Animal Genetics
Characterization of 10 novel microsatellite loci for the brown marbled grouper, Epinephelus fuscoguttatus (Serranidae)
Authors: M.A.A. Mokhtar, M.N. Normah, S.V. Kumar and S.N. Baharum
Epinephelus fuscoguttatus is a commercially important marine fish species in southeast Asia. Due to overfishing and water pollution, this species has been declared as near-threatened. Thus, to provide information to help maintain and preserve the species, microsatellites were developed, using an enriched genomic library method.. Read More»
- Genet. Mol. Res. 10(2):
- vol10-2gmr1117
- DOI:
- 10.4238/vol10-2gmr1117
Protective effect of icariin on kidney in 5/6 nephrectomized rats and its mechanism
Authors: S.R. Liang, J.W. Bi, Z.L. Guo, Y. Bai and Z. Hu
The aim of this study was to investigate the renal protective effect of icariin in 5/6 nephrectomized rats and the molecular mechanisms involved. Forty male Sprague-Dawley rats were randomly divided into 5 groups: sham-operated group, 5/6 nephrectomy model group, icariin groups (20 and 40 mg/kg), and benazepril group. After 12.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.August.25.10
- DOI:
- 10.4238/2014.August.25.10
Polymorphisms in the delta-like 2 homolog gene and their association with growth and meat-quality traits in Qinchuan cattle
Authors: N. Yang, L.S. Zan, Y.K. Li, J.B. Gao, X.H. Ma, C.Z. Fu, H. Wang and C. Adoligbe
The delta-like 2 homolog (DLK2) modulates adipogenesis, hematopoiesis, osteogenesis, and other cell-differentiation processes. In the present study, we detected potential polymorphisms in the DLK2 gene in 604 individuals of Qinchuan cattle by using PCR-RFLP and DNA-sequencing methods. Herein, we identified five novel single-nu.. Read More»
- Genet. Mol. Res. 13(1):
- 2014.March.24.20
- DOI:
- 10.4238/2014.March.24.20
Genetic assessment of the Atlantic Forest bristle porcupine, Chaetomys subspinosus (Rodentia: Erethizontidae), an endemic species threatened with extinction
Authors: C.G. Oliveira, R.A. Martinez, G.A.F. Gin�©, D.M. Faria and F.A. Gaiotto
The bristle-spined porcupine, Chaetomys subspinosus, an endemic rodent from Atlantic Forest, was considered to be abundant in the recent past, but population reductions due to habitat loss and expansion of human activities caused this species to be included in the “vulnerable” category of the World Conservation Uni.. Read More»
- Genet. Mol. Res. 10(2):
- vol10-2gmr1039
- DOI:
- 10.4238/vol10-2gmr1039
A novel polymorphism of the GDF10 gene and its association with body measurement traits in Chinese indigenous cattle
Authors: C. Adoligbe, L.S. Zan, H.B. Wang and J.A. Ujjan
Body measurement traits are known to play numerous important roles in the assessment of productivity and economic value. They are influenced by several factors, among which genetic factors are predominant. The gene GDF10 is involved in skeletal morphogenesis and is associated with body measurement traits. It may be an importan.. Read More»
- Genet. Mol. Res. 10(2):
- vol10-2gmr989
- DOI:
- 10.4238/vol10-2gmr989
PPAR-�³ agonist pioglitazone affects rat gouty arthritis by regulating cytokines
Authors: R.-C. Wang and D.-M. Jiang
The objective was to study peroxisome proliferator-activated receptor gamma (PPARγ) agonist pioglitazone regulation effect and its mechanism of expression of cytokines on acute gouty arthritis synovial in rats. Rats with unilateral ankle were injected with artificial monosodium urate (MSU) crystals to make the acute gout.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.August.28.2
- DOI:
- 10.4238/2014.August.28.2
Molecular diagnosis of Eimeria species affecting naturally infected Gallus gallus
Authors: F.S. Carvalho, A.A. Wenceslau, M. Teixeira and G.R. Albuquerque
We used PCR to test various protocols and define a technique for DNA extraction directly from chicken-shed stool samples for the identification of Eimeria species that parasitize birds. It was possible to extract and amplify DNA of seven Eimeria species from field stool samples, using both protocols tested; extractions made wi.. Read More»
- Genet. Mol. Res. 10(2):
Comparative proteomic changes of differentially expressed whey proteins in clinical mastitis and healthy yak cows
Authors: X. Li, X.Z. Ding, Y.L. Wan, Y.M. Liu and G.Z. Du
Under the traditional grazing system on the Qinghai-Tibetan Plateau, the amount of milk in domesticated yak (Bos grunniens) with clinical mastitis decreases and the milk composition is altered. To understand the mechanisms of mammary gland secreted milk and disease infection, changes in the protein composition of milk during c.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.August.28.4
- DOI:
- 10.4238/2014.August.28.4
Isolation and characterization of 21 novel polymorphic microsatellite loci in the Chinese soft-shelled turtle Pelodiscus sinensis
Authors: X.J. Bu, L. Liu, L. Wang and L.W. Nie
Twenty-one novel polymorphic microsatellite loci were isolated from the Chinese soft-shelled turtle, Pelodiscus sinensis (Trionychidae). This is a commonly consumed Asian species, especially in China, where it is reared in large numbers on farms. We screened 34 unrelated individuals from Wuhu of Anhui province in China and det.. Read More»
- Genet. Mol. Res. 10(2):
- vol10-2gmr1119
- DOI:
- 10.4238/vol10-2gmr1119
Dynamics of morphological evolution in experimental Escherichia coli populations
Authors: F. Cui and B. Yuan
Here, we applied a two-stage clonal expansion model of morphological (cell-size) evolution to a long-term evolution experiment with Escherichia coli. Using this model, we derived the incidence function of the appearance of cell-size stability, the waiting time until this morphological stability, and the conditional and unconditional probabilities of morph.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038991
- DOI:
- 10.4238/gmr.15038991