Cytogenomics
ZNF797 plays an oncogenic role in gastric cancer
Authors: D. Momenzadeh1, S. Rahman Zadeh1, M. Rezaei-Tavirani1, A. Baradaran-Rafii2, F. Ghasemvand1 and S. Heidari-Keshel1
Human cancer cells resemble stem cells in expression signatures leading them to share some features, most notably, selfrenewal. A complex network of transcription factors and signaling molecules are required for continuation of this trait. ZNF797 (SALL4) is a zinc finger transcriptional activator crucial for maintenance of self-renewal in stem cells; howe.. Read More»
- Genet. Mol. Res. 13(4):
- 2014.October.20.18
- DOI:
- 10.4238/2014.October.20.18
Characterization of allele-specific expression of the X-linked gene MAO-A in trophectoderm cells of bovine embryos produced by somatic cell nuclear transfer
Authors: A.R. Ferreira, L.F.C. Aguiar Filho, R.V. Sousa, R. Sartori and M.M. Franco
Somatic cell nuclear transfer (SCNT) may affect epigenetic mechanisms and alter the expression of genes related to embryo development and X chromosome inactivation (XCI). We characterized allele-specific expression of the X-linked gene monoamine oxidase type A (MAO-A) in the trophectoderm (TF) of embryos produced by SCNT. Tota.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.5.26
- DOI:
- 10.4238/2015.October.5.26
Association of A-20C polymorphism in the angiotensinogen gene with essential hypertension: a meta-analysis
Authors: R. Zeng, Q.P. Wang, M.X. Fang, J. Zhuang and R.X. Fan
The A-20C polymorphism in the angiotensinogen (AGT) gene has been associated with increased risk of essential hypertension in several studies; however, these studies gave inconsistent results. In this study, we performed a meta-analysis to assess the association between AGT A-20C polymorphism and essential hypertension. Published literature was retrieved .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.21.19
- DOI:
- 10.4238/2015.October.21.19
Characterization and expression analysis of somatic embryogenesis receptor-like kinase genes from Phalaenopsis.
Authors: Y.W. Huang, Y.J. Tsai and F.C. Chen
Somatic embryogenesis receptor-like kinase (SERK) genes have been found to be involved in the somatic embryogenesis of several plant species. We identified and characterized 5 PhSERK genes in the Phalaenopsis orchid. The amino acid sequences of PhSERKs and other SERK proteins are highly conserved, with the highest homology obs.. Read More»
- Genet. Mol. Res. 13(4):
- 2014.December.18.11
- DOI:
- 10.4238/2014.December.18.11
Physical mapping of the Period gene on meiotic chromosomes of South American grasshoppers (Acridomorpha, Orthoptera)
Authors: T.E. Souza1,2, D.L. Oliveira1, J.F. Santos1 and T.T. Rieger1,2
The single-copy gene Period was located in five grasshopper species belonging to the Acridomorpha group through permanent in situ hybridization (PISH). The mapping revealed one copy of this gene in the L1 chromosome pair in Ommexecha virens, Xyleus discoideus angulatus, Tropidacris collaris, Schistocerca pallens, and Stiphra robusta. A possible second cop.. Read More»
- Genet. Mol. Res. 13(4):
- 2014.December.19.4
- DOI:
- 10.4238/2014.December.19.4
New microsatellite markers for the abalone Haliotis midae developed by 454 pyrosequencing and in silico analyses
Authors: R. Slabbert J.-A. Hepple C. Rhode A.E. Bester-Van der Merwe R. Roodt-Wilding
Farming of Haliotis midae is the most lucrative aquaculture venture in South Africa. The genome of this species needs to be studied to assist in selective breeding programs aimed at increasing overall yield, and molecular markers will be required to attain this goal. We identified and characterized 82 polymorphic microsatellite loci by using repeat-enrich.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.August.24.2
- DOI:
- 10.4238/2012.August.24.2
A method for extracting period~10 modulations from DNA sequence correlations applied to the Drosophila melanogaster genome
Authors: J.C.O. Guerra P. Licinio
Nucleosome DNA packaging and positioning within the Drosophila melanogaster genome imposes a weak modulation, with a period of about 10 bp in the genomic composition correlations. We present formalism for extracting such modulations from an irreducible set of six correlation functions calculated along the D. melanogaster genome. These modulations were see.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.August.24.8
- DOI:
- 10.4238/2012.August.24.8
Stability and adaptability of popcorn genotypes in the State of Rio de Janeiro, Brazil
Authors: G.F. Pena A.T. do Amaral J�ºnior L.S.A. Gon�§alves L.S. Candido C. Vittorazzi R.M. Ribeiro S.P. Freitas J�ºnior
This study aimed to obtain estimates of stability and adaptability of phase launched materials and materials recommended in the country, for the northern and northwestern regions of Rio de Janeiro State, Brazil, and made a comparative analysis of different methods to evaluate stability and adaptability of grain yield and popping expansion. To this end, 10 ge.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.August.31.1
- DOI:
- 10.4238/2012.August.31.1
Construction of the intermediate vector pVBG2307 by incorporating vital elements of expression vectors pBI121 and pBI221
Authors: S.S. Ahmed Z.-H. Gong J.-J. Ji Y.-X. Yin H.-J. Xiao M.A. Khan A. Rehman I. Ahmad
Molecular chaperones of plasmid pBI121 carrying CaMV35S promoter and a nucleotide sequence of plasmid pBI221 were inserted into plasmid pCAMBIA2300 to construct an intermediate vector: pVBG2307. This novel vector pVBG2307 contains a greatly expanded multiple cloning site with an adjacent imported CaMV35S promoter sequence. This vector allows controlled tr.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.August.31.7
- DOI:
- 10.4238/2012.August.31.7
Recombinant adeno-associated virus BMP-4/7 fusion gene confers ossification activity in rabbit bone marrow stromal cells
Authors: S.H. Yuan C.B. Gao C.U. Yin Z.G. Yin
The biological effects of transfection of an adeno-associated virus (AAV) vector with bone morphogenetic proteins 4 and 7 (BMP-4/7) fusion gene (AAV-BMP-4/7) were determined in rabbit bone marrow stromal cells (BMSCs). BMP-4 and BMP-7 genes were obtained through one-step reverse transcriptase polymerase chain reaction from human placental cells. The BMP-4.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.August.31.8
- DOI:
- 10.4238/2012.August.31.8