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Microbial Genetics   Research Article
Differential expression of genes associated with low-level vancomycin resistance in Staphylococcus aureus

Authors: Auttawit Sirichoat, Viraphong Lulitanond, Sujintana Wongthong, Aroonwadee Chanawong, Ratree Tavichakorntrakool and Aroonlug Lulitanond

Heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA) and vancomycin-intermediate S. aureus (VISA) have been associated with treatment failure, and hVISA cannot be detected by routine disc diffusion test. Currently, there is no specific genetic marker for detection of these strains. The aim of the current study was to inves.. Read More»

Genet. Mol. Res. 18(2):

Animal Genetics   Research Article
Development and characterization of microsatellite molecular markers for the eye mask frog Batrachyla taeniata (Girard, 1855)

Authors: Ingrid Cisternas-Medina, Juan Carlos Ortiz and Sandra Ferrada-Fuentes

Batrachyla taeniata (Batrachylidae) is a small frog from Chile and Argentina with a distributional range that spans more than 1500 km. However, their populations are threatened due to the change in land use, deforestation, and human settlements. Through massive sequencing runs in ION Torrent PGM, was built DNA fragment library, from which we fina.. Read More»

Genet. Mol. Res. 18(2):

Medical Genetics   Research Article
Expression of HCN and sodium channels in murine model of Type I diabetes

Authors: Anantha Maharasi Rama Krishnan and Kavitha Sankaranarayanan

Pancreatic apoptosis is an important event in the pathogenesis of Type 1 Diabetes. It is characterized by secretion and binding of inflammatory cytokines to the pancreatic islets, that activate downstream signaling mechanism. These signaling mechanisms finally increase intracellular calcium level and that lead to the activation of apoptotic pathways. Ion .. Read More»

Genet. Mol. Res. 18(2):

Plant Genetics   Research Article
Dynamism of the breeding program for irrigated rice in Southeast Brazil

Authors: A.C. Silva Júnior, V.Q. Carneiro, I.G. Santos, W.G Costa, R.D.S. Rosado, C.D. Cruz and P.C. Soares

The estimation of the genotypic replacement rate is aimed at evaluating the performance of breeding programs. Thus, the objective of this study was to evaluate the dynamics of the genetic improvement program of flooded rice, developed in Minas Gerais, during the period from 1993 to 2016. We evaluated 210 lines in three environments between 1993 and 2016, .. Read More»

Genet. Mol. Res. 18(2):

Animal Genetics   Research Article
Protective effect of Vitamin D on Cardiac Mitochondrial Apoptotic pathway in Rats fed with high fat diet

Authors: Khadeejah Mesaid Al-Solami, Zienab Alrefaie, Hossam Awad

Background: Both diet quality and vitamin D status are important factors associated with many cardiovascular risk factors. Cardiac mitochondrial pathway of apoptosis has been associated with those factors. The current work aimed to assess the effect of chronic consumption of high fat diet (HFD) on the cardiac markers of mitochondrial path.. Read More»

Genet. Mol. Res. 18(2):

Human Genetics   Research Article
Synonymous Variant of ACE Gene (rs4343) is Coupled with Early Age at Onset and Diminished Diabetic Duration in South Indian Diabetic Nephropathy Patients

Authors: S. Babi Heera, Umme Najiya Mahwish, Fazul Rahman, Sayeeduddin S, Sree Bhushan Raju , Parveen Jahan

Diabetic nephropathy (T2DN) is a major micro vascular complication associated with type-2 diabetes (T2DM). Abnormally active Renin Angiotensin System pathway is shown to influence the development of T2DN and the inter-individual variation with respect to ACE levels, a key enzyme in this pathway partly dependent on the genetic variants of ACE.. Read More»

Genet. Mol. Res. 18(2):

Plant Genetics   Research Article
Digital image analysis to quantify genetic divergence in passion fruit seeds

Authors: Leandro Rafael Fachi, Willian Krause, Henrique Duarte Vieira, Dejânia Vieira de Araújo, Petterson Baptista da Luz, Alexandre Pio Viana

Phenotyping through digital images has been used to evaluate morphological characteristics of seeds, providing fast, accurate results. The objective of this work was to estimate the genetic divergence among full-sibling families of passion fruit through morphophysiological characteristics of seeds using the Ward-MLM method. Seeds of 98 full-sibling famili.. Read More»

Genet. Mol. Res. 18(2):

Human Genetics   Research Article
Adrenomedullin gene polymorphisms (rs4399321A/G and rs4910118C/T) in pregnancy related disorder: Preeclampsia

Authors: Goske Deepthi, Komaravalli Prasanna Latha, Vital Usharani, Prof. P. Fazul Rahman, Parveen Jahan

Preeclampsia (PE), a pregnancy specific vascular disorder which is characterized by hypertension and proteinuria is a leading cause of maternal, fetal/neonatal morbidity and mortality affecting 5-14% of pregnancies. PE is a multifactorial disorder associated with poor placentation, placental hypoxia, poor angiogenesis and excessive maternal inflammation. .. Read More»

Genet. Mol. Res. 18(2):