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Human Genetics   Research Article

Survey of attitude and knowledge of reproductive health among middle school students in Luoyang, China

Authors: P. Wang, Y.J. Zhang, X.J. Pan, X.Y. Xia and S.Y. Lv

The aim of this study was to assess the knowledge and attitude of AIDS and sexual behavior of middle school students. Structural questionnaires were designed to interview 1980 junior and senior middle school students about their basic knowledge, attitude, and behavior with respect to AIDS and sexual behavior. Students were rec.. Read More»

Genet. Mol. Res. 13(3):
2014.March.24.17
DOI:
10.4238/2014.March.24.17
Animal Genetics   Research Article

Mutation analysis of a Chinese pedigree with triphalangeal thumb-polysyndactyly syndrome

Authors: X.S. Xing, H.W. Zhu, C. Chen, S.S. Wang, Y. Luo and X. Zhang

Triphalangeal thumb-polysyndactyly syndrome (TPTPS) is an autosomal dominant limb disorder with triphalangeal thumbs, polysyndactyly, and syndactyly. In this study, we describe a four-generation Han Chinese family with eight affected members. Haplotype analysis, Affymetrix SNP 6.0 arrays, qPCR, and gap-PCR were performed. Hapl.. Read More»

Genet. Mol. Res. 13(1):
2014.January.17.8
DOI:
10.4238/2014.January.17.8
Human Genetics   Research Article

Prospective study of MTHFR genetic polymorphisms as a possible etiology of male infertility

Authors: S.-S. Li, J. Li, Z. Xiao, A.-G. Ren and L. Jin

The aim of this study was to explore the relationship between 2 genetic polymorphisms of the methylenetetrahydrofolate reductase gene (MTHFR), C677T and A1298C, and determine the long-term reproductive outcome in infertile men. This was a prospective study conducted in an andrology clinic. Men with a 1-year history of.. Read More»

Genet. Mol. Res. 13(3):
2014.March.24.26
DOI:
10.4238/2014.March.24.26
Animal Genetics   Research Article

Polymorphism of the inhibin �²A gene and its relationship with superovulation traits in Chinese Holstein cows

Authors: W.C. Yang, S.J. Li, L. Chen and L.G. Yang

Inhibin is a major regulator of secretion of follicle-stimulating hormone, which is involved in follicular development and regulation of steroidogenesis in females. The objectives of this study were to detect polymorphisms of the bovine inhibin beta-A subunit (INHβA) gene and to evaluate its associations with superovulato.. Read More»

Genet. Mol. Res. 13(1):
2014.January.17.11
DOI:
10.4238/2014.January.17.11
Animal Genetics   Research Article

Development and characterization of novel SSR markers in Siniperca kneri Garman

Authors: M. Yang, H.Z. Zheng, X.-F. Liang, C.X. Tian, Y.Q. Dou, K.C. Zhu and Y.C. Yuan

In this study, 37 transcriptome-derived simple sequence repeat (SSR) markers and 18 genomic SSR markers were developed and characterized in the Chinese perch, Siniperca kneri Garman. The average allele number per locus was 5.1 (range: 2-8) for transcriptome-derived SSRs and 3.8 (range: 2-5) for genomic SSRs. The avera.. Read More»

Genet. Mol. Res. 13(3):
2014.March.24.18
DOI:
10.4238/2014.March.24.18
Plant Genetics   Research Article

Microsatellite markers for the Cabre�ºva tree, Myroxylon peruiferum (Fabaceae), an endangered medicinal species from the Brazilian Atlantic Forest

Authors: K.D. Schwarcz, M.M. Bajay, C.M.T. Macrini, V.L.P. Salazar, A.P. Souza, J.B. Pinheiro, P.H.S. Brancalion, R.R. Rodrigues and M.I. Zucchi

The Cabreúva tree, Myroxylon peruiferum, is an endangered tropical species from Brazil used in forest restoration projects. It is known for its medicinal properties. Eleven microsatellite markers were developed for this species, from a microsatellite-enriched library. Nine of these markers, characterized in 30 .. Read More»

Genet. Mol. Res. 13(3):
2014.March.26.1
DOI:
10.4238/2014.March.26.1
Medical Genetics   Research Article

RNA-seq reveals the downregulated proteins related to photosynthesis in growth-inhibited rice seedlings induced by low-energy N+ beam implantation

Authors: Q.F. Chen, H.Y. Ya, W.D. Wang and Z. Jiao

Transcriptomic research based on RNA sequencing (RNA-seq) technology is innovative and will provide new opportunities and biological perspectives for the use of ion-beam implantation in plants. Using RNA-seq, transcriptomes of whole rice seedlings generated from seeds implanted with a low-energy N+ beam were analyzed 96 h afte.. Read More»

Genet. Mol. Res. 13(3):
2014.March.26.9
DOI:
10.4238/2014.March.26.9
Human Genetics   Research Article

Repair of cartilage defects in BMSCs via CDMP1 gene transfection

Authors: G. Wu, Y. Cui, Y.T. Wang, M. Yao, J. Hu, J.X. Li, Y. Wang andB. Zhang

This study aimed at investigating the ability of cartilage-derived morphogenetic protein 1 (CDMP1) gene-transfected bone marrow mesenchymal stem cells (BMSCs) loaded on the poly(lactic-co-glycolic acid) (PLGA) scaffold for the repair of laryngeal cartilage defects and make a preliminary assessment of its repair effect. The mRN.. Read More»

Genet. Mol. Res. 13(1):
2014.January.17.14
DOI:
10.4238/2014.January.17.14
Plant Genetics   Research Article

Morphology and photosynthetic enzyme activity of maize phosphoenolpyruvate carboxylase transgenic rice

Authors: W.C.Li, J. Wang, Y.L. Sun, S.D. Ji, S.W. Guo

The morphology and photosynthetic enzyme activity were studied in maize phosphoenolpyruvate carboxylase transgenic rice and non-transgenic rice. The results showed that compared with non-transgenic rice, phosphoenolpyruvate carboxylase transgenic rice was taller and had a stronger stalk, wider leaves, and more exuberant root s.. Read More»

Genet. Mol. Res. 14(4):
2015.December.1.8
DOI:
10.4238/2015.December.1.8
Medical Genetics   Research Article

Prospective analysis of KRAS wild-type patients with metastatic colorectal cancer using cetuximab plus FOLFIRI or FOLFOX4 treatment regimens

Authors: M.Y. Huang, M.J. Chen, H.L. Tsai, C.H. Kuo, C.J. Ma, M.F. Hou, S.C. Chuang, S.R. Lin and J.Y. Wang

Cetuximab, a monoclonal antibody targeting epidermal growth factor receptor, has proven to be efficient in the treatment of metastatic colorectal cancer. We made a prospective study of the efficacy and toxicities of cetuximab-combination first-line (FOLFOX4) versus second/third-line (FOLFIRI) chemotherapy in 98 KRAS wildtype p.. Read More»

Genet. Mol. Res. 10(4):
2011.October.3.4
DOI:
10.4238/2011.October.3.4