M. Deng

Publications of : M. Deng

Human Genetics Research Article

MiR-200c inhibits metastasis of breast tumor via the downregulation of Foxf2

The forkhead box F2 (Foxf2) gene suppresses epithelial-mesenchymal transition via the modulation of transcription of zinc finger E-box-binding homeobox 1 (Zeb1) and epithelial (E)-cadherin, thereby inhibiting tumor metastasis. Additionally, the specific binding of microRNA (miR)-200c to Foxf2 mRNA impedes metastatic pulmonary cancer. However, the role of miR-200c in.. Read More»

Genet. Mol. Res. 16(3): gmr16038971

DOI: 10.4238/gmr16038971

Animal Genetics Research Article

Involvement of the mitfa gene in the development of pigment cell in Japanese ornamental (Koi) carp (Cyprinus carpio L.)

J.H. Liu, S. Wen, C. Luo, Y.Q. Zhang, M. Tao, D.W. Wang,S.M. Deng and Y.M. Xiao

A colored phenotype is an important feature of ornamental fish. In mammals, microphthalmia-associated transcription factor (MITF) was found to regulate the development of melanocytes. In this study, the mitfa cDNA was first cloned from the Japanese ornamental (Koi) carp (Cyprinus carpio L.), an important ornamental freshwater fish. The full-length cDNA of the mitfa gene contains 1634 bp, coding.. Read More»

Genet. Mol. Res. 14(1): http://dx.doi.org/2015.March.31.7

DOI: http://dx.doi.org/10.4238/2015.March.31.7

Human Genetics Research Article

miR-499A>G rs3746444 and miR-146aG>C expression and hepatocellular carcinoma risk in the Chinese population

Y.F. Shan1, Y.H. Huang1, Z.K. Chen1, K.T. Huang1, M.T. Zhou1, H.Q. Shi1, Q.T. Song1, Z.P. Yu1, A.M. Deng2 and Q.Y. Zhang1

We conducted a case-control study of a possible association of miR-499A>G rs3746444 and miR-146aG>C rs2910164 with risk of hepatocellular carcinoma. Samples from 172 hepatocellular carcinoma patients and 185 cancer-free controls were collected from October 2008 to December 2011. PCR-RFLP analysis was performed to determine the polymorphisms in each individual. The MAFs of miR-146aG>C a.. Read More»

Genet. Mol. Res. 12(4): 2013.November.7.11

DOI: 10.4238/2013.November.7.11

Plant Genetics Research Article

Polymorphisms of the cocaine-amphetamine-regulated transcript (CART) gene and their association with reproductive traits in Chinese goats

P.Q. Wang, L.M. Deng, B.Y. Zhang, M.X. Chu and J.Z. Hou

Polymorphisms of the CART gene were investigated by PCR-single-strand conformation polymorphism analysis in 540 samples from 10 goat breeds. Ten novel single-nucleotide polymorphisms as well as three microsatellites were detected; a mutation, 77T→C, led to an amino acid change (Leu→Ser). Associations between polymorphic loci and reproductive traits were an.. Read More»

Genet. Mol. Res. 10(2): vol10-2gmr1091

DOI: 10.4238/vol10-2gmr1091

Animal Genetics Research Article

Structural analysis of a 4414-bp element in Drosophila melanogaster

B. Yu, X.T. Wang, H.W. Li, C.J. Zhao, C.X. Wu and X.M. Deng

We cloned a 4414-bp element from a mutant of Drosophila melanogaster. Its insertion site was 18,929,626 bp. Analysis of the nucleotide and amino acid sequences demonstrated that the element is homologous to Pifo_I, first obtained from D. yabuka, which belongs to the gypsy/Ty3 subfamily. We also obtained a 3754-bp length element from a wild-type fly by PCR, with a pa.. Read More»

Genet. Mol. Res. 10(2): vol10-2gmr987

DOI: 10.4238/vol10-2gmr987

Plant Genetics Research Article

Fermentation of Foc TR4-infected bananas and Trichoderma spp

J. Yang, B. Li, S.W. Liu M.K. Biswas, S. Liu, Y.R. Wei, C.W. Zuo, G.M. Deng, R.B. Kuang, C.H. Hu, G.J. Yi and C.Y. Li

Fusarium wilt (also known as Panama disease) is one of the most destructive banana diseases, and greatly hampers the global production of bananas. Consequently, it has been very detrimental to the Chinese banana industry. An infected plant is one of the major causes of the spread of Fusarium wilt to nearby regions. It is essential to develop an efficient and environ.. Read More»

Genet. Mol. Res. 15(4): gmr15048494

DOI: 10.4238/gmr15048494