Animal Genetics
Localization and expression of histone H2A variants during mouse oogenesis and preimplantation embryo development
Authors: B.J. Wu, F.L. Dong, X.S. Ma, X.G. Wang, F. Lin and H.L. Liu
Epigenetic modifications of the genome, such as histone H2A variants, ensure appropriate gene activation or silencing during oogenesis and preimplantation embryo development. We examined global localization and expression of the histone H2A variants, including H2A.Bbd, H2A.Z and H2A.X, during mouse oogenesis and preimplantatio.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.August.7.8
- DOI:
- 10.4238/2014.August.7.8
Molecular cloning and tissue distribution profiles of the chicken R-spondin1 gene
Authors: Y.Q. Han, J. Geng, H.T. Shi, X.M. Zhang, L.L. Du, F.T. Liu, M.M. Li, X.T. Wang, Y.Y. Wang and G.Y. Yang
Rspo1 belongs to the Rspo family, which is composed of 4 members (Rspo1-4) that share 40 to 60% sequence homology and similar domain organizations, and regulate the WNT signaling pathway via a common mechanism. Rspo1 plays a key role in vertebrate development and is an effective mitogenic factor of gastrointestinal epithelial cells. We report the cloning .. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.10.19
- DOI:
- http://dx.doi.org/10.4238/2015.April.10.19
Expression patterns and promoter activity analysis of UGP2 in pigs.
Authors: J.Y. Yu, S.M. Shao, K. Chen, M.G. Lei, and Y.Z. Xiong,
The function of the UDP-glucose pyrophosphorylase 2 gene (UGP2) in pig is not clear. In the present study, we used RNA isolated from Large White pigs and Chinese indigenous MeiShan pigs to examine the temporal coordination of changes in gene expression within muscle tissues. We cloned both the complete genomic DNA sequence and.. Read More»
- Genet. Mol. Res. 13(1):
- http://dx.doi.org/2014.February.28.8
- DOI:
- http://dx.doi.org/10.4238/2014.February.28.8
Effect of Jianpi Bushen prescription on the expression of SHP-1 and apoptosis-related genes in chemically damaged model mice
Authors: D.C. He, J.J. Xiao*, Y. Zhang, H. Lin, X.J. Ding and Y. Tu
We investigated the effect of Jianpi Bushen prescription (JBP) on the expression of the SHP-1 and apoptosis-related genes in chemically damaged model mice and a compound e-jiao slurry (EJS) group (positive control). Kunming mice received an abdominal injection of 100 mg/kg cyclophosphamide once a day for 3 consecutive days to .. Read More»
- Genet. Mol. Res. 13(3):
- 2014.August.7.11
- DOI:
- 10.4238/2014.August.7.11
Apoptosis, proliferation, and morphology during vein graft remodeling in rabbits
Authors: L. Wan, S.H. Dai, S.Q. Lai, L.Q. Liu, Q. Wang, H. Xu, W.J. Wang and J.C. Liu
Neo-intima development and atherosclerosis limit the long-term use of vein grafts for revascularization of ischemic tissues. Recently, studies have confirmed that proliferating cell nuclear antigen (PCNA) plays an important role in cell proliferation. Our research confirmed that 28 days after vein transplantation, PCNA express.. Read More»
- Genet. Mol. Res. 15(4):
- gmr.15048701
- DOI:
- 10.4238/gmr.15048701
Genetic diversity and population structure in Harpadon nehereus based on sequence-related amplified polymorphism markers
Authors: Z.H. Zhu, H.Y. Li*, Y. Qin and R.X. Wang
In this study, the genetic diversity among ten populations of the Bombay duck was studied on the basis of sequence-related amplified polymorphism (SRAP). The ten populations were collected from the East China Sea and South China Sea areas. A total of 98 loci were obtained from 292 individuals using eight SRAP primers. The aver.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.August.7.13
- DOI:
- 10.4238/2014.August.7.13
Polyploidy and epigenetic events in the evolution of Anura
Authors: M.L. Be�§ak
This article reviews the polyploidy events that have long been demonstrated to play a role in the evolution of Anura, while also discussing the importance of epigenetic control of gene expression and diversity. Findings on Brazilian autopolyploid anurans, mainly of the genus Odontophrynus, obtained in previous studies.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.August.7.15
- DOI:
- 10.4238/2014.August.7.15
Characterization of variation in the canine suppressor of cytokine signaling-2 (SOCS2) gene
Authors: Rincon G, Young AE, Bannasch DL and Medrano JF
Suppressor of cytokine signaling 2 (SOCS2) is a negative regulator of growth hormone signaling. The deletion of SOCS2 in mice results in a 30-50% increase in post-natal growth. In an effort to identify polymorphisms in the SOCS2 gene that may be associated with body size in dogs, we characterized the canine SOCS2 gene and anal.. Read More»
- Genet. Mol. Res. 6(1):
Molecular study of Astyanax altiparanae (Osteichthyes, Characidae) as a probable species complex
Authors: I.C. Depr�¡, V.N. Gomes, G.C. Depr�¡, I.J. Oliveira, S.M.A.P. Prioli and A.J. Prioli
Astyanax altiparanae, belonging to the bimaculatus group, which includes species with similar colors and morphology, occurs in the upper Paraná River basin. As the use of mitochondrial DNA has made great strides in the diagnosis of species, in previous researches, two strains were detected in A. altiparanae.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.August.7.16
- DOI:
- 10.4238/2014.August.7.16
Effect of lentivirus-mediated RNA interference of APC-Cdh1 expression on spinal cord injury in rats..
Authors: Y.-H. Qi, W.-L. Yao, C.-H. Zhang and Y.-Q. Guo
This study investigated cadherin-1 (Cdh1) expression in the sensorimotor cortex of rats after spinal cord injury (SCI). The repairing effect of Cdh1 was evaluated by silencing its expression with lentivirus-mediated RNAi. Twenty male Sprague-Dawley (SD) rats were randomly divided into a normal group and an operation group. Rat.. Read More»
- Genet. Mol. Res. 13(1):
- http://dx.doi.org/2014.February.28.9
- DOI:
- http://dx.doi.org/10.4238/2014.February.28.9