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Next-generation sequencing analysis of the ARMS2 gene in Turkish exudative age-related macular degeneration patients
Authors: H. Bardak, M. Gunay, Y. Ercalik, Y. Bardak, H. Ozbas and O. Bagci
Age-related macular degeneration (AMD) is the leading cause of blindness in developed countries. It is a complex disease with both genetic and environmental risk factors. To improve clinical management of this condition, it is important to develop risk assessment and prevention strategies for environmental influences, and esta.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019135
- DOI:
- 10.4238/gmr16019135
Expression of prion protein in the cerebrospinal fluid of patients with Parkinson�s disease complicated with rapid eye movement sleep behavior disorder
Authors: W.J. Zhang, X.L. Shang, J. Peng, M.H. Zhou and W.J. Sun
Parkinson’s disease (PD) is one of the most common neurodegenerative diseases and mainly manifests with decreasing numbers of dopaminergic neurons. Rapid eye movement (REM) sleep behavior disorder (RBD) has an incidence of 15-47% in all PD patients. Prion proteins (PrPs), which are expressed in both neurons and glial cel.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019022
- DOI:
- 10.4238/gmr16019022
Phenotypic and molecular characterization of a tomato (Solanum lycopersicum L.) F2 population segregation for improving shelf life
Authors: K.N. Yogendra P.H. Ramanjini Gowda
Breeding for better quality fruits is a major focus for tomatoes, which are continuously subjected to post-harvest losses. Several methods have been used to improve the fruit shelf life of tomatoes, including the use of ripening gene mutants of Solanum lycopersicum. We developed extended shelf-life tomato hybrids with better quality fruits using ripening .. Read More»
- Genet. Mol. Res. 12(1):
- 2013.January.9.4
- DOI:
- 10.4238/2013.January.9.4
Identification of polymorphisms and transcriptional activity of the proto-oncogene KIT located on both autosomal and B chromosomes of the Chinese raccoon dog
Authors: Y.M. Li1, Y. Zhang1, W.J. Zhu1, S.Q. Yan1 and J.H. Sun2
B chromosomes are dispensable and co-exist with autosomal and sex chromosomes. The karyotype of the Chinese raccoon dog (Nyctereutes procyonoides procyonoides) comprises 0-4 B chromosomes. The proto-oncogene KIT is found on all B chromosomes of the Chinese raccoon dog. In the present study, partial DNA and mRNA sequences of KIT were amplified and sequence.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017398
- DOI:
- 10.4238/gmr.15017398
Characterization of the resistance gradient of cacao genotypes (F2 Sca6 x ICS1) to black pod disease using phytopathometric, genetic and molecular approaches
Authors: E.S.L. Santos
-.. Read More»
- Genet. Mol. Res. 8(4):
- vol8-4ta023
- DOI:
- 10.4238/vol8-4ta023
Mitochondrial DNA insertions in the nuclear Capra hircus genome
Authors: F.Y. Ning, J. Fu and Z.H. Du
Nuclear mitochondrial pseudogenes (numts), originating from mtDNA insertions into the nuclear genome, have been detected in many species. However, the distribution of numts in the newly published nuclear genome of domestic goat (Capra hircus) has not yet been explored. We used the entire goat mtDNA sequence and nuclear genome,.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16018266
- DOI:
- 10.4238/gmr16018266
Antisense expression of Gossypium hirsutum UDP-glucuronate decarboxylase in Arabidopsis leads to changes in cell wall components
Authors: D.M. Zhang1*, Y.X. Pan2*, Y. Zhang1, Z.K. Li1, L.Q. Wu1, H.W. Liu1, G.Y. Zhang1, X.F. Wang1 and Z.Y. Ma1
UDP-glucuronate decarboxylase (UDP-xylose synthase; UXS, EC 4.1.1.35) is an essential enzyme of the non-cellulosic polysaccharide biosynthetic pathway. In the present study, using transient expression of fluorescently labeled Gossypium hirsutum UXS (GhUXS3) protein in onion epidermal cells, we observed that this protein was distributed in the cytoplasm. T.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017409
- DOI:
- 10.4238/gmr.15017409
A genome-wide association study of growth trait-related single nucleotide polymorphisms in Chinese Yancheng chickens
Authors: C.F. Jin, Y.J. Chen, Z.Q. Yang, K. Shi, C.K. Chen
Chicken (Gallus gallus) growth traits are important economic traits, and many studies have been conducted on genetic selection for body weight. However, most of these studies have detected functional chromosome mutations or regions by conventional molecular markers or gene chips. In this study, we performed a new genome-wide a.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.1.30
- DOI:
- 10.4238/2015.December.1.30
Genetic diversity and mating system of Copaifera langsdorffii (Leguminosae/Caesalpinioideae)
Authors: A. Gonela A.M. Sebbenn H.H. Soriani M.A. Mestriner C.A. Martinez A.L. Alzate-Marin
Copaifera langsdorffii, locally known as copaÃ?Âba, is a valuable tropical tree with medicinal properties of its oil. We studied the genetic variation, genetic structure, and the mating system of trees in stands of C. langsdorffii (Leguminosae/Caesalpinioideae) located in an extensive area between the Pardo and Mogi-GuaÃ?§u basins in SÃ?£o Paulo State, Br.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.February.27.6
- DOI:
- 10.4238/2013.February.27.6
Correlation-based linear discriminant classification for gene expression data
Authors: M. Pan and J. Zhang
Microarray gene expression technology provides a systematic approach to patient classification. However, microarray data pose a great computational challenge owing to their large dimensionality, small sample sizes, and potential correlations among genes. A recent study has shown that gene-gene correlations have a positive effe.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019357
- DOI:
- 10.4238/gmr16019357