Animal Genetics
Identification of genes and pathways related to lipopolysaccharide signaling in duckling spleens
Authors: B. Deng, T. Yu, W. Liu, S.Q. Ye, L.X. Wang, Y. Yang, P. Gong, Z.P. Ran, H.J. Huang and J.H. Wen
Lipopolysaccharide (LPS), the major component of the outer cell wall of Gram-negative bacteria, activates the immune system and threatens the health of livestock and poultry. However, little is known about the genes and pathways involved in the immune response of ducklings to LPS. To elucidate the genes involved in the response of 7-day-old duckling splee.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.16.32
- DOI:
- 10.4238/2015.December.16.32
Utilization of molecular markers for the conservation of blood cockles, Anadara granosa (Arcidae)
Authors: S.Y. Chee , M.N.S. Azizah and M.N. Devakie
We examined genetic variation in blood cockles in an effort to obtain information useful for the sustainability, management, and the stability of this species as a major commodity in the fisheries sector. Ten populations of cockles were sampled from the north to the south of the west coast of peninsular Malaysia. The cockles w.. Read More»
- Genet. Mol. Res. 10(2):
- vol10-2gmr1103
- DOI:
- 10.4238/vol10-2gmr1103
A single nucleotide polymorphism in GABAA receptor isoforms is potentially responsible for isoflurane sensitivity in mice
Authors: X. Wang, Z.G. Song, D.X. Huang, H. Gao, Q. Wang and Z.P. Wang
GABAA receptors are chloride channels in the brain that are activated by binding with g-aminobutyric acid (GABA). The cDNA sequences of GABAA receptor subunits from two strains of mice with different sensitivities to isoflurane were compared to identify nucleotide mutations. Included 80 mice from two strains with different sen.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027340
- DOI:
- 10.4238/gmr.15027340
Population genetic structure of critically endangered salamander (Hynobius amjiensis) in China: recommendations for conservation
Authors: J. Yang, C.S. Chen, S.H. Chen, P. Ding, Z.Y. Fan, Y.W. Lu, L.P. Yu and H.D. Lin
Amji’s salamander (Hynobius amjiensis) is a critically endangered species (IUCN Red List), which is endemic to mainland China. In the present study, five haplotypes were genotyped for the mtDNA cyt b gene in 45 specimens from three populations. Relatively low levels of haplotype diversity (h = 0.524) and nucleotide diver.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027733
- DOI:
- 10.4238/gmr.15027733
Effects of autologous SCF- and G-CSF-mobilized bone marrow stem cells on hypoxia-inducible factor-1 in rats with ischemia reperfusion renal injury
Authors: L.Y. Bi,D.A. Zhao,D.S. Yang,J.G. Guo,B. Liang,R.X. Zhang,J.L. Zhao,H.T. Bai and S.J. Li
To explore the mechanism whereby stem cell factor (SCF) and granulocyte colony-stimulating factor (G-CSF) jointly mobilize bone marrow stem cells (BMSCs) and promote kidney repair, male Sprague-Dawley rats were randomly assigned into 4 groups. In the treatment control group, rats were administered SCF (200 μg· kg-1·day-1) and G-CSF (50 &m.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.27.25
- DOI:
- http://dx.doi.org/10.4238/2015.April.27.25
MicroRNA-21 promotes proliferation of rat hepatocyte BRL-3A by targeting FASLG
Authors: J.J. Li,W.H. Chan,W.Y. Leung,Y. Wang and C.S. Xu
Rat liver regeneration (RLR) induced by partial hepatectomy involves cell proliferation regulated by numerous factors, including microRNAs (miRNAs). miRNA high-throughput sequencing has been established and used to analyze miRNA expression profiles. This study showed that 39 miRNAs were related to RLR through the analysis of miRNA high-throughput sequenci.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.27.30
- DOI:
- http://dx.doi.org/10.4238/2015.April.27.30
Linkage analysis of SNPs in IGFBP-6 and its relation with the body sizes of pig
Authors: X.B. Fang, S.C. Liu, Q.Y. Wu, S.M. Li, Y.Y. Cheng, H.Y. Fu, C. Lu, D. Su, H. Yu and L.L. Hao
Insulin-like growth factor binding protein-6 (IGFBP-6) is a member of the IGFBP family, which is known to be a key factor in regulating the effect of insulin-like growth factor-2 (IGF-2) on the animal growth and development. Gene sequences of 3'-untranslated regions (UTR) and exon 4 of IGFBP-6 may influence the expression and proteolysis of IGFBP-6. In th.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.16.27
- DOI:
- 10.4238/2015.December.16.27
Analysis of polymorphisms in the FUT1 and TAP1 genes and their influence on immune performance in Pudong White pigs
Authors: Y. Zhang, M. Wang, X.Q. Yu, C.R. Ye and J.G. Zhu
FUT1 and TAP1 have been identified as candidate genes that offer resistance against Escherichia coli F18 infection, with the AA genotype in FUT1 and the GG genotype in TAP1 conferring resistance. In order to confirm polymorphisms at FUT1 M307 and TAP1 G729, and evaluate their influence on immunity performance in Pudong White pigs, we performed polymerase .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.16.19
- DOI:
- 10.4238/2015.December.16.19
cDNA, genomic sequence cloning and overexpression of the ribosomal protein S13 gene in the giant panda (Ailuropoda melanoleuca)
Authors: Y. Song, Y.-L. Hou, W.-R. Hou, G.-F. Wu and T. Zhang
The cDNA and the genomic sequence of ribosomal protein S13 (RPS13) of the giant panda (Ailuropoda melanoleuca) was cloned using reverse transcription-polymerase chain reaction (RT-PCR) and touchdown-PCR, respectively. These two sequences were sequenced and analyzed, and the cDNA of the RPS13 gene was overexpressed in Escherich.. Read More»
- Genet. Mol. Res. 10(1):
- vol10-1gmr1000
- DOI:
- 10.4238/vol10-1gmr1000
Toll-like receptor 4 promotes fibrosis in bleomycin-induced lung injury in mice
Authors: X.X. Li, D.Y. Jiang, X.X. Huang, S.L. Guo, W. Yuan and H.P. Dai
The specific role of Toll-like receptor 4 (TLR4) in bleomycin-induced lung fibrosis of mice, a model of human idiopathic pulmonary fibrosis, has not been characterized. We injected bleomycin intratracheally into TLR4 knockout (TLR4-/-) and wild-type (WT) mice. Twenty-one days after injection, mice were sacrificed and their lungs were harvested for patholo.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.21.8
- DOI:
- 10.4238/2015.December.21.8