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Sting_rdb: a relational database of structural parameters for protein analysis with support for data warehousing and data mining
Authors: Oliveira SRM, Almeida GV, Souza KRR, Rodrigues DN, Kuser-Falcao PR, Yamagishi MEB, Santos EH, Vieira FD, Jardine JG and Neshich G
An effective strategy for managing protein databases is to provide mechanisms to transform raw data into consistent, accurate and reliable information. Such mechanisms will greatly reduce operational inefficiencies and improve one’s ability to better handle scientific objectives and interpret the research results. To ach.. Read More»
- Genet. Mol. Res. 6(4):
Expression divergence of FRUITFULL homeologs enhanced pod shatter resistance in Brassica napus
Authors: P.F. Peng, Y.C. Li, D.S. Mei, J. Colasanti, L. Fu, J. Liu, Y.F. Chen and Q. Hu
To improve pod shatter resistance in the important oilseed crop Brassica napus, the phenotypic diversity of B. napus was tested using 80 B. napus varieties for pod shatter resistance by a random impact test. Among these varieties, R1-1 was identified as resistant, while R2, 8908B was susceptible to shatter. To understand the molecular basis for this pheno.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.February.2.11
- DOI:
- 10.4238/2015.February.2.11
Proteomic changes in maize as a response to heavy metal (lead) stress revealed by iTRAQ quantitative proteomics
Authors: G.K. Li1,3*, J. Gao4*, H. Peng1,2, Y.O. Shen1, H.P. Ding1, Z.M. Zhang1, G.T. Pan1 and H.J. Lin1
Lead (Pb), a heavy metal, has become a crucial pollutant in soil and water, causing not only permanent and irreversible health problems, but also substantial reduction in crop yields. In this study, we conducted proteome analysis of the roots of the non-hyperaccumulator inbred maize line 9782 at four developmental stages (0, 12, 24, and 48 h) under Pb pol.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017254
- DOI:
- 10.4238/gmr.15017254
Development of polymorphic SSR markers in the razor clam (Sinonovacula constricta) and cross-species amplification
Authors: Y.H. Dong1, H.H. Yao1, C.S. Sun2, D.M. Lv1, M.Q. Li1 and Z.H. Lin1
Next-generation sequencing provides large-scale sequencing data with relative ease and at a reasonable cost, making it possible to identify a large amount of SSR markers in a timely and cost-effective manner. On the basis of the transcriptome database of Sinonovacula constricta obtained by Illumina/Solexa pyrosequencing, 60 polymorphic SSR markers were de.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017285
- DOI:
- 10.4238/gmr.15017285
Application of MUTIC to the exploration of gene expression data in prostate cancer
Authors: Goertzel B, Pennachin C, Coelho LS and Mudado MA
We show here an example of the application of a novel method, MUTIC (model utilization-based clustering), used for identifying complex interactions between genes or gene categories based on gene expression data. The method deals with binary categorical data which consist of a set of gene expression profiles divided into two bi.. Read More»
- Genet. Mol. Res. 6(4):
Infection of Plasmodiophora brassicae in Chinese cabbage
Authors: R. Ji*, L. Zhao*, M. Xing, X. Shen, Q. Bi, S. Peng and H. Feng
Brassica crops infected by Plasmodiophora brassicae can produce root galls (clubroots) and be prevented from growing normally. To understand the series of changes that occur in the host root during root gall production, the resistance character of 21 Chinese cabbage lines were identified and then resistant and susceptible lines were used for infection obs.. Read More»
- Genet. Mol. Res. 13(4):
- 2014
- DOI:
- 10.4238/2014
Comparison of methods used to identify superior individuals in genomic selection in plant breeding
Authors: L.L. Bhering, V.S. Junqueira, L.A. Peixoto, C.D. Cruz and B.G. Laviola
The aim of this study was to evaluate different methods used in genomic selection, and to verify those that select a higher proportion of individuals with superior genotypes. Thus, F2 populations of different sizes were simulated (100, 200, 500, and 1000 individuals) with 10 replications each. These consisted of 10 linkage groups (LG) of 100 cM each, cont.. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.9.26
- DOI:
- http://dx.doi.org/10.4238/2015.September.9.26
Vascular endothelial growth factor as an angiogenesis biomarker for the progression of autosomal dominant polycystic kidney disease
Authors: D.P. Martins1, M.A. Souza1, M.E. Lopes Baitello1, V. Nogueira1, C.I. Ferreira Oliveira1, M.A. de Souza Pinhel1, H.C. Caldas2, M.A. Filho2 and D.R. Silva Souza1
Autosomal dominant polycystic kidney disease (ADPKD) is a hereditary nephropathy characterized by abnormal growth of epithelial cells. Genetic factors, including the vascular endothelial growth factor (VEGF) gene, play an important role in its progression. The main aim of this study was to evaluate the influence of VEGF-C936T polymorphism in the developme.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017623
- DOI:
- 10.4238/gmr.15017623
Clinical characteristics of men with non-mosaic Klinefelter syndrome in northeastern China: implications for genetic counseling
Authors: M. Zhang, H.-T. Fan, H.-S. Zheng, Q.-S. Zhang, S.-Q. Feng and R.-W. Li
Klinefelter syndrome (KS) is the most common genetic cause of male infertility. Widespread development in assisted reproductive technology has provided non-mosaic KS patients with the opportunity of having biological children. Testosterone replacement therapy and micro-dissection testicular sperm extraction are effective sperm retrieval techniques for KS .. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.9.27
- DOI:
- http://dx.doi.org/10.4238/2015.September.9.27
Optimization of dengue virus genome assembling using GSFLX 454 pyrosequencing data: evaluation of assembling strategies
Authors: S.M.M. Casseb J.F. Cardoso R. Ramos A. Carneiro M. Nunes P.F.C. Vasconcelos A. Silva
Currently assembling genomes without reference is one of the most important challenges for bioinformaticists all over the world in an attempt to characterize new organisms. The current study has used two dengue virus type 4 (DENV-4) strains recently isolated in Brazil, which have its genomes sequenced using the GSFLX 454 seque.. Read More»
- Genet. Mol. Res. 11(4):
- 2012.August.17.6
- DOI:
- 10.4238/2012.August.17.6