Table of Contents | Genet. Mol. Res.2016(1)
Differential expression of the lethal gene Luteus-Pa in cacao of the Parinari series
Authors: B.C. Rehem1, A.-A.F. Almeida1, G.S.F. Figueiredo1, A.S. Gesteira2, S.C. Santos1, R.X. Corr�?ªa1, M.M. Yamada3 and R.R. Valle3
The recessive lethal character Luteus-Pa is found in cacao (Theobroma cacao) genotypes of the Parinari series (Pa) and is characterized by expression of leaf chlorosis and seedling death. Several genotypes of the Pa series are bearers of the gene responsible for the expression of the Luteus-Pa character, which can be used as a tool for determining relatio.. Read More»
Genet. Mol. Res. 15(1): gmr.15014925
DOI: 10.4238/gmr.15014925
Silencing miR-181a produces neuroprotection against hippocampus neuron cell apoptosis post-status epilepticus in a rat model and in children with temporal lobe epilepsy
Authors: L. Ren1*, R. Zhu2* and X. Li1
Epilepsy is one of the most frequent neurological disorders. Recently, the regulation of microRNAs was found to be associated with epilepsy, but the molecular mechanism by which microRNA influences epilepsy process remains to be unveiled and the development of microRNA-based therapy requires more intensive research. In this study, five microRNAs with pote.. Read More»
Genet. Mol. Res. 15(1): gmr.15017798
DOI: 10.4238/gmr.15017798
Chloroplast analysis of Zelkova schneideriana (Ulmaceae): genetic diversity, population structure, and conservation implications
Authors: H.L. Liu1,2, R.Q. Zhang2, M.L. Geng3, J.Y. Zhu1, J.C. An1 and J.L. Ma1
elkova schneideriana is endemic to China and belongs to the Ulmaceae. It is listed as a Near Threatened species in the China Biodiversity Red Data Book. We conducted a phylogeographical study of two chloroplast regions (psbA-trnH and trnG-trnM) in several Chinese Z. schneideriana populations, in order to examine the genetic diversity, population structure.. Read More»
Genet. Mol. Res. 15(1): gmr.15017739
DOI: 10.4238/gmr.15017739
Relationship between TLR4 and CCL2 expression and recurrent spontaneous abortion
Authors: P. Li1,2, H.L. Wu2 and B.H. Dong1
The increasing incidence of recurrent spontaneous abortion (RSA) severely affects women’s health. The involvement of the immune system during pregnancy and its contribution to RSA draw researchers’ attention. Both Toll-like receptor 4 (TLR4) and chemokine (C-C motif) ligand 2 (CCL2) have been linked to various pregnancy disorders. In this stud.. Read More»
Genet. Mol. Res. 15(1): gmr.15016882
DOI: 10.4238/gmr.15016882
Role of interleukin-6 polymorphisms in the development of allergic rhinitis
Authors: N. Zhao1,2, H.J. Liu2, Y.Y. Sun3 and Y.Z. Li1
The aim of this study was to investigate the role played by the IL-6 rs1800795 (-174G/C) and rs1800796 (-572G>C) polymorphisms in the susceptibility to allergic rhinitis in a Chinese population. A total of 265 patients with allergic rhinitis and 265 controls from our hospital were enrolled in this study. The IL-6 rs1800795 and rs1800796 polymorphisms w.. Read More»
Genet. Mol. Res. 15(1): gmr.15016987
DOI: 10.4238/gmr.15016987
Production and genetic analysis of resynthesized Brassica napus from a B. rapa landrace from the Qinghai-Tibet Plateau and B. alboglabra
Authors: H.D. Liu*, Z.G. Zhao*, D.Z. Du, C.R. Deng and G. Fu
This study aimed to reveal the genetic and epigenetic variations involved in a resynthesized Brassica napus (AACC) generated from a hybridization between a B. rapa (AA) landrace and B. alboglabra (CC). Amplified fragment length polymorphism (AFLP), methylation-sensitive amplified polymorphism, and the cDNA-AFLP technique were performed to detect changes b.. Read More»
Genet. Mol. Res. 15(1): gmr.15017146
DOI: 10.4238/gmr.15017146
Temporal and spatial expression profiles of Frizzled 3 in the ovary during the estrous cycle
Authors: S.B. Wang1,2,3, Y.P. Liu1,2, Z.H. Zhang2, Z.K. Wang2,3, Y.X. Xu3 and Z.C. Wang1,2,3
Frizzled 3 is an important receptor in the Wnt/β-catenin pathway, a conserved signaling pathway that regulates gene expression and controls diverse developmental processes. However, the role of this protein during follicular development in the adult ovary is not known. The present study was designed to investigate the expression and localization of F.. Read More»
Genet. Mol. Res. 15(1): gmr.15017152
DOI: 10.4238/gmr.15017152
Biological analysis of chronic lymphocytic leukemia: integration of mRNA and microRNA expression profiles
Authors: L. Dong1, K.H. Bi1, N. Huang1 and C.Y. Chen2
Chronic lymphocytic leukemia (CLL) is a disease that involves progressive accumulation of nonfunctioning lymphocytes and has a low cure rate. There is an urgent requirement to determine the molecular mechanism underlying this disease in order to improve the early diagnosis and treatment of CLL. In this study, genes differentially expressed between CLL sam.. Read More»
Genet. Mol. Res. 15(1): gmr.15017170
DOI: 10.4238/gmr.15017170