Cloning and prokaryotic expression of rat homolog of Serpina3n and its expression change during liver regeneration
Authors: G.P. Wang X.S. Zhang Y.H. Li J.L. Zheng C.Z. Tang W.X. Zhang
A strikingly upregulated expressed sequence tag was screened from regenerating rat liver at 8 h in a 0-4-8-12 h short-interval successive partial hepatectomy model from a previous study. In the present study, a full-length open reading frame (ORF) corresponding to this expressed sequence tag was predicted through electronic cloning and was subsequently cl.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.3.6
- DOI:
- 10.4238/2012.September.3.6
Sequence and phylogenetic analyses of the M and N genes of porcine epidemic diarrhea virus (PEDV) strains in Anhui Province, China
Authors: P. Sun, C.Y. Gu, Y.Y. Ding, J.H. Wei, Z.J. Yin, Z.Y. Geng and Y. Li
To assess the homology and phylogenetic relationship between porcine epidemic diarrhea virus (PEDV) Anhui strains and other PEDV strains, molecular homology and phylogenetic analyses of Anhui PEDV field strains were compared with those of reference strains. The results revealed that the M and N genes of PEDV were 681 and 1326 bp long, respectively. The nu.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.28.2
- DOI:
- 10.4238/2015.October.28.2
Genetic distances between popcorn populations based on molecular markers and correlations with heterosis estimates made by diallel analysis of hybrids
Authors: R.E.F. Munhoz1, A.J. Prioli1, A.T. Amaral J�ºnior2, C.A. Scapim1 and G.A. Simon1
Diallel analysis was used to obtain information on combining ability, heterosis, estimates of genetic distances by random amplified polymorphic DNA (RAPD) and on their correlations with heterosis, for the popcorn varieties RS 20, UNB2, CMS 43, CMS 42, Zélia, UEM J1, UEM M2, Beija-Flor, and Viçosa, which were crossed to obtain all possib.. Read More»
- Genet. Mol. Res. 8(3):
- vol8-3gmr592
- DOI:
- 10.4238/vol8-3gmr592
Gene expression and enzymatic activity of pectin methylesterase during fruit development and ripening in Coffea arabica L.
Authors: S.M.B. Ca�§�£o T.F. Leite I.G.F. Budzinski T.B. dos Santos M.B.S. Scholz V. Carpentieri-Pipolo D.S. Domingues L.G.E. Vieira L.F.P. Pereira
Coffee quality is directly related to the harvest and post harvest conditions. Non-uniform maturation of coffee fruits, combined with inadequate harvest, negatively affects the final quality of the product. Pectin methylesterase (PME) plays an important role in fruit softening due to the hydrolysis of methylester groups in cell wall pectins. In order to c.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.3.7
- DOI:
- 10.4238/2012.September.3.7
Patterns of genetic diversity and population structure of the threatened Houbara and Macqueen�s bustards as revealed by microsatellite markers
Authors: A. Korrida S. Jadallah F. Chbel A. Amin-Alami M. Ahra S. Aggrey
The Houbara bustard (Chlamydotis undulata) is a threatened avian species that is rapidly declining throughout its range, especially in North Africa, Asia and the Canary Islands. We examined the population structure and genetic variation for the three Houbara subspecies C. undulata undulata, C. u. fuertaventurae and C. u. macqueenii. A total of 266 birds from.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.12.4
- DOI:
- 10.4238/2012.September.12.4
Significant interaction of APOE rs4420638 polymorphism with HDL-C and APOA-I levels in coronary heart disease in Han Chinese men
Authors: Y. Huang, H.D. Ye, X. Gao, S. Nie, Q.X. Hong, H.H. Ji, J. Sun, S.J. Zhou, B. Fei, K.Q. Li, J.K. Zhao, Z.P. Wang, M.Q. Xu and S.W. Duan
Apolipoprotein E (APOE) is recognized for its importance in lipoprotein metabolism and cardiovascular disease. We evaluated the association between APOE rs4420638 genotypes and circulating lipid concentrations along with the risk of coronary heart disease (CHD). We conducted a case-control study involving 1508 individuals to investigate the contribution o.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.28.3
- DOI:
- 10.4238/2015.October.28.3
Selection pressures have driven population differentiation of domesticated and wild common carp (Cyprinus carpio L.)
Authors: L.H. Xu C.H. Wang J. Wang Z.J. Dong Y.Q. Ma X.X. Yang
Selection pressures are the principle evolutionary forces for the genetic differentiation of populations. Recent changes in selection pressures on mitochondrial DNA and microsatellite have been described in a wide variety of organisms. The common carp (Cyprinus carpio) has experienced strong selection pressure, in particular artificial selection, during i.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.12.5
- DOI:
- 10.4238/2012.September.12.5
Influence of gossypol acetic acid on the growth of human adenoid cystic carcinoma ACC-M cells and the expression of DNA methyltransferase 1
Authors: Y. Wu, Y.-N. Wei, W.-Y. Yue, W.-F. Chen and S. Fu
We investigated the effects of gossypol acetic acid (GAA) on the proliferation, apoptosis, and expression of DNA methyltransferase 1 (DNMT1) mRNA in human adenoid cystic carcinoma (ACC-M) cells in vitro. The proliferation and apoptosis of ACC-M cells after treatment with different concentrations of GAA were detected using Cell Counting Kit-8 and flow cyto.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.28.6
- DOI:
- 10.4238/2015.October.28.6
Variable expressivity of osteogenesis imperfecta in a Brazilian family due to p.G1079S mutation in the COL1A1 gene
Authors: M.V.D. Moraes M. Milanez B.V.P. Almada V. Sipolatti M.R.G.O. Rebou�§as V.R.R. Nunes A.N. Akel Jr. M. Zatz F.I.V. Errera I.D. Louro F. Paula
Osteogenesis imperfecta (OI) is a Mendelian disease with genetic heterogeneity characterized by bone fragility, recurrent fractures, blue sclerae, and short stature, caused mostly by mutations in COL1A1 or COL1A2 genes, which encode the pro-α1(I) and pro-α2(I) chains of type I collagen, respectively. A Brazilian family that showed variable exp.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.12.7
- DOI:
- 10.4238/2012.September.12.7
Identification of molecular markers related to human alveolar bone cells and pathway analysis in diabetic patients
Authors: X. Sun, Q.H. Ren, L. Bai and Q. Feng
Alveolar bone osteoblasts are widely used in dental and related research. They are easily affected by systemic diseases such as diabetes. However, the mechanism of diabetes-induced alveolar bone absorption remains unclear. This study systematically explored the changes in human alveolar bone cell-related gene expression and biological pathways, which may .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.28.8
- DOI:
- 10.4238/2015.October.28.8