Animal Genetics
Study of human acellular amniotic membrane loading bone marrow mesenchymal stem cells in repair of articular cartilage defect in rabbits
Authors: P.-F. Liu, L. Guo, D.-W. Zhao, Z.-J. Zhang, K. Kang, R.-P. Zhu and X.-L. Yuan
The aim of this study was to investigate the repair effect of human acellular amniotic membrane (HAAM) loading bone marrow mesenchymal stem cells (BMSCs) on articular cartilage defect in rabbits. Rabbit BMSCs were isolated and cultured, and they were then inoculated on HAAM to prepare the complex of HAAM and BMSCs. Twenty-four.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.September.29.12
- DOI:
- 10.4238/2014.September.29.12
Active vitamin D3, 1,25-(OH)2D3, protects against macrovasculopathy in a rat model of type 2 diabetes mellitus
Authors: R. Ma, X.L. Deng, G.L. Du, C. Li, S. Xiao, Y. Aibibai and J. Zhu
To investigate the protective effect of the active form of vitamin D3, 1,25-(OH)2D3, on macrovasculopathy in rats with type 2 diabetes mellitus (T2DM), 8-week-old male Sprague-Dawley rats were randomly divided into control group, T2DM group, and treatment group. The T2DM model was established after 6 weeks by administering an .. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028113
- DOI:
- 10.4238/gmr.15028113
Effect of dietary Bacillus subtilis on proportion of Bacteroidetes and Firmicutes in swine intestine and lipid metabolism
Authors: C. Cui, C.J. Shen, G. Jia and K.N. Wang
The ratio of Bacteroidetes and Firmicutes bacterial groups in the gut can affect the ability to absorb nutrients. We investigated the effect of probiotic Bacillus subtilis supplementation of diets on growth performance, fat deposition, blood lipids, copy numbers, and percentage of Bacteroidetes and Firmicutes in cecal contents, as well as mRNA expression .. Read More»
- Genet. Mol. Res. 12(2):
- 2013.May.23.1
- DOI:
- 10.4238/2013.May.23.1
Candidate gene region for control of rib eye area in Canchim beef cattle
Authors: S.L. Meirelles, G.V. Gouveia, G. Gasparin, M.M. Alencar, J.J.S. Gouveia and L.C.A. Regitano
Investigation of molecular marker effects on production traits is essential to define marker assisted selection strategies in beef cattle. We looked for a possible association of molecular markers and backfat thickness (BFT) and rib eye area (REA) in Canchim (5/8 Charolais + 3/8 Zebu) and MA (offspring of Charolais bulls and 1.. Read More»
- Genet. Mol. Res. 10(2):
- vol10-2gmr1175
- DOI:
- 10.4238/vol10-2gmr1175
Development of an improved rat model of dual graft liver transplantation with long-term survival
Authors: X.-J. Xie, Y.-F. Ye, Y. He, H.-Y. Xie, L. Zhou, Y. Wang, C.-Y. Xing and S.-S. Zheng
Dual graft liver transplantation has been demonstrated to be feasible as well as effective in increasing the donor pool and in preventing the potential for small-for-size syndrome. However, little is known about the pathophysiological and immune processes following dual graft liver transplantation due to the lack of appropriat.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.September.29.16
- DOI:
- 10.4238/2014.September.29.16
Development of new polymorphic microsatellite markers in topmouth culter (Culter alburnus) and determination of their applicability in Culter mongolicus
Authors: P.-Z. Qi, C.-X. Xie, B.-Y. Guo, C.-W. Wu, S.-M. Lu and Y.-J. Duan
Fifteen new polymorphic microsatellite markers were developed for Culter alburnus. In 32 individuals representing a wild population of the Danjiangkou Reservoir, Hubei, China, the number of alleles at these loci varied between 2 and 10, with an average of 5.5. The average observed and expected heterozygosities were 0.664 and 0.681, respectively. The polym.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.May.21.7
- DOI:
- 10.4238/2013.May.21.7
Breeding value accuracy estimates for growth traits using random regression and multi-trait models in Nelore cattle
Authors: A.A. Boligon, F. Baldi, M.E.Z. Mercadante2, R.B. Lobo, R.J. Pereira and L.G. Albuquerque
We quantified the potential increase in accuracy of expected breeding value for weights of Nelore cattle, from birth to mature age, using multi-trait and random regression models on Legendre polynomials and B-spline functions. A total of 87,712 weight records from 8144 females were used, recorded every three months from birth .. Read More»
- Genet. Mol. Res. 10(2):
- vol10-2gmr1087
- DOI:
- 10.4238/vol10-2gmr1087
Distribution of LIM domain kinase 1 in the olfactory bulb, cerebral cortex, hippocampus, and cerebellum of the App/PS+/- mice
Authors: L. An, J. Liu, W.W. Li, Y.J. Shi, X.H. Lin, D.M. Yu, J.B. Deng and X.Q. Ren
LIM domain kinase 1 (LIMK1), an actin-binding kinase, can phosphorylate and inactivate its substrates, and can regulate long-term memory and synaptic plasticity. Both β-amyloid precursor protein (App) and presenilin (PS) are functional degeneration factors during early neuronal development, and are considered as potential factors that contribute to t.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.16.24
- DOI:
- 10.4238/2015.December.16.24
Phylogenetic study and barcoding of the blood cockle, Tegillarca granosa, found on the west coast of peninsular Malaysia using the COI gene
Authors: S.Y. Chee, M.N. Devakie, M.N. Siti Azizah
Blood cockles are among the most economically important brackish water invertebrates found in Malaysia. However, our knowledge of blood cockle phylogeny and systematics is rudimentary, especially for the species Tegillarca granosa. It is unclear, for instance, whether the cockles occurring on the west coast of peninsular Malay.. Read More»
- Genet. Mol. Res. 10(2):
Effects of nucleotide usage on the synonymous codon usage patterns of biofilm-associated genes in Haemophilus parasuis
Authors: L.Y. Wang, L.N. Ma and Y.S. Liu
To provide a new perspective on the evolutionary characteristics shaping the genetic diversity of Haemophilus parasuis biofilms, the relative synonymous codon usage values, codon usage bias values, effective number of codons (ENC) values, codon adaptation index (CAI) values, and the base components were calculated. Our objecti.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027226
- DOI:
- 10.4238/gmr.15027226