Human Genetics
GSTM1 polymorphism in patients with clinical manifestations of atherosclerosis
Authors: D.A. Rodrigues, J.V.M. Martins, K.S.F. e Silva, I.R. Costa, M.H. Lagares, F.L. Campedelli, A.M. Barbosa, M.P. de Morais and K.K.V.O. Moura
Atherosclerosis is characterized by lesions, called atheroma or atheromatous plaques, in the inner layer of blood vessels, which block the vascular lumen and weaken the underlying tunica media. Several modifiable and non-modifiable risk factors for the development of atherosclerosis exist. The modifiable risk factors include h.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019101
- DOI:
- 10.4238/gmr16019101
RAPD analysis of genetic diversity and population structure of Elymus sibiricus (Poaceae) native to the southeastern Qinghai-Tibet Plateau, China
Authors: X. Ma S.-Y. Chen S.-Q. Bai X.-Q. Zhang D.-X. Li C.-B. Zhang J.-J. Yan
Genetic diversity of Elymus sibiricus (Poaceae) was examined in eight populations from the southeast Qinghai-Tibet Plateau. We detected 291 RAPD polymorphic loci in 93 samples. The percentage of polymorphic bands (PPB) was 79%. Genetic diversity (HE) was 0.264, effective number of alleles (NE) was 1.444, Shannon’s information index (HO) was 0.398, a.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.June.27.5
- DOI:
- 10.4238/2012.June.27.5
Red Sindhi cattle in Brazil: population structure and distribution
Authors: J.C.C. Panetto, M.V.G.B. Silva, R.M.H. Leite, M.A. Machado,F.A.T. Bruneli, D.R.L. Reis, M.G.C.D. Peixoto, R.S. Verneque
The Red Sindhi cattle breed was imported to Brazil in small numbers. Nowadays, the herds of this breed are distributed in the Northeast, Southeast and Midwest regions of the country. In this study, DNA samples of animals originating from 15 herds in the Northeast and Southeast regions have been analyzed to obtain the ancestry .. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019501
- DOI:
- 10.4238/gmr16019501
Integrated statistical learning of metabolic ion mobility spectrometry profiles for pulmonary disease identification
Authors: A.-C. Hauschild J.I. Baumbach J. Baumbach
Exhaled air carries information on human health status. Ion mobility spectrometers combined with a multi-capillary column (MCC/IMS) is a well-known technology for detecting volatile organic compounds (VOCs) within human breath. This technique is relatively inexpensive, robust and easy to use in every day practice. However, the potential of this methodolog.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.July.10.17
- DOI:
- 10.4238/2012.July.10.17
A clinical study of bone mesenchymal stem cells for the treatment of hepatic fibrosis induced by hepatolenticular degeneration
Authors: D. Zhang
The efficacy of bone marrow mesenchymal stem cell (BMSC) on liver fibrosis in animal has been proven, but a few studies have been made in human body and few such researches in China. This study was designed to investigate the effect of BMSC treatment on hepatic fibrosis induced by hepatolenticular degeneration and the influenc.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019352
- DOI:
- 10.4238/gmr16019352
Interactions among methylenetetrahydrofolate reductase (MTHFR) and cystathionine �²-synthase (CBS) polymorphisms - a cross-sectional study: multiple heterozygosis as a risk factor for higher homocysteine levels and vaso-occlusive episodes
Authors: F.M. Amaral, A.L. Miranda-Vilela, G.S. Lordelo, I.F. Ribeiro, M.B. Daldegan and C.K. Grisolia
High plasma homocysteine (Hcy) âÂ?Â?âÂ?Â?levels may be responsible for vaso-occlusive episodes and may have acquired and/or genetic causes. This cross-sectional study aimed to investigate the role of methylenetetrahydrofolate reductase (MTHFR; C677T; A1298C) and cystathionine-β-synthase (CBS; T833C/844ins68, G919A) poly.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019374
- DOI:
- 10.4238/gmr16019374
Inhibition of miR-660-5p expression suppresses tumor development and metastasis in human breast cancer
Authors: Y. Shen, Y.F. Ye, L.W. Ruan, L. Bao, M.W. Wu and Y. Zhou
Breast cancer, which derives from the epithelium of the mammary glands, is one of the most common cancers diagnosed in women globally. To date, the authors of many studies have reported that the deregulation of microRNAs (miRNAs) plays a crucial role in the occurrence, development, and metastasis of tumors. Here, we discovered.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019479
- DOI:
- 10.4238/gmr16019479
Spermatogenesis and nucleolar behavior in males of aquatic Heteroptera
Authors: M.M.U. Castanhole
Aspects of spermatogenesis and nucleolar behavior were analyzed in Brachymetra albinerva, Cylindrostethus palmaris, Halobatopsis platensis, Limnogonus aduncus (Gerridae), Martarega sp (Notonectidae), Rhagovelia whitei, and Rhagovelia sp (Veliidae). The testicles are rounded (Veliidae), elongated (Gerridae) or spiral (Notonectidae) and have a transparent m.. Read More»
- Genet. Mol. Res. 8(3):
- vol8-3ta019
- DOI:
- 10.4238/vol8-3ta019
MNS, Duffy, and Kell blood groups among the Uygur population of Xinjiang, China
Authors: G.Y. Lin, X.L. Du, J.J. Shan, Y.N. Zhang Y.Q. Zhang, Q.H. Wang
Human blood groups are a significant resource for patients, leading to a fierce international competition in the screening of rare blood groups. Some rare blood group screening programs have been implemented in western countries and Japan, but not particularly in China. Recently, the genetic background of ABO and Rh blood grou.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019176
- DOI:
- 10.4238/gmr16019176
Identification of ANAPC13 gene polymorphisms associated with body measurement traits in Bos taurus
Authors: B.J. Jiang X.L. Zhan C.Z. Fu H.B. Wang G. Cheng L.S. Zan
Body measurement traits, influenced by genes and environmental factors, play numerous important roles in the value assessment of productivity and economy. There has been some indication that ANAPC13 influences adult height. We used PCR-SSCP and DNA sequencing technology to identify polymorphisms in the ANAPC13 gene. A polymorphism in intron 1 (A > G at.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.June.15.6
- DOI:
- 10.4238/2012.June.15.6