Animal Genetics
Exceptional material requirement for reproduction in mouse oocytes
Authors: L. Yu1*, S.F. Wang2*, Q.Z. Zhai3*, Y.Q. Yao3, F. Jiang4 and Y.X. Lu1
Limited information on oocytes and fertilization prevents the efficient therapy of patients with infertility. The most important reason for this lack of understanding is a deficiency in research dedicated to oocytes and fertilization. Currently, we are concerned with the role of nutrition in the process of oocyte development to better understand the relat.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.13.21
- DOI:
- 10.4238/2015.November.13.21
Molecular characterization, chromosome mapping, and expression profile of porcine CDC16
Authors: D. Xu, J. Jiang and H. Ma
Cell division cycle16 (CDC16) is a core component among the eight protein subunits of the anaphase-promoting complex (APC). APC is a cyclin degradation system that governs the exit of cells from mitosis. Not much information is available for CDC16 in pig. In this study, a 2284-bp cDNA of porcine CDC16 was obtained by rapid amp.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.19.25
- DOI:
- 10.4238/2015.October.19.25
Molecular characterization, expression, polymorphism of NR5A2 and its relationship with litter size in Hu sheep
Authors: Y.X. Li, J. Zhang, Y. Qian, C.H. Meng, H.L. Wang, X.J. Tao, S. Zhong, S.X. Cao and Q.F. Li
NR5A2 has been implicated in processes as diverse as steroidogenesis, cellular proliferation, ovarian follicular development, ovulation, and fertility in mammals. However, data about the relationship between NR5A2 and prolificacy in mammals are lacking. In the present study, we identified and characterized NR5A2 of Hu sheep, a.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.19.20
- DOI:
- 10.4238/2015.October.19.20
MC1R, KIT, IGF2, and NR6A1 as markers for genetic differentiation in Thai native, wild boars, and Duroc and Chinese Meishan pigs
Authors: P. Klomtong, K. Chaweewan, Y. Phasuk and M. Duangjinda
Mutations in melanocortin 1 receptor (MC1R) gene and v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (KIT) gene have been shown to affect coat color patterns in pigs. Additional functional marker genes, such as insulin like growth factor-2 (IGF2) and orphan nuclear receptor, germ cell nuclear factor (NR6A1), have.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.19.16
- DOI:
- 10.4238/2015.October.19.16
Effect of luteolin on gene expression in mouse H22 hepatoma cells
Authors: J.X. Niu1, H.P. Guo2, H.M. Gan3, L.D. Bao4, J.J. Ren1
The purpose of our study was to observe the effects of luteolin on the expression of the genes ICAM-1, LFA-3, and PCNA in H22 hepatoma tissue. Sixty ICR (Institute of Cancer Research) mice with H22 hepatoma were randomly divided into five groups: a normal saline control group, low-, medium-, and high-dose luteolin groups, and a cyclophosphamide group. The.. Read More»
- Genet. Mol. Res. 14(4):
PPAR�± signal pathway gene expression is associated with fatty acid content in yak and cattle longissimus dorsi muscle
Authors: W. Qin, C.N. Liang, X. Guo, M. Chu, J. Pei, P.J. Bao, X.Y. Wu, T.K. Li and P. Yan
ntramuscular fatty acid (FA) is related to meat qualities such as juiciness, tenderness, palatability, and shear force. PPARα plays an important role in lipid metabolism in the liver and skeletal muscle. This study investigated FA composition in yaks and cattle, in order to ascertain whether a correlation between PPARα signal pathway genes as .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.18.9
- DOI:
- 10.4238/2015.November.18.9
Genetic parameters for milk production traits and breeding goals for Gir dairy cattle in Brazil
Authors: M.A. Prata, L.E. Faro, H.L. Moreira, R.S. Verneque, A.E. Vercesi Filho, M.G.C.D. Peixoto and V.L. Cardoso
To implement an animal breeding program, it is important to define the production circumstances of the animals of interest to determine which traits of economic interest will be selected for the breeding goal. The present study defined breeding goals and proposed selection indices for milk production and quality traits of Gir .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.19.2
- DOI:
- 10.4238/2015.October.19.2
Molecular characterization of a cytosolic manganese superoxide dismutase from the Chinese mitten crab, Eriocheir sinensis
Authors: D.X. Zhao1,2, L.Q. Chen1, J.G. Qin3, C.J. Qin1, H. Zhang1, P. Wu1 and E.C. Li
A cytosolic manganese superoxide dismutase gene (Es-cMnSOD) was cloned from the Chinese mitten crab Eriocheir sinensis, using reverse transcription-polymerase chain reaction and the rapid amplification of cDNA ends. The open reading frame of Es-cMnSOD is 867 bp in length and encodes a 288-amino acid protein without a signal peptide. The calculated molecul.. Read More»
- Genet. Mol. Res. 13(4):
Methylation analysis of CXCR1 in mammary gland tissue of cows with mastitis induced by Staphylococcus aureus
Authors: Y.J. Mao, X.R. Zhu, R. Li, D. Chen, S.Y. Xin, Y.H. Zhu, X.X. Liao, X.L. Wang, H.M. Zhang, Z.P. Yang and L.G. Yang
Mastitis is the most important disease in the global dairy industry, and causes large economic losses. Staphylococcus aureus is one of most common pathogens that cause bovine mastitis. CXCR1 has been implicated as a prospective genetic marker for mastitis resistance in dairy cows; CXCR1 expression significantly increases when .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.19.4
- DOI:
- 10.4238/2015.October.19.4
Genomic selection for slaughter age in pigs using the Cox frailty model
Authors: V.S. Santos, S. Martins Filho, M.D.V. Resende, C.F. Azevedo, P.S. Lopes, S.E.F. Guimar�£es, L.S. Gl�³ria and F.F. Silva
The aim of this study was to compare genomic selection methodologies using a linear mixed model and the Cox survival model. We used data from an F2 population of pigs, in which the response variable was the time in days from birth to the culling of the animal and the covariates were 238 markers [237 single nucleotide polymorph.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.19.5
- DOI:
- 10.4238/2015.October.19.5