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L.X. Wang

Publications of : L.X. Wang
Animal Genetics   Research Article

mRNA and protein expression levels of four candidate genes for ear size in Erhualian and Large White pigs

Porcine ear size is an important characteristic for distinguishing among pig breeds. In a previous genome-wide association study of porcine ear size, LEM domain-containing 3 (LEMD3), methionine sulfoxide reductase B3 (MSRB3), high mobility group AT-hook 2 (HMGA2), and Wnt inhibitory factor 1 (WIF1) were implicated as important candidate genes for ear size. This stud.. Read More»

Genet. Mol. Res. 16(2): gmr16029252

DOI: 10.4238/gmr16029252

Animal Genetics   Research Article

Expression of OPG, RANKL, and RUNX2 in rabbit periodontium under orthodontic force

    B. Li, Y.H. Zhang, L.X. Wang, X. Li and X.D. Zhang

This study aims to investigate the expression changes of RANKL, RUNX2, and OPG in rabbit periodontal tissues under orthodontic force and explore its effect on the remodeling of periodontal tissues. A total of 16 specific pathogen-free rabbits were used in this study. The maxillary appliance was worn on the right (experimental) side, and the appliance-free left side was used as the control. Rabb.. Read More»

Genet. Mol. Res. 14(4): 2015.December.29.48

DOI: 10.4238/2015.December.29.48

Animal Genetics   Research Article

Identification of genes and pathways related to lipopolysaccharide signaling in duckling spleens

    B. Deng, T. Yu, W. Liu, S.Q. Ye, L.X. Wang, Y. Yang, P. Gong, Z.P. Ran, H.J. Huang and J.H. Wen

Lipopolysaccharide (LPS), the major component of the outer cell wall of Gram-negative bacteria, activates the immune system and threatens the health of livestock and poultry. However, little is known about the genes and pathways involved in the immune response of ducklings to LPS. To elucidate the genes involved in the response of 7-day-old duckling spleens treated with LPS, RNA from LPS-treate.. Read More»

Genet. Mol. Res. 14(4): 2015.December.16.32

DOI: 10.4238/2015.December.16.32

Plant Genetics   Research Article

Identification of quantitative trait loci for mineral elements in grains and grass powder of barley

    Y.W. Zeng, J. Du, X.M. Yang, X.Y. Pu, L.X. Wang, J.Z. Yang, L.J. Du, T. Yang, S.M. Yang and Z.H. Sun

Mineral elements in barley (Hordeum vulgare) play an important physiological role in global human health. In this study, quantitative trait loci (QTLs) for concentration of nine mineral elements in barley grain and grass powder were detected in a population of 193 recombinant inbred lines of the barley cross Ziguangmangluoerling x Schooner and the parents. We observ.. Read More»

Genet. Mol. Res. 15(4): gmr15049103

DOI: 10.4238/gmr15049103

Medical Genetics   Research Article

Porcine MAP3K5 analysis: molecular cloning, characterization, tissue expression pattern, and copy number variations associated with residual feed intake

    L. Pu, L.C. Zhang, J.S. Zhang, X. Song, L.G. Wang, J. Liang, Y.B. Zhang, X. Liu, H. Yan, T. Zhang, J.W. Yue, N. Li, Q.Q. Wu and L.X. Wang

Mitogen-activated protein kinase kinase kinase 5 (MAP3K5) is essential for apoptosis, proliferation, differentiation, and immune responses, and is a candidate marker for residual feed intake (RFI) in pig. We cloned the full-length cDNA sequence of porcine MAP3K5 by rapid-amplification of cDNA ends. The 5451-bp gene contains a 5'-untranslated region (UTR) (718 bp), a coding region (3738 bp), and.. Read More»

Genet. Mol. Res. 15(3): gmr.15037998

DOI: 10.4238/gmr.15037998

Animal Genetics   Research Article

Observed impacts of insulin therapy on callus cell transforming growth factor-beta 1 expression in diabetic rats

    L.X. Wang, H.L. Jiang and S.L. Du

The expression of transforming growth factor-beta 1 (TGF-β1) inside the callus cells of diabetic rats and the impact of insulin therapy on its expression and biomechanics was investigated. The rats were randomly divided as follows: an insulin therapy group (IT), a diabetic model group (DM), and a non-diabetic control group (NC). Bone specimens from each group were extracted at different ti.. Read More»

Genet. Mol. Res. 14(2): 2015.May.12.10

DOI: 10.4238/2015.May.12.10

Human Genetics   Research Article

Molecular cloning, tissue expression pattern, and copy number variation of porcine SCUBE3

    X. Liu*, L.G. Wang*, L.C. Zhang, H. Yan, K.B. Zhao, J. Liang, N. Li, L. Pu,T. Zhang and L.X. Wang

The signal peptide CUB EGF-like domain-containing protein 3 (SCUBE3) gene is a member of SCUBE gene family and plays important roles in bone cell biology and the determination of limb bone length. In this study, the full-length transcript of porcine SCUBE3 was cloned using reverse transcription-polymerase chain reaction and rapid amplification of cDNA ends. The full-length sequence of porcine S.. Read More»

Genet. Mol. Res. 15(1): gmr.15017010

DOI: 10.4238/gmr.15017010

Human Genetics   Research Article

In vitro inhibition of invasion and metastasis in colon cancer cells by TanIIA

    R.W. Zhang, Z.G. Liu, Y. Xie, L.X. Wang, M.C. Li and X. Sun

The purpose of this study was to investigate the effect of the traditional Chinese medicine TanIIA on the viability, invasion, and metastasis of SW480 cells. SW480 cells were treated with TanIIA for 24 h, and MTT assays were performed to determine the effect of TanIIA on cell viability. Transwell transmembrane experiments were applied to test the effect of 1.0 mg/mL TanIIA on SW480 cell invasio.. Read More»

Genet. Mol. Res. 15(3): gmr.15039008

DOI: 10.4238/gmr.15039008

Microbial Genetics   Research Article

Molecular analysis and frequency of Staphylococcus aureus virulence genes isolated from bloodstream infections in a teaching hospital in Tianjin, China

    L.X. Wang Z.D. Hu Y.M. Hu B. Tian Jing Li F.X. Wang H. Yang H.R. Xu Y.C. Li J. Li

Staphylococcus aureus is an important cause of bloodstream infections worldwide. We examined the prevalence of genes that encode erythromycin ribosome methylase and bacterial toxins in S. aureus collected from bloodstream infections. Sixty different S. aureus isolates were obtained from blood cultures of patients who were admitted to a Teaching Hospital in Tianjin from January 2006 to August 20.. Read More»

Genet. Mol. Res. 12(1): 2013.March.11.12

DOI: 10.4238/2013.March.11.12

Human Genetics   Research Article

Effects of atorvastatin in combination with ezetimibe on carotid atherosclerosis in elderly patients with hypercholesterolemia

    P. Luo, L. Li, L.X. Wang, H.H. Zhu, S. Du, S.L. Wu, Y.G. Han and G.G. Wang

The aim of this study was to observe the effects of atorvastatin combined with ezetimibe on carotid atherosclerosis in elderly patients with hypercholesterolemia. A total of 84 elderly hypercholesterolemic patients complicated with carotid atherosclerosis were divided into control group (atorvastatin alone) and combined group (atorvastatin combined with ezetimibe) a.. Read More»

Genet. Mol. Res. 13(2): 2014.April.3.10

DOI: 10.4238/2014.April.3.10