J. Peng
Molecular identification of variety purity in a cotton hybrid with unknown parentage using DNA-SSR markers
Molecular identification of hybrid purity is difficult in regional trials of cotton varieties and hybrid trials. In particular, the molecular detection of hybrid purity has not yet been reported in the case of unknown parentage. In this study, we screened 5000 pairs of primers and chose 17 pairs of core simple sequence repeat (SSR) primers to determine the F1 purity.. Read More»
Genet. Mol. Res. 16(3): gmr16039799
DOI: 10.4238/gmr16039799
A de novo 2q35-q36.1 deletion incorporating IHH in a Chinese boy (47,XYY) with syndactyly, type III Waardenburg syndrome, and congenital heart disease
Reports of terminal and interstitial deletions of the long arm of chromosome 2 are rare in the literature. Here, we present a case report concerning a Chinese boy with a 47,XYY karyotype and a de novo deletion comprising approximately 5 Mb between 2q35 and q36.1, along with syndactyly, type III Waardenburg syndrome, and congenital heart disease. High-resolution chro.. Read More»
Genet. Mol. Res. 15(4): gmr15049060
DOI: 10.4238/gmr15049060
Genetic variations in microRNA genes and susceptibility to hepatocellular carcinoma
We conducted a hospital-based case-control study to investigate the effect of the miR-146aG>C and miR-499A>G polymorphisms on the risk of hepatocellular carcinoma (HCC) in a Chinese population. This study was 1:1 matched case-control study consisting of 184 HCC patients and 184 control subjects. miR-146aG>C and miR-499A>G polymorphisms were genotyped by polymerase chain reaction-res.. Read More»
Genet. Mol. Res. 14(1): 2015.March.20.2
DOI: 10.4238/2015.March.20.2
Expression of prion protein in the cerebrospinal fluid of patients with Parkinson’s disease complicated with rapid eye movement sleep behavior disorder
Parkinson’s disease (PD) is one of the most common neurodegenerative diseases and mainly manifests with decreasing numbers of dopaminergic neurons. Rapid eye movement (REM) sleep behavior disorder (RBD) has an incidence of 15-47% in all PD patients. Prion proteins (PrPs), which are expressed in both neurons and glial cells of the brain, are believed to be corr.. Read More»
Genet. Mol. Res. 16(1): gmr16019022
DOI: 10.4238/gmr16019022
Molecular cloning and expression analysis of the GNAS gene in pig and porcine fibroblast cells
The Alpha subunit of the stimulatory guanine nucleotide-binding protein (GNAS) is a complex imprinted gene. The major product of the GNAS gene is the α-subunit of the guanine nucleotide-binding protein (Gas), which plays a key role in multiple signal transduction pathways. Gas is required for the production of the receptor-stimulated intracellular cyclic adeno.. Read More»
Genet. Mol. Res. 13(3): 2014.July.24.26
DOI: 10.4238/2014.July.24.26
Association of LRP5 Ala1330Val polymorphism with fracture risk: a meta-analysis
Numerous studies have evaluated the association between the Ala1330Val polymorphism of the low-density lipoprotein receptor-related proteins 5 (LRP5) gene and fracture risk. However, the specific association is still controversial. The aim of this study was to investigate their correlation via meta-analysis. and EMBASE databases were searched, and data were extracted independently by two review.. Read More»
Genet. Mol. Res. 15(1): gmr.15017552
DOI: 10.4238/gmr.15017552
Isolation, identification, and degradation performance of a PFOA-degrading strain
The perfluorooctanoic acid (PFOA)-degrading strain YAB1 was isolated from the soil near a perfluorinated compound production plant through acclimation and enrichment culture, using PFOA as the sole carbon source. This strain was preliminarily identified as Pseudomonas parafulva based on colony morphology, physiological and biochemical features, and 16S rRNA gene seq.. Read More»
Genet. Mol. Res. 15(2): gmr.15028043
DOI: 10.4238/gmr.15028043
Investigation into withdrawal of entecavir after 20 months in an HBsAb-positive patient who received HBsAg allogeneic stem cell transplantation
Hepatitis B virus (HBV) infection of donors and recipients is not an absolute contraindication for allogeneic stem cell transplantation (allo-HSCT). We studied a patient who received allo-HSCT from an HBsAg-positive donor. The patient was administered long-term immunosuppressive therapy and treated with the oral anti-viral medication, entecavir (ETV). During this treatment, there was no hepatit.. Read More»
Genet. Mol. Res. 14(4): 2015.December.22.22
DOI: 10.4238/2015.December.22.22
Mitochondria-dependent apoptogenic activity of the aqueous root extract of Croton membranaceus against human BPH-1 cells
The results of previous case-control studies examining the relationship between the interleukin (IL)-6 gene -174G>C polymorphism and lung cancer are controversial. In this study, we evaluated the relationship between the IL-6 gene -174G>C polymorphism and lung cancer. We selected 5 case-control studies related to the IL-6 gene -174G>C polymorphism and lung cancer by searching the PubMe.. Read More»
Genet. Mol. Res. 14(1): 2015.January.15.18
DOI: 10.4238/2015.January.15.18
In vitro effects and mechanisms of lycopene in MCF-7 human breast cancer cells
Breast cancer adversely affects the health status of women; therefore, the prevention and treatment of breast cancer is of critical importance. Lycopene is known to possess several biological effects such as removal of free radicals, alleviation of biological oxidative injury, and inhibition of tumor growth. In this study, we aimed to illustrate the effect of lycope.. Read More»
Genet. Mol. Res. 16(2): gmr16029434
DOI: 10.4238/gmr16029434
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