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Development of EST-SSR markers related to disease resistance and their application in genetic diversity and evolution analysis in Gossypium
Authors: B.H. Wang, P. Rong, X.X. Cai, W. Wang, X.Y. Zhu, C.J. Chen, Y.Y. Xu, X.J. Huang, Z.M. Zhuang and C.B. Wang
Cotton (Gossypium spp) is one of the most economically important crops that provide the world’s most widely used natural fiber. Diseases such as Fusarium wilt and particularly Verticillium wilt seriously affect cotton production, and thus breeding for disease resistance is one of the most important goals of cotton breeding programs. Currently, poten.. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.9.4
- DOI:
- http://dx.doi.org/10.4238/2015.September.9.4
Polymorphic microsatellite markers in the false kelpfish Sebastiscus marmoratus: isolation, characterization, and cross-species amplification
Authors: H.B. Liu, S.F. Liu, J.B. Ye, Y.J. Yuan, S.X. Dingand Z.M. Zhuang
A (GT/CA)13-microsatellite-enriched genomic library of the false kelpfish Sebastiscus marmoratus was constructed, and 20 polymorphic microsatellite loci were isolated and characterized. The polymorphisms were investigated in 48 wild individuals from a single population collected from the northern Yellow Sea. The numbers of all.. Read More»
- Genet. Mol. Res. 13(1):
- 2014.January.10.4
- DOI:
- 10.4238/2014.January.10.4
cDNA-AFLP transcriptional profiling reveals genes expressed during flower development in Oncidium Milliongolds
Authors: X. Qian, M.J. Gong*, C.X. Wang and M. Tian
The flower developmental process, which is crucial to the whole lifecycle of higher plants, is influenced by both environmental and endogenous factors. The genus Oncidium is commercially important for cut flower and houseplant industry and is ideal for flower development studies. Using cDNA-amplified restriction fragm.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.February.21.5
- DOI:
- 10.4238/2014.February.21.5
A985G mutation incidence in the medium-chain acyl-CoA dehydrogenase (MCAD) gene in Brazil
Authors: A.C.S. Ferreira, M.P.A. Orlandi, V.C. Oliveira, F.S.V. Malta,F.A. Caxito, K.B. Gomes, E.R. Valadares and A.L.B. Godard
In view of the serious consequences of medium-chain acyl-CoA dehydrogenase (MCAD) deficiency and the absence of information about its incidence in the Brazilian population, we examined the frequency of the A985G mutation in the MCAD gene. A retrospective analysis was made of data on 1722 individuals (844 females) genotyped for.. Read More»
- Genet. Mol. Res. 8(2):
- vol8-2gmr579
- DOI:
- 10.4238/vol8-2gmr579
Prevalence of human papillomavirus, Chlamydia trachomatis, and Trichomonas vaginalis infections in Amazonian women with normal and abnormal cytology
Authors: E. Costa-Lira, A.H.V.L. Jacinto, L.M. Silva, P.F.R. Napole�£o,R.A.A. Barbosa-Filho, G.J.S. Cruz, S. Astolfi-Filho and C.M. Borborema-Santos
Sexually transmitted infections are an important cause of morbidity among sexually active women worldwide, and have been implicated as cofactors in the pathogenesis of cervical cancer. We investigated the prevalence of human papillomavirus (HPV), Chlamydia trachomatis (CT), and Trichomonas vaginalis (TV), and accessed the dive.. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029626
- DOI:
- 10.4238/gmr16029626
Biochip analysis of prostate cancer
Authors: M.Q. Fan, P.X. Wang, J.Y. Feng, Y. Xiao and C.B. Huang
Microarray expression analysis was used to forecast the roles of differentially co-expressed genes (DCG) and DCG and links in the pathogenesis of prostate cancer. In addition, we demonstrate that the relationship between transcriptional factors (TFs) and their targets can be considered a key factor in determining the differenc.. Read More»
- Genet. Mol. Res. 13(1):
- 2014.January.10.6
- DOI:
- 10.4238/2014.January.10.6
Treatment of silicosis with hepatocyte growth factor-modified autologous bone marrow stromal cells: a non-randomized study with follow-up
Authors: W.W. Liu, H.X. Wang, W. Yu, X.Y. Bi, J.Y. Chen, L.Z. Chen, L. Ding, D.M. Han, Z.K. Guo and Y.X. Lei
Pulmonary silicosis is an irreversible and untreatable disease that is characterized by interstitial lesions and perpetual fibrosis in the lungs. This study was performed to determine whether mesenchymal stem cells (MSCs) and hepatocyte growth factor (HGF) could exhibit therapeutic effects on human silicosis. This non-randomized uncontrolled trial compris.. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.9.7
- DOI:
- http://dx.doi.org/10.4238/2015.September.9.7
Marker-assisted selection of Fusarium wilt-resistant and gynoecious melon (Cucumis melo L.)
Authors: P. Gao, S. Liu, Q.L. Zhu and F.S. Luan
In this study, molecular markers were designed based on the sex determination genes ACS7 (A) and WIP1 (G) and the domain in the Fusarium oxysporum-resistant gene Fom-2 (F) in order to achieve selection of F. oxysporum-resistant gynoecious melon plants. Markers of A and F are cleaved amplified polymorphic sequences that distinguish alleles according to res.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.8.16
- DOI:
- 10.4238/2015.December.8.16
Screening of mutations in the GCK gene in Jordanian maturity-onset diabetes of the young type 2 (MODY2) patients
Authors: R. Khalil, F. Al-Sheyab, E. Khamaiseh, M.A. Halaweh andH.A. Abder-Rahman
Maturity-onset diabetes of the young type 2 (MODY2) is a genetic form of diabetes mellitus caused by mutations in the glucokinase gene (GCK). We assessed the frequency of GCK gene mutations in Jordanian suspected MODY2 patients. We screened exons 7, 8 and 9, which are specific for pancreatic glucokinase, for mutations at posit.. Read More»
- Genet. Mol. Res. 8(2):
- vol8-2gmr597
- DOI:
- 10.4238/vol8-2gmr597
Discovery and characterization of new microsatellite loci in Dipteryx alata Vogel (Fabaceae) using next-generation sequencing data
Authors: R.A. Guimar�£es, M.P.C. Telles, A.M. Antunes, K.M. Corr�ªa,C.V.G. Ribeiro, A.S.G. Coelho and T.N. Soares
The use of next-generation sequencing (NGS) technologies provides a great volume of genome sequence data even for non-model species. The development of microsatellite markers using these data is a relatively quick and easy process. Dipteryx alata Vogel (Fabaceae) is an arboreal species from the Cerrado biome and is considered .. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029639
- DOI:
- 10.4238/gmr16029639