Animal Genetics
Gene expression profiles in the cerebellum of transgenic mice over expressing the human FMR1 gene with CGG repeats in the normal range
Authors: J.J. FernÃ?¡ndez, R. MartÃ?Ânez, E. AndÃ?ºjar, M. PÃ?©rez-Alegre, A. Costa, V. Bonilla-Henao, F. Sobrino, C.Ã?Â?. Pintado and E. Pintado
Modifications in the GABA pathway are considered to be responsible for motor alterations in animal models for fragile X-associated tremor ataxia syndrome. We analyzed the expression profile in the cerebellum in a transgenic mouse model that over expresses the human FMR1 gene with CGG repeats in the normal range. We used the &l.. Read More»
- Genet. Mol. Res. 11(1):
- 2012.March.1.4
- DOI:
- 10.4238/2012.March.1.4
Chromosomal characteristics and karyotype evolution of Oxyopidae spiders (Araneae, Entelegynae)
Authors: L.M. St�¡vale, M.C. Schneider, A.D. Brescovit and D.M. Cella
We made a cytogenetic analysis of four species of Oxyopidae and compared it with the karyotype data of all species of this family. In Hamataliwa sp, the mitotic cells showed 2nâÃ?Â?Ã?Â? = 26+X1X2 and telocentric chromosomes. The 2nâÃ?Â?Ã?Â? = 28, which has been described for only one oxyopid spider, is the highest .. Read More»
- Genet. Mol. Res. 10(2):
- vol10-2gmr1084
- DOI:
- 10.4238/vol10-2gmr1084
Polymorphic microsatellite loci for the Japanese anchovy Engraulis japonicus (Engraulidae)
Authors: L. Lin, L. Zhu, S.-F. Liu, Y.-Q. Su and Z.-M. Zhuang
We isolated and characterized 14 polymorphic microsatellite loci in the Japanese anchovy (Engraulis japonicus) using a (GT)13-enriched genomic library. The numbers of alleles per locus ranged from 6 to 31, with a mean of 17.8. The observed and expected heterozygosities ranged from 0.180 to 0.949 and from 0.172 to 0.966, with means of 0.731 and 0.825, resp.. Read More»
- Genet. Mol. Res. 10(2):
- vol10-2gmr1085
- DOI:
- 10.4238/vol10-2gmr1085
Effects of curcumin on hippocampal expression of NgR and axonal regeneration in A�²-induced cognitive disorder rats
Authors: H.L. Yin, Y.L. Wang, J.F. Li, B. Han, X.X. Zhang, Y.T. Wang and S. Geng
Curcumin has been widely used for the prevention and treatment of Alzheimer’s disease (AD), but its mechanism is still not clear. Inhibitory factors of axonal regeneration have been shown to cause a series of pathophysiological changes in the early period of AD. In this study, the co-receptor (Nogo receptor; NgR) of thre.. Read More»
- Genet. Mol. Res. 13(1):
- 2014.March.24.8
- DOI:
- 10.4238/2014.March.24.8
Detection of differentially expressed genes in the longissimus dorsi of Northeastern Indigenous and Large White pigs
Authors: Y. Gao, Y.H. Zhang, H. Jiang, S.Q. Xiao, S. Wang, Q. Ma, G.J. Sun, F.J. Li, Q. Deng, L.S. Dai, Z.H. Zhao, X.S. Cui, S.M. Zhang, D.F. Liu and J.B. Zhang
Recent attention in pig breeding programs has focused on the improvement of pork quality in response to increasing consumer demands. Compared to the fatty-type Northeastern Indigenous (Chinese) breed of pigs, the lean-type Large White has lower intramuscular fat and inferior eating quality from the perspective of the Chinese c.. Read More»
- Genet. Mol. Res. 10(2):
Effect of fragmentation on the natural genetic diversity of Theobroma speciosum Willd. ex Spreng. populations
Authors: T.L. Varella, A.A.B. Rossi, J.F.E. Dardengo, G.F. Silveira, M.D.A. Souza and M.L.S. Carvalho
t fragmentation reduces the effective size of natural populations, isolates individuals in the landscape, and, consequently, changes species’ mating systems by increasing the degree of relatedness between individuals and inbreeding. Investigating the impact of habitat degradation on forest fragments helps to assess the g.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15048630
- DOI:
- 10.4238/gmr15048630
Development and characterization of 70 novel microsatellite markers for the sea cucumber (Apostichopus japonicus)
Authors: W. Peng, Z.M. Bao, H.X. Du, J.J. Yan, L.L. Zhang and J.J. Hu
The sea cucumber (Apostichopus japonicus) is an important item in Asian cuisine. It is currently produced through aquaculture, especially in China, after being overexploited in the wild in the 1990s. We isolated 70 novel polymorphic microsatellite loci using an enrichment-colony hybridization protocol. All loci were characteri.. Read More»
- Genet. Mol. Res. 11(1):
- 2012.February.24.2
- DOI:
- 10.4238/2012.February.24.2
Identification and characterization of differentially expressed genes during incompatible interaction between the foliar rust Melampsora larici-populina and poplar
Authors: Z.J. Chen, Z.M. Cao and Z.D. Yu
Poplars are extensively cultivated worldwide, and their susceptibility to the foliar rust fungus leads to considerable damages in plantations. To better understand the molecular basis of poplar responses to the foliar rust, suppression subtractive hybridization was used to identify the potential important or novel genes involv.. Read More»
- Genet. Mol. Res. 13(1):
- 2014.March.24.12
- DOI:
- 10.4238/2014.March.24.12
Genome-wide association study on growth traits in Colombian creole breeds and crossbreeds with Zebu cattle
Authors: R. MartÃ?Ânez, Y. GÃ?³mez and J.F.M. Rocha
Whole genome selection represents an important tool for improving parameters related to the production of livestock. In order to build genomic selection indexes within a particular breed, it is important to identify polymorphisms that have the most significant association with a desired trait. A genome-wide marker association .. Read More»
- Genet. Mol. Res. 13(3):
- 2014.August.25.5
- DOI:
- 10.4238/2014.August.25.5
Cytogenetics and morphology of two tortoise species of the genus Chelonoidis (Fitzinger, 1835) (Testudines)
Authors: T.L. Silva
The reptiles were reduced in number of species since the time that they ruled the earth until today. The tortoises have been poorly studied, particularly their morphological and cytogenetic features. We examined the species Chelonoidis carbonaria and C. denticulata, terrestrial tortoises representative of two contrasting biome.. Read More»
- Genet. Mol. Res. 10(2):
- vol10-2ta034
- DOI:
- 10.4238/vol10-2ta034