Molecular characterization, expression, polymorphism of NR5A2 and its relationship with litter size in Hu sheep
Authors: Y.X. Li, J. Zhang, Y. Qian, C.H. Meng, H.L. Wang, X.J. Tao, S. Zhong, S.X. Cao and Q.F. Li
NR5A2 has been implicated in processes as diverse as steroidogenesis, cellular proliferation, ovarian follicular development, ovulation, and fertility in mammals. However, data about the relationship between NR5A2 and prolificacy in mammals are lacking. In the present study, we identified and characterized NR5A2 of Hu sheep, a.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.19.20
- DOI:
- 10.4238/2015.October.19.20
Evaluation of grain yield in sorghum hybrids under water stress
Authors: C.B. Menezes, D.C. Saldanha, C.V. Santos, L.C. Andrade, M.P. Mingote J�ºlio, A.F. Portugal and F.D. Tardin
Sorghum grain yield can be significantly affected by climatic changes, especially drought and high temperature. The purpose of this study was to evaluate hybrids of grain sorghum grown under normal irrigation conditions or water stress in order to select those likely to be more tolerant of drought. Forty-nine hybrids were grow.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.19.11
- DOI:
- 10.4238/2015.October.19.11
MC1R, KIT, IGF2, and NR6A1 as markers for genetic differentiation in Thai native, wild boars, and Duroc and Chinese Meishan pigs
Authors: P. Klomtong, K. Chaweewan, Y. Phasuk and M. Duangjinda
Mutations in melanocortin 1 receptor (MC1R) gene and v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (KIT) gene have been shown to affect coat color patterns in pigs. Additional functional marker genes, such as insulin like growth factor-2 (IGF2) and orphan nuclear receptor, germ cell nuclear factor (NR6A1), have.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.19.16
- DOI:
- 10.4238/2015.October.19.16
Real-time PCR evaluation of cell-free DNA subjected to various storage and shipping conditions
Authors: Q. Wang, Y. Cai, P. Brady and J.R. Vermeesch
In this study, we attempted to explore the factors affecting the yield of cell-free fetal DNA (cffDNA) obtained from maternal blood samples, including the use of different types of collection tubes, the interval between sample processing, and sample shipping under extreme weather conditions. Blood samples were drawn into K3EDT.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.19.23
- DOI:
- 10.4238/2015.October.19.23
Arm-Gal4 inheritance influences development and lifespan in Drosophila melanogaster
Authors: F.A. Slade and B.E. Staveley
The UAS-Gal4 ectopic expression system is a widely used and highly valued tool that allows specific gene expression in Drosophila melanogaster. Yeast transcription factor Gal4 can be directed using D. melanogaster transcriptional control elements, and is often assumed to have little effect on the organism. By evaluation of the.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.19.22
- DOI:
- 10.4238/2015.October.19.22
Segment-specific targeting via RNA interference mediates down-regulation of OPN expression in hepatocellular carcinoma cells
Authors: F. Lin1*, C.M. Huang2*, J. Cao1, Z.H. Pei1, W.L. Gu1, S.F. Fan1, K.P. Li1 and C.M. Lin1
Osteopontin (OPN) plays an important role in the metastasis and recurrence of tumors after resection of hepatocellular carcinoma (HCC). In this study, the down-regulation effect on OPN expression in HCC cells of RNA interference (RNAi) molecules designed to target different segments of OPN was investigated to identify a more effective site for OPN knockdo.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.18.6
- DOI:
- 10.4238/2015.November.18.6
Cloning, identification, and bioinformatics analysis of a putative aquaporin TsAQP from Trichinella spiralis
Authors: J.M. Cui, N.Z. Zhang, W.H. Li, H.B. Yan and B.Q. Fu
Vaccination as a preventative strategy against Trichinella spiralis infection is an ongoing effort, although no ideal vaccine candidates have been identified until now. Identification of more effective antigens that have a role in essential life stages of the parasite and that may be effective vaccine candidates is therefore o.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.19.14
- DOI:
- 10.4238/2015.October.19.14
Effect of luteolin on gene expression in mouse H22 hepatoma cells
Authors: J.X. Niu1, H.P. Guo2, H.M. Gan3, L.D. Bao4, J.J. Ren1
The purpose of our study was to observe the effects of luteolin on the expression of the genes ICAM-1, LFA-3, and PCNA in H22 hepatoma tissue. Sixty ICR (Institute of Cancer Research) mice with H22 hepatoma were randomly divided into five groups: a normal saline control group, low-, medium-, and high-dose luteolin groups, and a cyclophosphamide group. The.. Read More»
- Genet. Mol. Res. 14(4):
Clinical image and pathology of hypertrophic cranial pachymeningitis
Authors: C.H. Shi, S.T. Niu and Z.Q. Zhang
The objective of this study was to examine the clinical findings, magnetic resonance imaging (MRI), pathological features, and treatment experiments of patients with hypertrophic cranial pachymeningitis (HCP). The clinical findings, MRI, and pathological appearances of 9 patients with HCP were analyzed retrospectively. The thickened dura mater was markedl.. Read More»
- Genet. Mol. Res. 13(4):
- 2014.December.12.11
- DOI:
- 10.4238/2014.December.12.11
PPAR�± signal pathway gene expression is associated with fatty acid content in yak and cattle longissimus dorsi muscle
Authors: W. Qin, C.N. Liang, X. Guo, M. Chu, J. Pei, P.J. Bao, X.Y. Wu, T.K. Li and P. Yan
ntramuscular fatty acid (FA) is related to meat qualities such as juiciness, tenderness, palatability, and shear force. PPARα plays an important role in lipid metabolism in the liver and skeletal muscle. This study investigated FA composition in yaks and cattle, in order to ascertain whether a correlation between PPARα signal pathway genes as .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.18.9
- DOI:
- 10.4238/2015.November.18.9