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Plant Genetics   Research Article

Characterization of Genetic Diversity and Linkage Disequilibrium of ZmNAC33 in Maize

Authors: Wenping Liu, Chunxiao Zhang, Shufang Li, Fengxue Jin, Wanjun Li, Xiaohui Li

The maize NAC gene, encoding a NAC domain transcription factor, plays vital roles in the growth process of maize under abiotic stresses. To investigate the response of ZmNAC33 to salinity stress, we analyzed the expression of the ZmNAC33 gene in roots and leaves of three-leaf stage seedlings among maize inbred lines. The resul.. Read More»

Genet. Mol. Res. 17(1):
gmr16039879
DOI:
10.4238/gmr16039879
Plant Genetics   Research Article

Roles of the bZIP gene family in rice

Authors: Z.G. E, Y.P. Zhang, J.H. Zhou and L. Wang

The basic leucine zipper (bZIP) genes encode transcription factors involved in the regulation of various biological processes. Similar to WRKY, basic helix-loop-helix, and several other groups of proteins, the bZIP proteins form a superfamily of transcription factors that mediate plant stress responses. In this review, we pres.. Read More»

Genet. Mol. Res. 13(2):
2014.April.16.11
DOI:
10.4238/2014.April.16.11
Medical Genetics   Research Article

Analysis of differentially expressed genes in malignant biliary strictures

Authors: D.C. Qi, B. Wu, S.L. Tao, J. Zhou, H.X. Qian and D. Wang

Microarray data were collected from bile duct samples from subjects with malignant biliary strictures by endoscopic retrograde cholangiopancreatography to screen for key genes associated with this disease. A predicted interaction network was constructed for these genes to interpret their functions. The gene expression dataset .. Read More»

Genet. Mol. Res. 13(2):
2014.April.8.10
DOI:
10.4238/2014.April.8.10
Plant Genetics   Research Article

Genome-wide analysis of the auxin response factor gene family in cucumber

Authors: S.Q. Liu and L.F. Hu

Auxin response factors (ARFs) participate in the transcriptional regulation of a series of biological processes related to growth and development. The ARF genes comprise a large multigene family in plants. Recently, a draft of the full cucumber (Cucumis sativus) genome assembly has been released; however, none of the ARF genes have been characterized. We .. Read More»

Genet. Mol. Res. 12(4):
2013.April.2.1
DOI:
10.4238/2013.April.2.1
Human Genetics   Research Article

Gli1 expression in pancreatic ductal adenocarcinoma and its clinical significance

Authors: Y. Abula, C. Yi, X.-Y. Wang, M. Wang, R.-Y. Qin, Y.-Q. Guo, H. Lin and H.-J. Li

The aim of this study was to explore the correlation between the expression levels of Gli1 and p53 in pancreatic ductal adenocarcinoma (PDAC) and its pathological significance. Immunohistochemistry (IHC) was employed to measure the expression level of Gli1 and p53 in 85 sets of paraffin-embedded PDAC and corresponding para-car.. Read More»

Genet. Mol. Res. 14(4):
2015.October.9.21
DOI:
10.4238/2015.October.9.21
Human Genetics   Research Article

LITAF, DUSP1 and HHEX expression in mesenchymal stem cells from patients with psoriasis.

Authors: W.J. Chang, X.P. Niu, R.X. Hou, J.Q. Li, R.F. Liu, Q. Wang1, C.F. Wang,X.H. Li, G.H. Yin and K.M. Zhang

Psoriasis is a common chronic relapsing inflammatory skin disease, in which mesenchymal stem cells (MSCs) have been hypothesized to play an important role in abnormal localized inflammation and vascular proliferation observed in skin lesions. Previous studies have revealed abnormal gene expression patterns, DNA methylation sta.. Read More»

Genet. Mol. Res. 14(4):
2015.December.1.31
DOI:
10.4238/2015.December.1.31
Medical Genetics   Research Article

Combination of multiple gene markers to detect circulating tumor cells in the peripheral blood of patients with non-small cell lung cancer using real-time PCR

Authors: M. Ding, X. Li and T. Qiu

Our study aims to determine the clinical significance of human telomerase reverse transcriptase (hTERT), S-phase kinase-associated protein 2 (Skp2) and thyroid transcription factor-1 (TTF-1) mRNA expressions in peripheral blood (PB) of patients with non-small cell lung cancer (NSCLC). Real-time polymerase chain reaction was used to investigate the gene ex.. Read More»

Genet. Mol. Res. 14(4):
2015.October.21.24
DOI:
10.4238/2015.October.21.24
Plant Genetics   Research Article

Genomic identification of group A bZIP transcription factors and their responses to abiotic stress in carrot

Authors: F. Que, G.L. Wang, Y. Huang, Z.S. Xu, F. Wang and A.S. Xiong

The basic-region/leucine-zipper (bZIP) family is one of the major transcription factor (TF) families associated with responses to abiotic stresses. Many members of group A in this family have been extensively examined and are reported to perform significant functions in ABA signaling as well as in responses to abiotic stresses. In this study, 10 bZIP fact.. Read More»

Genet. Mol. Res. 14(4):
2015.October.26.24
DOI:
10.4238/2015.October.26.24
Plant Genetics   Research Article

Cloning and transformation of INDUCER of CBF EXPRESSION1 (ICE1) in tomato

Authors: X.H. Yu, J.X. Juan, Z.L. Gao, Y. Zhang, W.Y. Li and X.M. Jiang

The tomato plant (Solanum lycopersicum Mill.) is sensitive to cold, and low field temperatures can result in shortened growth periods and decreased crop yield. Transcription of CRT/DRE-binding factor (CBF) is regulated by INDUCER of CBF EXPRESSION1 (ICE1). CBF activates many downstream genes that confer cold tolerance on plants. ICE1 has been used in gene.. Read More»

Genet. Mol. Res. 14(4):
2015.October.26.9
DOI:
10.4238/2015.October.26.9
Human Genetics   Research Article

JNK pathway and relative transcriptional factor were involved in ginsenoside Rh2-mediated G1 growth arrest and apoptosis in human lung adenocarcinoma A549 cells

Authors: X. Liu, Y. Sun, L. Yue, S. Li, X. Qi, H. Zhao, Y. Yang, C. Zhang and H. Yu

Ginsenoside Rh2 has been shown to have an anti-tumor effect on a wide range of cancers. A previous study has shown that ginsenoside Rh2 can inhibit the proliferation of the human lung adenocarcinoma A549 cell line in a dose-dependent manner byactivating caspase-8/3 activity to promote apoptosis. However, the association of the JNK signaling pathways and t.. Read More»

Genet. Mol. Res. 15(3):
gmr.15039003
DOI:
10.4238/gmr.15039003

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