Animal Genetics
Expression of MMP-1, -2, and -8 in longissimus dorsi muscle and their relationship with meat quality traits in cattle
Authors: Y.X. Qi, X.H. Zhang, Y.Q. Wang, Y.Z. Pang, Z.B. Zhang, T.L. Zhang andZ.X. Zhang
The extracellular matrix (ECM) is the major macromolecule in skeletal muscle, which affects meat quality greatly. The remodeling of the ECM is mainly regulated by matrix metalloproteinases (MMPs). The expression patterns of MMP-1, -2, and -8 in longissimus dorsi muscle were explored using quantitative real-time polymerase chain reaction. The results show .. Read More»
- Genet. Mol. Res. 14(1):
- gmr.15017593
- DOI:
- 10.4238/gmr.15017593
Differential expression of FUT1 and FUT2 in Large White, Meishan, and Sutai porcine breeds
Authors: R.W. Xia1, W.Y. Qin1, L.N. Gan1, J. Wang1, S.L. Wu1,2 and W.B. Bao1,2
To assess the relationship between the expression of a(1,2)-fucosyltransferase (FUT1 and FUT2) genes and resistance to Escherichia coli F18 in weaned pigs, FUT1 and FUT2 expression levels in Large White, Meishan, and Sutai pigs (with resistance to E. coli F18) were determined using real-time PCR. The results revealed that FUT1 and FUT2 expression levels w.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017613
- DOI:
- 10.4238/gmr.15017613
Molecular characterization, expression, and functional analysis of chicken TRAF6
Authors: J. Jin, J.S. Ran, C.W. Yang, X.S. Jiang, Y.G. Zhou, Z.Q. Feng, Y. Wang, D. Lan, P. Ren and Y.P. Liu
Tumor necrosis factor receptor-associated factor 6 (TRAF6) is a crucial adaptor molecule of the interleukin-1 receptor/Toll-like receptor (IL-1/TLR) superfamily, which can trigger downstream signaling cascades involved in innate immunity. The function of TRAF6 has been clarified in mammals but is poorly understood in chicken. .. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019138
- DOI:
- 10.4238/gmr16019138
Molecular cloning and single nucleotide polymorphism analysis of IGF2a genes in the common carp (Cyprinus carpio)
Authors: S.Y. Su, Z.J. Dong, J.Q. Qu, Z.Y. Liang, J.Q. Zhang, L.X. Ma, W. Liu, P. Xu and X.H. Yuan
We studied whether two IGF2 transcripts in common carp are similar to those found in zebrafish. The full-length IGF2a cDNA contains a 5'-terminal untranslated region (UTR) of 105 bp, a 3'-terminal UTR of 1358 bp and an open reading frame of 612 bp, which encodes a 206-amino acid protein. A 6614-bp full-length IGF2a DNA molecul.. Read More»
- Genet. Mol. Res. 11(2):
- 0.4238/2012.May.15.3
- DOI:
- 0.4238/2012.May.15.3
Absence of SH2B3 mutation in nonobese diabetic mice
Authors: Y.J. Li, X.Y. Li, X.R. Guo, Y. Li, B.F. Shen, Y.C. Shi and J.Y. Zhang
Type 1 diabetes is a chronic progressive autoimmune disease characterized by mononuclear cell infiltration, with subsequent destruction of insulin-producing β-cells. Studies have identified strong associations between type 1 diabetes and several chromosome regions, including 12q24. Association between type 1 diabetes and .. Read More»
- Genet. Mol. Res. 11(2):
- 2012.May.9.6
- DOI:
- 10.4238/2012.May.9.6
Multiclass microarray data classification based on confidence evaluation
Authors: H.L. Yu, S. Gao, B. Qin and J. Zhao
Microarray technology is becoming a powerful tool for clinical diagnosis, as it has potential to discover gene expression patterns that are characteristic for a particular disease. To date, this possibility has received much attention in the context of cancer research, especially in tumor classification. However, most publishe.. Read More»
- Genet. Mol. Res. 11(2):
- 2012.May.15.6
- DOI:
- 10.4238/2012.May.15.6
Molecular characterization of a mariner-like element in the Atta sexdens rubropilosa genome
Authors: P. Rezende-Teixeira, J.B. do Amaral, F. Siviero and G.M. Machado-Santelli
Mobile elements are widely present in eukaryotic genomes. They are repeated DNA segments that are able to move from one locus to another within the genome. They are divided into two main categories, depending on their mechanism of transposition, involving RNA (class I) or DNA (class II) molecules. The mariner-like elements are.. Read More»
- Genet. Mol. Res. 11(2):
- 2012.May.21.4
- DOI:
- 10.4238/2012.May.21.4
Development of microsatellite markers for the small yellow croaker Larimichthys polyactis (Sciaenidae) by cross-species amplification
Authors: D.Q. Sun, H.Y. Li, T.J. Xu and R.X. Wang
The small yellow croaker (Larimichthys polyactis) is a highly valued fish for human consumption found in the Western Pacific that was considered endangered until recently because of overfishing. We selected microsatellite markers for this species from markers developed for Miichthys miiuy, also of the family Sciaenidae. Among .. Read More»
- Genet. Mol. Res. 11(2):
- 2012.May.21.3
- DOI:
- 10.4238/2012.May.21.3
Seventeen polymorphic microsatellite markers developed for the Javelin goby, Synechogobius hasta (Gobiidae)
Authors: C.-C. Bai, S.-F. Liu, Z.-M. Zhuang, Y.-J. Yuan, H.-B. Liu and F.-Q. Dai
Synechogobius hasta is an important commercial marine fish with distinctive features of rapid growth and short lifespan. We isolated and characterized 17 microsatellite markers for S. hasta using a (GT)13-enriched genomic library. Polymorphism was assessed in 48 individuals from a single population collected from the northern .. Read More»
- Genet. Mol. Res. 11(2):
- 2012.May.18.7
- DOI:
- 10.4238/2012.May.18.7
Development of 18 microsatellite loci for the freshwater snail Bellamya aeruginosa (Mollusca, Gastropoda)
Authors: Q.H. Gu, B.X. Xiong, Y.T. Zhu, Q. Wang and P.S. Shi
Although it is a major freshwater gastropod species, genetic diversity of Bellamya aeruginosa was completely unknown. Eighteen microsatellite loci were isolated and characterized from (AC)15-enriched genomic libraries of the freshwater snail B. aeruginosa. Most of the 18 loci were successfully amplified and high polymorphic information content values were.. Read More»
- Genet. Mol. Res. 11(2):
- 2012.May.18.4
- DOI:
- 10.4238/2012.May.18.4