Se
Distribution of Candida albicans in the oral cavity of children aged 3-5 years of Uygur and Han nationality and their genotype in caries-active groups
Authors: N. Wu, J. Lin, L. Wu and J. Zhao
We analyzed the distribution of Candida albicans in the oral cavity of 3-5-year-old children of Uygur and Han nationalities as well as their genotypes in caries-active groups in the Urumqi municipality. CHROMagar Candida was separately cultivated, and we identified 359 Uygur and Han children aged 3-5 years. We randomly selected 20 Han children and 20 Uygur c.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.January.30.18
- DOI:
- 10.4238/2015.January.30.18
Isolation of new polymorphic microsatellite markers from the marbled rockfish Sebastiscus marmoratus
Authors: H.W. Deng, Z.B. Li, G. Dai, Y. Yuan, Y.F. Ning, J.B. Shangguan and Y.S. Huang
The marbled rockfish, Sebastiscus marmoratus, is an important commercially near-shore fish that inhabits the beach rocky bottom from Japan to the South China Sea. Eleven polymorphic microsatellite loci were developed from S. marmoratus and were used to identify polymorphisms in 30 samples from a wild population. The allele locus number ranged from 2 to 7. Po.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.January.30.19
- DOI:
- 10.4238/2015.January.30.19
Cloning and expression analysis of cysteine protease gene (MwCP) in Agropyron mongolicum Keng
Authors: T.G.B.Y. Ao1,3, M.L. Lang2, Y.Q. Li3, Y. Zhao1, L.C. Wang1 and X.J. Yang1,2,4
In this study, a cysteine protease gene (MwCP) from Agropyron mongolicum Keng was isolated using RACE. Sequence analysis indicated that MwCP was 1473 bp, and it contained a 1134-bp open reading frame, which encoded 377 amino acids with a 24-amino acid N-terminal signal peptide. The results indicated that the MwCP protein was a new member of the papain C1A.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017424
- DOI:
- 10.4238/gmr.15017424
Structural chromosomal abnormalities in couples in cases of recurrent spontaneous abortions in Jilin Province, China
Authors: H.-T. Fan, M. Zhang, P. Zhan, X. Yang, W.-J. Tian and R.-W. Li
Recurrent spontaneous abortions (RSAs) occur in approximately 15 to 20% of all clinically recognizable pregnancies. Structural chromosome abnormalities result in increased risk of pregnancy loss. Parental chromosomal abnormalities are an important genetic cause of RSAs. Some cytogenetic investigations have been performed in various countries and regions t.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017443
- DOI:
- 10.4238/gmr.15017443
Association of interleukin-1�² -511C/T promoter polymorphism with COPD risk: a meta-analysis
Authors: Y.S. Wang, L. Liu, X.Y. Xu, J.L. Wang, H. Zhou, T.L. Li and Z.A. Liang
Studies examining the role of interleukin (IL)-1β -511C/ T promoter polymorphism in the pathogenesis of chronic obstructive pulmonary disease (COPD) have shown inconsistent results. This metaanalysis was performed to assess the association between the IL-1β -511C/T promoter polymorphism and COPD susceptibility. Published case-control, cross-sect.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.4.5
- DOI:
- 10.4238/2015.May.4.5
�²-asarone from Acorus gramineus alleviates depression by modulating MKP-1
Authors: Y.R. Sun, X.Y. Wang, S.S. Li, H.Y. Dong and X.J. Zhang
In this study, we investigated the antidepressant effects of hippocampal neuron administration of β-asarone, a selective mitogen-activated protein kinase phosphatase-1 inhibitor, in a rat model of depression. Our previous studies showed that the extracellular signal-regulated kinase signaling pathway and brain-derived neurotrophic factor expression, .. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.4.7
- DOI:
- 10.4238/2015.May.4.7
A novel mutation links to von Hippel-Lindau syndrome in a Chinese family with hemangioblastoma
Authors: X.M. Fu, S.L. Zhao, J.C. Gui, Y.Q. Jiang, M.N. Shen, D.L. Su, B.J. Gu,X.Q. Wang, Q.J. Ren, X.D. Yin, W.B. Huang and X.G. Chen
Hemangioblastoma of the central nervous system occurs as sporadic tumors or as a part of von Hippel-Lindau (VHL) disease, an autosomal dominant hereditary tumor syndrome caused by a germline mutation in the VHL tumor suppressor gene. We screened a Chinese family with VHL for mutations in the VHL gene and evaluated a genetic test for diagnosing VHL disease.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.4.9
- DOI:
- 10.4238/2015.May.4.9
Expression of high-mobility group box protein 1 in diabetic foot atherogenesis
Authors: C.F. Tsao, W.T. Huang, T.T. Liu, P.W. Wang, C.W. Liou, T.K. Lin,C.J. Hsieh and S.W. Weng
The role of high mobility group box 1 (HMGB1) has been demonstrated in stroke and coronary artery disease but not in peripheral arterial occlusive disease (PAOD). The pathogenesis of HMGB1 in acute and chronic vascular injury is also not well understood. We hypothesized that HMGB1 induces inflammatory markers in diabetic PAOD patients. We studied 36 diabe.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.4.10
- DOI:
- 10.4238/2015.May.4.10
Cumulative methylation alternations of gene promoters and protein markers for diagnosis of epithelial ovarian cancer
Authors: B.L. Xing, T. Li, Z.H. Tang, L. Jiao, S.M. Ge, X. Qiang and J. OuYang
DNA methylation plays an important role in carcinogenesis and cancer development. In this study, we examined gene methylation in epithelial ovarian cancer (EOC) using cationic conjugated polymer (CCP)-based fluorescence resonance energy transfer (FRET) to evaluate the application of cumulative methylation alternations of genes associated with cancer antig.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.4.11
- DOI:
- 10.4238/2015.May.4.11
Matrix metalloproteinase variants associated with risk and clinical outcome of esophageal cancer
Authors: L. Zhang, R.-X. Xi and X.-Z. Zhang
We conducted a case-control study to investigate the role of matrix metalloproteinase (MMP) 2, MMP3, and MMP9 single nucleotide polymorphisms on susceptibility to esophageal squamous cell carcinoma (ESCC) in a Chinese population, and their association with environmental factors. A total of 226 patients with ESCC, and 226 age- and gender-matched healthy co.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.4.20
- DOI:
- 10.4238/2015.May.4.20