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Plant Genetics   Research Article

Induction and identification of Stylosanthes guianensis tetraploids

Authors: F.H. Wu, X.D. Yu, N.S. Zhuang, G.D. Liu and J.P. Liu

Stylosanthes guianensis is an elite and important forage legume species, which is extensively cultivated in tropical areas. Polyploid breeding via exposure to colchicine is a conventional and practical method to improve varieties of S. guianensis. Terminal buds of S. guianensis Reyan No.5 seedlings were treated with different .. Read More»

Genet. Mol. Res. 14(4):
2015.October.19.13
DOI:
10.4238/2015.October.19.13
Plant Genetics   Research Article

Assessing the genotoxicities of sparteine and compounds isolated from Lupinus mexicanus and L. montanus seeds by using comet assay

Authors: M.R. Silva, C.M. Alvarez, P.M. Garc�­a and M.A. Ruiz

The genus Lupinus is widely distributed. Its seeds are used for animal and human food, and Lupinus possesses pharmacological potential because of its high content of quinolizidine alkaloids and flavonoids; however, there is little available information about its genotoxicity. We used the comet assay and staminal nuclei of Tradescantia (clone 4430) to eval.. Read More»

Genet. Mol. Res. 13(4):
2014.December.12.12
DOI:
10.4238/2014.December.12.12
Human Genetics   Research Article

Alleviation of streptozotocin-induced diabetes in nude mice by stem cells derived from human first trimester umbilical cord

Authors: M. Cao, J.B. Zhang, D.D. Dong, Y. Mou, K. Li, J. Fang, Z.Y. Wang, C. Chen, J. Zhao and S.M. Yie

Cells isolated from human first trimester umbilical cord perivascular layer (hFTM-PV) tissues display the pluripotent characteristics of stem cells. In this study, we examined whether hFTM-PV cells can differentiate into islet-like clusters (ILCs) in vitro, and whether transplantation of the hFTM-PV cells with and without diff.. Read More»

Genet. Mol. Res. 14(4):
2015.October.16.18
DOI:
10.4238/2015.October.16.18
Plant Genetics   Research Article

Comparative analysis of phylogenetic relationships, morphologies, and pathogenicities among Curvularia lunata isolates from maize in China

Authors: T. Liu, F.Z. Zhao, Y.Y. Wang, J.M. Hou, L.Z. Liu, Y.Q. Shen, Z. Liu, H.T. Zhang and Y.H. Zuo

To understand the effects of disease-resistant maize varieties and new cropping systems on the population of Curvularia lunata, 52 isolates of C. lunata were collected in China from 2011 to 2013. The isolates were analyzed in terms of phylogenetic relationships, morphology, and pathogenicity. Phylogenetic analysis showed that .. Read More»

Genet. Mol. Res. 14(4):
2015.October.16.21
DOI:
10.4238/2015.October.16.21
Human Genetics   Research Article

Association between a functional genetic polymorphism (rs2230199) and age-related macular degeneration risk: a meta-analysis

Authors: M.X. Zhang, X.F. Zhao, Y.C. Ren, T.T. Geng, H. Yang, T. Feng, T.B. Jin and C. Chen

The association between the rs2230199 C>G single nucleotide polymorphism (SNP) in complement component 3 and age-related macular degeneration (AMD) risk has been examined extensively but the results are not consistent among studies. The aim of this study was to perform a meta-analysis of all available studies on this SNP in.. Read More»

Genet. Mol. Res. 14(4):
2015.October.16.24
DOI:
10.4238/2015.October.16.24
Human Genetics   Original Articles

Nineteen polymorphic microsatellite markers developed for Trachinotus ovatus

Authors: Z.Z. Xie, M.W. Huang, W. Xu, C. Peng, J.N. He, Z.N. Meng, Y. Zhang, S.S. Li and H.R. Lin

To evaluate the population genetic diversity of the ovate pompano, we isolated and characterized 19 microsatellite markers using a (CA)13-enriched genomic library. Polymorphism was assessed in 30 individuals from a single population collected from the Daya Bay Aquaculture Center, Guangdong, China. The number of alleles per locus ranged from 2 to 18 with a.. Read More»

Genet. Mol. Res. 13(4):
2014.December.12.13
DOI:
10.4238/2014.December.12.13
Human Genetics   Research Article

Association between the ERCC2 rs13181 polymorphism and the risk of glioma: a meta-analysis

Authors: T.L. Jia, H.J. Wu, H.B. Wang, W.B. Ma and B. Xing

Several studies have focused on the association between the ERCC2 rs13181 polymorphism and glioma risk, but the results were inconclusive. We aimed to conduct a meta-analysis to investigate the role of ERCC2 rs13181 on the risk of glioma. We searched and collated the relevant studies in both Chinese and English through the Pub.. Read More»

Genet. Mol. Res. 14(4):
2015.October.19.1
DOI:
10.4238/2015.October.19.1
Human Genetics   Research Article

Presence of Mycobacterium leprae DNA and PGL-1 antigen in household contacts of leprosy patients from a hyperendemic area in Brazil

Authors: J.D. Pinho1, P.M.S. Rivas1, M.B.P. Mendes1, R.E.P. Soares1, G.C. Costa2,F.R.F. Nascimento2, M.F.L. Paiva3, D.M.C. Aquino4, I.A. Figueireido5,A.M. Santos3 and S.R.F. Pereira1

Leprosy is a highly infectious disease endemic to underdevel­oped countries. In Maranhão State, Northeastern Brazil, the hyperendemic rate of 56.11 cases/100,000 inhabitants increased the necessity of better understanding the epidemiological profile of this population, particularly re­garding efficient methods for evaluating individuals res.. Read More»

Genet. Mol. Res. 14(4):
2015.November.18.10
DOI:
10.4238/2015.November.18.10
Animal Genetics   Research Article

Genetic parameters for milk production traits and breeding goals for Gir dairy cattle in Brazil

Authors: M.A. Prata, L.E. Faro, H.L. Moreira, R.S. Verneque, A.E. Vercesi Filho, M.G.C.D. Peixoto and V.L. Cardoso

To implement an animal breeding program, it is important to define the production circumstances of the animals of interest to determine which traits of economic interest will be selected for the breeding goal. The present study defined breeding goals and proposed selection indices for milk production and quality traits of Gir .. Read More»

Genet. Mol. Res. 14(4):
2015.October.19.2
DOI:
10.4238/2015.October.19.2
Plant Genetics   Research Article

Quantitative trait locus analysis for kernel width using maize recombinant inbred lines

Authors: G.Q. Hui1, G.Q. Wen2, X.H. Liu2, H.P. Yang1, Q. Luo1, H.X. Song3, L. Wen3,Y. Sun4 and H.M. Zhang1,5

Maize (Zea mays L.) kernel width is one of the most important traits that is related to yield and appearance. To understand its genetic mechanisms more clearly, a recombinant inbred line (RIL) segregation population consisting of 239 RILs was used for quantitative trait locus (QTL) mapping for kernel width. We found four QTLs on chromosomes 3 (one), 5 (tw.. Read More»

Genet. Mol. Res. 14(4):
2015.November.18.12
DOI:
10.4238/2015.November.18.12