Animal Genetics
Detection of Jaagsiekte sheep retrovirus in the peripheral blood during the pre-clinical period of ovine pulmonary adenomatosis
Authors: Y. Liu, Y.F. Zhang, X.L. Sun and S.Y. Liu
The envelope protein (Env) of the Jaagsiekte sheep retrovirus (JSRV) is known to be a unique oncoprotein responsible for inducing ovine pulmonary adenocarcinoma (OPA). The objective of this study was to prepare a specific monoclonal antibody (mAb) against the JSRV Env protein using bioinformatic analysis. According to the stru.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038521
- DOI:
- 10.4238/gmr.15038521
Simultaneous presence of bovine papillomavirus and bovine leukemia virus in different bovine tissues: in situ hybridization and cytogenetic analysis
Authors: A. Yaguiu, M.L.Z. Dagli, E.H. Birgel Jr., B.C.A. Alves Reis,O.P. Ferraz, E.M. Pituco6, A.C. Freitas, W. Be�§ak and R.C. Stocco
Bovine papillomavirus (BPV) DNA sequences were detected in different tissues, in addition to epithelium. Cytogenetic abnormalities were observed in blood lymphocytes. The presence of more than one virus in a single tissue is a difficult aspect to evaluate,especially when the DNA sequences are detected in tissues that are not s.. Read More»
- Genet. Mol. Res. 7(2):
Overexpression of the A-FABP gene facilitates intermuscular fat deposition in transgenic mice
Authors: Z.W. Liu, H.L. Fan, X.F. Liu, X.B. Ding, T. Wang, G.N. Sui,G.P. Li and H. Guo
Adipocyte fatty acid-binding protein (A-FABP), the most abundant FABP in adipocytes, controls fatty acid uptake, transport, and metabolism in fat cells. We constructed a transgenic mice model that overexpressed the cattle A-FABP gene to investigate the relationship between A-FABP expression and intermuscular fat deposition. There was no significant differ.. Read More»
- Genet. Mol. Res. 14(1):
- http://dx.doi.org/2015.March.31.4
- DOI:
- http://dx.doi.org/10.4238/2015.March.31.4
Programmed cell death in salivary glands of Drosophila arizonae and Drosophila mulleri
Authors: P. Ianella, M.T.V. Azeredo-Oliveira and M.M. Itoyama
Programmed cell death (PCD) in insect metamorphosis assumes a great diversity of morphology and controlling processes that are still not well understood. With the objective of obtaining information about the PCD process, salivary glands of Drosophila arizonae and D. mulleri were studied during larval-pupal development. From the results, it can be conclude.. Read More»
- Genet. Mol. Res. 7(2):
- vol7-2gmr412
- DOI:
- 10.4238/vol7-2gmr412
Induction of mitotic crossing-over in diploid strains of Aspergillus nidulans using low-dose X-rays
Authors: L.B. Stoll, F.C.A. Cremonesi, L.T.A. Pires, T.D. Zucchi andT.M.A.D. Zucchi4,
As a contribution towards detecting the genetic effects of low doses of genotoxic physical agents, this paper deals with the consequences of low-dose X-rays in the Aspergillus nidulans genome. The irradiation doses studied were those commonly used in dental clinics (1-5 cGy). Even very low doses promoted increased mitotic crossing-over frequencies in dipl.. Read More»
- Genet. Mol. Res. 7(2):
- vol7-2gmr414
- DOI:
- 10.4238/vol7-2gmr414
Cloning, sequencing and antigenic characterization of rVirB9 of Anaplasma marginale isolated from Paran�¡ State, Brazil
Authors: M.C. Vidotto, E.J. Ven�¢ncio and O. Vidotto
Anaplasma marginale, a tick-borne bacterium, causes bovine anaplasmosis responsible for significant economic losses in tropical and subtropical regions worldwide. Various major outer membranes have been described, and VirB9, a type IV secretion system protein, has been recently indicated as a candidate in vaccine development against anaplasmosis. The virB.. Read More»
- Genet. Mol. Res. 7(2):
Karyotype analysis of mithun (Bos frontalis) and mithun bull x Brahman cow hybrids
Authors: K.-X. Qu, Z.-X. He, W.-H. Nie, J.-C. Zhang, X.-D. Jin, G.-R. Yang, X.-P. Yuan, B.-Z. Huang, Y.-P. Zhang and L.-S. Zan
We examined the cytogenetics of mithun (Bos frontalis), a domesticated version of the Asian gaur, and hybrids (F1 generation) produced by artificial insemination of Brahman cows (Bos indicus) with mithun semen. Reproductive potential was also examined in the F1 generation and a backcrossed heifer for utilization of heterosis. .. Read More»
- Genet. Mol. Res. 11(1):
- http://dx.doi.org/2012.January.19.1
- DOI:
- http://dx.doi.org/10.4238/2012.January.19.1
Mutational analysis of genes p14ARF, p15INK4b, p16INK4a, and PTEN in human nervous system tumors
Authors: L.O. Almeida, A.C. Cust�³dio, J.J. Ara�ºjo, J.A. Rey,J.R.W. Almeida, M.J. Santos, C.A. Clara and C. Casartelli
The cancer is one of the most common and severe problems in clinical medicine, and nervous system tumors represent about 2% of the types of cancer. The central role of the nervous system in the maintenance of vital activities and the functional consequences of the loss of neurons can explain how severe brain cancers are. The c.. Read More»
- Genet. Mol. Res. 7(2):
- vol7-2gmr445
- DOI:
- 10.4238/vol7-2gmr445
Initial stage of development and migratory behavior of Toxocara canis larvae in BALB/c mouse experimental model
Authors: M.L. Camparoto, B. Fulan, C.M. Colli, M.L. Paludo,A.L. Falavigna-Guilherme and M.A. Fernandez
In the present study, the initial developmental stage of Toxocara canis eggs and larvae, and number of recovered larvae from BALB/c mouse-infected organs are described. In vitro culture of T. canis detects the frequencies of interphasic, mitotic and embryonated eggs only within a 7-day period. Analysis by egg counting was carried out for 32 days. The resu.. Read More»
- Genet. Mol. Res. 7(2):
- vol7-2gmr443
- DOI:
- 10.4238/vol7-2gmr443
Genotoxicity evaluation in chronic renal patients undergoing hemodialysis and peritoneal dialysis, using the micronucleus test
Authors: J.M. Roth, R.G. Restani, T.T.S. Gon�§alves, S.L.S. Sphor,A.B. Ness, M.G. Martino-Roth and G.L. Garcias
Patients with chronic renal disease have an increased incidence of cancer. It is well known that long periods of hemodialysis treatment are linked to DNA damage due to oxidative stress. This genotoxic effect may cause the loss of chromosome fragments, or even entire chromosomes, which form micronuclei after cell division, and .. Read More»
- Genet. Mol. Res. 7(2):