Animal Genetics
Identification of COL6A1 as a differentially expressed gene in human astrocytomas
Authors: A. Fujita, J.R. Sato, F. Festa, L.R. Gomes, S.M. Oba-Shinjo,S.K.N. Marie, C.E. Ferreira and M.C. Sogayar
Diffuse infiltrating gliomas are the most common tumors of the central nervous system. Gliomas are classified by the WHO according to their histopathological and clinical characteristics into four classes: grade I (pilocytic astrocytoma), grade II (diffuse astrocytoma), grade III (anaplastic astrocytoma), and grade IV (gliobla.. Read More»
- Genet. Mol. Res. 7(2):
- vol7-2gmr432
- DOI:
- 10.4238/vol7-2gmr432
Cytogenetic studies in Brazilian marine Sciaenidae and Sparidae fishes (Perciformes)
Authors: I.V. Accioly and W.F. Molina
Fishes from the families Sciaenidae and Sparidae, the former comprising coastal species associated with shallow waters on the continental shelf and the latter composed of typically marine species, are of significant economic value. Karyotypic data are available for about 20% of the total number of species in these groups. In t.. Read More»
- Genet. Mol. Res. 7(2):
- vol7-2gmr427
- DOI:
- 10.4238/vol7-2gmr427
Comparative cytogenetics study between Triatoma maculata and Triatoma pseudomaculata (Triatominae, Heteroptera)
Authors: Weverson Luciano Pires
Triatomines are vectors of the protozoan Trypanosoma cruzi, the etiological agent of Chagas’ disease. These hematophagous insects belong to the order Heteroptera and to the family Reduviidae. Disseminated throughout large portions of Brazil and of other Latin American countries, Chagas’ disease is a serious and imp.. Read More»
- Genet. Mol. Res. 7(2):
Analysis of key genes and pathways involved in acute lung injury in a mouse model
Authors: Q.H. Han, N. Han, Y.Z. Liu, Q.H. Jin, Q.Y. Lu and Z.C. Li
A mouse model of acute lung injury (ALI) was chosen in this study to explore the key genes and pathways involved in the process of ALI with microarray technology. Gene expression microarray data were downloaded from the Gene Expression Omnibus database. Mice from the experimental group were further divided into 6 subgroups, wh.. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.June.18.1
- DOI:
- http://dx.doi.org/10.4238/2014.June.18.1
Identification and abundance of miRNA in chicken hypothalamus tissue determined by Solexa sequencing
Authors: G.R. Sun, M. Li, G.X. Li, Y.D. Tian, R.L. Han and X.T. Kang
We used Solexa sequencing technology to identify and determine the abundance of miRNAs and compared the characteristics and expression patterns of miRNA of 1-day-old and 36-week-old chicken hypothalamuses. We obtained 17,825,753 and 10,928,745 high-quality reads from 36-week-old and 1-day-old chickens, respectively. Three hund.. Read More»
- Genet. Mol. Res. 11(4):
- 2012.October.2.2
- DOI:
- 10.4238/2012.October.2.2
Mitotic behavior in root tips of Brachiaria genotypes with meiotic chromosome elimination during microsporogenesis
Authors: M.F. Felismino, N. Silva, M.S. Pagliarini and C.B. Valle
Three accessions of Brachiaria brizantha, three of B. humidicola, and two interspecific hybrids between B. ruziziensis and B. brizantha were analyzed with regard to their mitotic behavior in root tips. All these genotypes revealed chromosome elimination or lack of chromosome affinity in previous analyses of microsporogenesis. .. Read More»
- Genet. Mol. Res. 7(2):
- vol7-2gmr437
- DOI:
- 10.4238/vol7-2gmr437
Repair of articular cartilage defects by tissue-engineered cartilage constructed with adipose-derived stem cells and acellular cartilaginous matrix in rabbits
Authors: Z.J. Wang, R.Z. An, J.Y. Zhao, Q. Zhang, J. Yang, J.B. Wang, G.Y. Wen, X.H. Yuan, X.W. Qi, S.J. Li and X.C. Ye
After injury, inflammation, or degeneration, articular cartilage has limited self-repair ability. We aimed to explore the feasibility of repair of articular cartilage defects with tissue-engineered cartilage constructed by acellular cartilage matrices (ACMs) seeded with adipose-derived stem cells (ADSCs). The ADSCs were isolat.. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.June.18.2
- DOI:
- http://dx.doi.org/10.4238/2014.June.18.2
Snail-induced epithelial-mesenchymal transition in gastric carcinoma cells and generation of cancer stem cell characteristics
Authors: Y.J. Yang, Z.B. Li, G.R. Zhang, L.J. Wu, J.Y. Yu, L.J. Hu, Y.L. Zhou, H.D. Wang and D. Liang
Biological changes in Snail-overexpressed SGC7901 cells were studied by establishing a pEGFP-C1-Snail carrier. The significance of Snail in epithelial-mesenchymal transition (EMT) as well as the invasion and metastatic capacity of gastric cancer cells was also discussed; moreover, we attempted to verify the probable cancer ste.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038510
- DOI:
- 10.4238/gmr.15038510
Cytogenetic analysis in the spermatogenesis of Triatoma melanosoma (Reduviidae; Heteroptera)
Authors: V.B. Bardella, M.T.V. Azeredo-Oliveira and E. Tartarotti
Triatomines are of great concern in public health because they are vectors of Chagas’ disease. This study presents an analysis of the species Triatoma melanosoma. The cytogenetic characteristics of triatomines include holocentric chromosomes, post-reductional meiosis in the sex chromosomes and nucleolar fragmentation in .. Read More»
- Genet. Mol. Res. 7(2):
- vol7-2gmr411
- DOI:
- 10.4238/vol7-2gmr411
An enhancer/promoter combination strengthens the expression of blood-coagulation factor VIII in non-viral expression vectors
Authors: V. Pican�§o-Castro, E.M.S. Russo-Carbolante, A.M. Fontes,A.C. Fernandes and D.T. Covas
We explored the potential of fusion of hepatic locus control region 1 (HCR-1) with HCR-2 to express B-domain-deleted human factor VIII (FVIII) in four cell lines. B-domain-deleted human FVIII expression was controlled by HCR-1/HCR-2, followed by liver specific and ubiquitous promoters. Chimera enhancer HCR-1/HCR-2, followed by.. Read More»
- Genet. Mol. Res. 7(2):
- vol7-2gmr447
- DOI:
- 10.4238/vol7-2gmr447