for blast resistance in BC2F3 and BC2F5 advanced backcross families of rice
Authors: H.A. Rahim M.A.R. Bhuiyan L.S. Lim K.K. Sabu A. Saad M. Azhar R. Wickneswari
Advanced backcross families derived from Oryza sativa cv MR219/O. rufipogon IRGC105491 were utilized for identification of quantitative trait loci (QTL) for blast resistance using simple sequence repeat markers. Two hundred and sixty-one BC2F3 families were used to construct a linkage map, using 87 markers, which covered 2375.2 cM of 12 rice chromosomes, wit.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.12.11
- DOI:
- 10.4238/2012.September.12.11
Dithranol downregulates expression of Id1 mRNA in human keratinocytes in vitro
Authors: C. Ronpirin T. Tencomnao
The precise causes of psoriasis, a chronic skin disorder characterized by hyperproliferation of keratinocytes and incomplete keratinization, are unclear. It is known that expression of helix-loop-helix transcription factor Id1, which functions as an inhibitor of differentiation, is upregulated in psoriatic skin. We investigated the effect of the antipsori.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.12.12
- DOI:
- 10.4238/2012.September.12.12
Analysis of genetic traits for drought tolerance in maize
Authors: R.W. Muhammad, A. Qayyum, A. Hamza, M.Q. Ahmad, N.S. Naseer, S. Liaqat, B. Ahmad, W. Malik and E. Noor
Fifty-four genotypes of maize were crossed and evaluated in the field during the crop season in February 2012 under both normal and water stress conditions. To identify the major parameters responsible for variation among genotypes, single linkage cluster analysis and principle component analysis (PCA) were carried out. Thirteen characters were studied. T.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.28.15
- DOI:
- 10.4238/2015.October.28.15
Overexpression of the cytochrome P450 monooxygenase (cyp71av1) and cytochrome P450 reductase (cpr) genes increased artemisinin content in Artemisia annua (Asteraceae)
Authors: Q. Shen Y.F. Chen T. Wang S.Y. Wu X. Lu L. Zhang F.Y. Zhang W.M. Jiang G.F. Wang K.X. Tang
Finding an efficient and affordable treatment against malaria is still a challenge for medicine. Artemisinin is an effective anti-malarial drug isolated from Artemisia annua. However, the artemisinin content of A. annua is very low. We used transgenic technology to increase the artemisinin content of A. annua by overexpressing cytochrome P450 monooxygenase (.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.12.13
- DOI:
- 10.4238/2012.September.12.13
Transcript profiling of expressed sequence tags from semimembranosus muscle of commercial and naturalized pig breeds
Authors: C.S. Nascimento J.O. Peixoto L.L. Verardo C.F. Campos M.M.C. Weller V.R. Faria M.E. Botelho M.F. Martins M.A. Machado F.F. Silva P.S. Lopes S.E.F. Guimar�£es
Sacbrood disease, an affliction of honey bees (Apis mellifera) characterized by brood that fails to pupate and subsequently dies, is an important threat to honey bee health. The disease is caused by the sacbrood virus (SBV), a positive-, single-stranded RNA virus in the order Picornavirales. Because of the economic importance of honey bees for both pollinati.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.June.15.1
- DOI:
- 10.4238/2012.June.15.1