Animal Genetics
Development and characterization of microsatellite markers for Solen grandis using Illumina sequencing approach
Authors: Y.W. Feng, H.L. Jiang, Y.T. Liu, X.P. Wu, X.Q. Liu and X.M. Wei
Solen grandis is an important economic and overexploited bivalve species. In order to perform its fine-scale genetic analyses, 105 pairs of microsatellites with polymorphism were identified through Illumina Hiseq platform and bioinformatic assembly technology in this study. The estimated fragment size ranged from 100 to 268 bp.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019621
- DOI:
- 10.4238/gmr16019621
Genetic diversity and differentiation in natural populations of Arapaima gigas from lower Amazon revealed by microsatellites
Authors: P.F. Fazzi-Gomes, N. Melo, G. Palheta, S. Guerreiro, M. Amador, A.K. Ribeiro-dos-Santos, S. Santos and I. Hamoy
Genetic variability is one of the important criteria for species conservation decisions. This study aimed to analyze the genetic diversity and the population differentiation of two natural populations of Arapaima gigas, a species with a long history of being commercially exploited. We collected 87 samples of A. gigas from Gran.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019552
- DOI:
- 10.4238/gmr16019552
Protective effect of p38 MAPK inhibitor on wear debris-induced inflammatory osteolysis through downregulating RANK/RANKL in a mouse model
Authors: D. Chen, Y. Li, F. Guo, Z. Lu, C. Hei, P. Li and Q. Jin
Adult stem cells are known for their plasticity and their potential to differentiate into several different cell types; these characteristics have implications for cell therapy and reproductive biotechnologies. In this study, we report on the isolation and characterization of mesenchymal stem cells (MSC) derived from bovine and buffalo adipose tissue. Cel.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.January.15.6
- DOI:
- 10.4238/2015.January.15.6
Generation of bovine (Bos indicus) and buffalo (Bubalus bubalis) adipose tissue derived stem cells: isolation, characterization, and multipotentiality
Authors: R.V. Sampaio, M.R. Chiaratti, D.C.N. Santos, F.F. Bressan, J.R. Sangalli, A.L.A. S�¡, T.V.G. Silva, N.N. Costa, M.S. Cordeiro, S.S.D. Santos, C.E. Ambrosio, P.R. Adona, F.V. Meirelles, M.S. Miranda and O.M. Ohashi
Previous studies have indicated that the protein tyrosine phosphatase nonreceptor type 22 gene (PTPN22) is associated with type 1 diabetes (T1DM) in the Caucasian population. In the present study, we investigated the relationship between PTPN22 genetic polymorphisms and T1DM in Chinese children. A total of 202 children and adolescents with T1DM and 240 he.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.January.15.7
- DOI:
- 10.4238/2015.January.15.7
Identification and association of polymorphisms in CAPN1 and CAPN3 candidate genes related to performance and meat quality traits in chickens
Authors: A.M. FelÃ?Âcio C. Boschiero J.C.C. Balieiro M.C. Ledur J.B.S. Ferraz T. Michelan Filho A.S.A.M.T. Moura L.L. Coutinho
Meat quality is an important feature for the poultry industry and is associated with consumer satisfaction. The calpain 1 (CAPN1) gene is related to the tenderness process of meat post- mortem, and the calpain 3 (CAPN3) gene plays an important role in myofibrillar organization and growth. The objective of the present study was to identify polymorphisms in.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.February.8.12
- DOI:
- 10.4238/2013.February.8.12
Effects of feeding conditions on gene expression in chicken breast muscle
Authors: G.L. Gao, C. Wang, X.Z. Zhao, H.W. Wang, Q. Li, J. Li, K.S. Zhang, H. Zhong and Q.G. Wang
Chicken meat quality is becoming increasingly important among breeders and consumers. To understand the effect of feeding conditions on chicken meat quality, we investigated the profiles of genes expressed in chicken breast muscle. Using RNA sequencing, we identified 336, 321, and 387 differentially expressed genes among Cheng.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019119
- DOI:
- 10.4238/gmr16019119
Identification of polymorphisms and transcriptional activity of the proto-oncogene KIT located on both autosomal and B chromosomes of the Chinese raccoon dog
Authors: Y.M. Li1, Y. Zhang1, W.J. Zhu1, S.Q. Yan1 and J.H. Sun2
B chromosomes are dispensable and co-exist with autosomal and sex chromosomes. The karyotype of the Chinese raccoon dog (Nyctereutes procyonoides procyonoides) comprises 0-4 B chromosomes. The proto-oncogene KIT is found on all B chromosomes of the Chinese raccoon dog. In the present study, partial DNA and mRNA sequences of KIT were amplified and sequence.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017398
- DOI:
- 10.4238/gmr.15017398
Evaluation of the mutagenicity and antimutagenicity of soy phytoestrogens using micronucleus and comet assays of the peripheral blood of mice
Authors: A.M. Niwa R.J. Oliveira M.S. Mantovani
Studies show that soy imparts many favorable properties in the human body, including the prevention of chronic diseases such as osteoporosis, heart disease, cancer, and diabetes. Soy is rich in isoflavones, and it is a candidate for the chemoprevention of diseases owing to its low toxicity. In this study, a soy phytoestrogen (with high levels of the isoflavo.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.February.27.1
- DOI:
- 10.4238/2013.February.27.1
A genome-wide association study of growth trait-related single nucleotide polymorphisms in Chinese Yancheng chickens
Authors: C.F. Jin, Y.J. Chen, Z.Q. Yang, K. Shi, C.K. Chen
Chicken (Gallus gallus) growth traits are important economic traits, and many studies have been conducted on genetic selection for body weight. However, most of these studies have detected functional chromosome mutations or regions by conventional molecular markers or gene chips. In this study, we performed a new genome-wide a.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.1.30
- DOI:
- 10.4238/2015.December.1.30
Analysis of the mitochondrial COI gene and its informative potential for evolutionary inferences in the families Coreidae and Pentatomidae (Heteroptera)
Authors: H.V. Souza1, S.R.C. Marchesin2 and M.M. Itoyama1
The mitochondrial cytochrome oxidase subunit 1 (COI) gene is one of the most popular markers used for molecular systematics. Fragments of this gene are often used to infer phylogenies, particularly the region near the 5'-end, which is used by the DNA Barcoding Consortium. With a growing number of sequences being deposited in the DNA barcoding database, th.. Read More»
- Genet. Mol. Res. 15(1):
- 0.4238/gmr.15017428
- DOI:
- 0.4238/gmr.15017428