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Human Genetics   Research Article
Genetic Polymorphism in Endometriosis: Trends in Scientific Production

Authors: Maria Gabriela Machado Junqueira, Amanda Fernandes Costa, Felipe de Ara�ºjo Nascimento, K�¡tia Karina Verolli de Oliveira Moura, Fl�¡via Melo Rodrigues

Endometriosis is characterized by the presence of endometrial tissue located outside the uterine cavity. The prevalence is around 6 to 10%. Regarding etiopathogenesis, several theories are accepted, but alterations in the molecular biology of the endometrium seem to be fundamental for the development of endometriosis. Women wi.. Read More»

Genet. Mol. Res. 17(1): gmr16039891

DOI: 10.4238/gmr16039891

Plant Genetics   Research Article
Adaptability and stability of cotton cultivars (Gossypium hirsutum L. race latifolium H.) using factor analytic model

Authors: J. J. Nuvunga, L. A. Oliveira, C. P. Silva, A. K. A. Pamplona, A. Q. Silva, E. G. Moura, M. P. Maleia, M. Balestre

To build up efficient strategies in plant breeding programs, it is requested a certain level of knowledge about the genotype–by-environments interaction (GEI) effects over the crop to be improved. One efficient way to gather this information is using linear mixed models using a parsimonious structure of GEI pattern such .. Read More»

Genet. Mol. Res. 17(1): gmr16039890

DOI: 10.4238/gmr16039890

Human Genetics   Research Article
Predominance of the A allele but no association of the KCNJ11 rs5219 E23K polymorphism with Type 2 Diabetes in a Nigerian population

Authors: Godwill Azeh Engwa, Friday Nweke Nwalo, Chosen E. Obi, Christie Onyia, Opeolu Oyejide Ojo Wilfred Fon Mbacham, Benjamin Ewa Ubi

Though the rs5219 E23K variant of the KCNJ11 gene is commonly known to be associated with Type 2 diabetes (T2D) in Caucasian and Asian populations, little or none of such findings have been revealed in Nigeria. Hence, this study was aimed to assess the relationship between E23K polymorphic variant of the KCNJ11 gene and T2D in.. Read More»

Genet. Mol. Res. 17(1): gmr16039889

DOI: 10.4238/gmr16039889

Human Genetics   Research Article
The Disruption of Klf6-Related Super-Enhancer Induces Growth Inhibition and Apoptosis in Human HepG2 Cells

Authors: KumChol Ri, KumChol Kim, SunHyok Kong, JuHua Ri

Klf6 is a member of the Krüppel-like factor family, which is a group of zinc finger transcription factors involved in differentiation and development. In general, Klf6 gene plays an important role in growth-related signal transduction pathways, cell proliferation, apoptosis, and angiogenesis. Recently, the Klf6 gene is co.. Read More»

Genet. Mol. Res. 17(1): gmr16039888

DOI: 10.4238/gmr16039888

Plant Genetics   Research Article
Estimate of natural cross-pollination rate of Capsicum annuum using a codominant molecular marker associated with fruit pungency

Authors: EV Justino, MEN Fonseca, ME Ferreira, LS Boiteux, PP Silva, WM Nascimento

The production of seeds with high genetic quality requires accurate estimates of the natural cross-pollination rate in cultivated Capsicum species. This is important in order to establish the most suitable isolation distance among fields of distinct genotypes, to minimize the risk of genetic contamination and to ensure that th.. Read More»

Genet. Mol. Res. 17(1): gmr16039887

DOI: 10.4238/gmr16039887

Plant Genetics   Research Article
Marker-Assisted elimination of drought-susceptible accessions in upland rice breeding

Authors: Ariadna Faria Vieira, Gabriel Feresin Pantali�£o, Fernanda Martins Abreu, Ricardo Dias Silveira, Ana Letycia Basso Garcia, Leandro Gomide Neves, Rosana Pereira Vianello, Adriano Pereira Castro, Claudio Brondani

Breeding for water-deficit tolerance is fundamental to guarantee the sustainability of upland rice production, mainly due to the possibility of an increased frequency of drought episodes due to climate change. This work aimed to identify single nucleotide polymorphism (SNP) markers, derived from RNA sequencing (RNA-Seq), genom.. Read More»

Genet. Mol. Res. 17(1): gmr16039886

DOI: 10.4238/gmr16039886

Plant Genetics   Research Article
Lentinus crinitus strains respond differently to cultivation pH and temperature

Authors: R.A. Marim, K.V. Avelino, G.A. Linde, N.B. Colauto and J.S. Valle

Fungus ability to respond to environmental changes allows their adaptation to a wide variety of conditions such as pH, temperature, light, nutrient availability, chemicals, and competition among species. Temperature and pH can affect fungal growth as well as their metabolism. Knowing these factors on fungus species is relevant.. Read More»

Genet. Mol. Res. 17(1): gmr16039885

DOI: 10.4238/gmr16039885

Human Genetics   Research Article
Effect of food intake on biomarkers for cardiovascular disease and inflammation analyzed with the Proseek Multiplex CVD II kit

Authors: Magnus Dencker, Ylva G�¥rdinger, Ola Bj�¶rgell, Joanna Hlebowicz

Objectives: The present study evaluates the effect of food intake on 90 biomarkers for cardiovascular disease (CVD) and inflammation with the Proseek Multiplex CVD II kit. Methods: Twenty-two healthy subjects (11 male and 11 females aged 25.9±4.2 years) were investigated. A total of 90 biomarkers were measured before a .. Read More»

Genet. Mol. Res. 17(1): gmr16039884

DOI: 10.4238/gmr16039884