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Selection

Human Genetics   Research Article

Genetic algorithm-based efficient feature selection for classification of pre-miRNAs

Authors: P. Xuan, M.Z. Guo, J. Wang, C.Y. Wang, X.Y. Liu and Y. Liu

In order to classify the real/pseudo human precursor microRNA (pre-miRNAs) hairpins with ab initio methods, numerous features are extracted from the primary sequence and second structure of pre-miRNAs. However, they include some redundant and useless features. It is essential to select the most representative feature subset; t.. Read More»

Genet. Mol. Res. 10(2):
vol10-2gmr969
DOI:
10.4238/vol10-2gmr969
Plant Genetics   Research Article

Estimation of genetic parameters and selection of high-yielding, upright common bean lines with slow seed-coat darkening

Authors: R.C. Alvares, F.C. Silva, L.C. Melo, P.G.S. Melo and H.S. Pereira

Slow seed coat darkening is desirable in common bean cultivars and genetic parameters are important to define breeding strategies. The aims of this study were to estimate genetic parameters for plant architecture, grain yield, grain size, and seed-coat darkening in common bean; identify any genetic association among these trai.. Read More»

Genet. Mol. Res. 15(4):
gmr15049081
DOI:
10.4238/gmr15049081
Medical Genetics   Research Article

Locally linear embedding and neighborhood rough set-based gene selection for gene expression data classification

Authors: L. Sun, J.-C. Xu, W. Wang and Y. Yin

Cancer subtype recognition and feature selection are important problems in the diagnosis and treatment of tumors. Here, we propose a novel gene selection approach applied to gene expression data classification. First, two classical feature reduction methods including locally linear embedding (LLE) and rough set (RS) are summar.. Read More»

Genet. Mol. Res. 15(3):
gmr.15038990
DOI:
10.4238/gmr.15038990
Plant Genetics   Research Article

Genetic parameters and prediction of genotypic values for root quality traits in cassava using REML/BLUP

Authors: E.J. Oliveira, F.A. Santana, L.A. Oliveira and V.S. Santos

The aim of this study was to estimate the genetic parameters and predict the genotypic values of root quality traits in cassava (Manihot esculenta Crantz) using restricted maximum likelihood (REML) and best linear unbiased prediction (BLUP). A total of 471 cassava accessions were evaluated over two years of cultivatio.. Read More»

Genet. Mol. Res. 13(3):
2014.August.28.13
DOI:
10.4238/2014.August.28.13
Animal Genetics   Research Article

MRJP microsatellite markers in Africanized Apis mellifera colonies selected on the basis of royal jelly production

Authors: R.S. Parpinelli, M.C.C. Ruvolo-Takasusuki and V.A.A. Toledo

It is important to select the best honeybees that produce royal jelly to identify important molecular markers, such as major royal jelly proteins (MRJPs), and hence contribute to the development of new breeding strategies to improve the production of this substance. Therefore, this study focused on evaluating the genetic varia.. Read More»

Genet. Mol. Res. 13(3):
2014.August.28.16
DOI:
10.4238/2014.August.28.16
Animal Genetics   Research Article

Gene regulatory network identification from the yeast cell cycle based on a neuro-fuzzy system

Authors: B.H. Wang, J.W. Lim and J.S. Lim

Many studies exist for reconstructing gene regulatory networks (GRNs). In this paper, we propose a method based on an advanced neuro-fuzzy system, for gene regulatory network reconstruction from microarray time-series data. This approach uses a neural network with a weighted fuzzy function to model the relationships between genes. Fuzzy rules, which deter.. Read More»

Genet. Mol. Res. 15(3):
gmr.15039002
DOI:
10.4238/gmr.15039002
Cytogenomics   Research Article

Genomic selection of seed weight based on low-density SCAR markers in soybean

Authors: Y.J. Shu, D.S. Yu, D. Wang, X. Bai, Y.M. Zhu and C.H. Guo

With the development of molecular marker technology, crop breeding has been accelerated by marker-assisted selection for the improvement of quantitative traits. However, due to the traits’ polygenic nature, traditional marker-assisted selection methods are ill-suited for identification of quantitative trait loci. Genomic selection (GS) was introduce.. Read More»

Genet. Mol. Res. 12(3):
2013.July.3.2
DOI:
10.4238/2013.July.3.2
Plant Genetics   Research Article

Proposal of a super trait for the optimum selection of popcorn progenies based on path analysis

Authors: A.T. do Amaral J�ºnior, A. dos Santos, I.F.S. Gerhardt, R.N.F. Kurosawa, N.F. Moreira, M.G. Pereira, G. de A. Gravina and F.H. de L. Silva

A challenge faced by popcorn breeding programs is the existence of a negative correlation between the two main traits, popping expansion and yield, which hinders simultaneous gains. The objective of this study was to investigate the use of a new variable or super trait, which favors the reliable selection of superior progenies.. Read More»

Genet. Mol. Res. 15(4):
gmr15049309
DOI:
10.4238/gmr15049309
Bioinformatics   Research Article

Use of microsatellite markers in molecular analysis of segregating populations of papaya (Carica papaya L.) derived from backcrossing

Authors: F.O. Pinto, M.G. Pereira, L.N. Luz, D.L. Cardozo, H.C.C. Ramos and C.M.P. Macedo

Brazil is the world leader in papaya production. However, only a small number of cultivars are registered for commercial planting, mainly owing to delays in obtaining cultivars and the high costs of the field phase of breeding programs. These costs can be reduced when molecular tools are combined with conventional breeding methods. In the present study, w.. Read More»

Genet. Mol. Res. 12(3):
2013.July.8.6
DOI:
10.4238/2013.July.8.6
Animal Genetics   Research Article

Differential expression of Toll-like receptors in goat dominant and nondominant follicles

Authors: G.X. E, Y.J. Zhao, Y.H. Ma, M.X. Chu, Q.H. Hong, S.J. Lv, L. Zhu, F.K. Li, Y.G. Han, X. Wu5and Y.F. Huang

The mechanism of dominant follicle selection is unclear because of its physiological complexity. However, some studies have reported that the immune system plays an important role in reproductive physiology. The objective of the current study was to investigate the differential expression of Toll-like receptors (TLRs) in the d.. Read More»

Genet. Mol. Res. 15(4):
gmr15049157
DOI:
10.4238/gmr15049157