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Development and characterization of microsatellite markers for Solen grandis using Illumina sequencing approach
Authors: Y.W. Feng, H.L. Jiang, Y.T. Liu, X.P. Wu, X.Q. Liu and X.M. Wei
Solen grandis is an important economic and overexploited bivalve species. In order to perform its fine-scale genetic analyses, 105 pairs of microsatellites with polymorphism were identified through Illumina Hiseq platform and bioinformatic assembly technology in this study. The estimated fragment size ranged from 100 to 268 bp.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019621
- DOI:
- 10.4238/gmr16019621
Case of escape in cassava, Manihot esculenta Crantz
Authors: N.M.A. Nassar and M. Mendonza
Two cassava escapes where collected from cultivated fields near natural habitat in Bolivia. They are described morphologically and analyzed cytogenetically in this study. It is suggested that they are the product of backcrosses of cassava interspecific hybrids with the cultigen itself, and that selective conditions have develo.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019577
- DOI:
- 10.4238/gmr16019577
Genetic diversity and differentiation in natural populations of Arapaima gigas from lower Amazon revealed by microsatellites
Authors: P.F. Fazzi-Gomes, N. Melo, G. Palheta, S. Guerreiro, M. Amador, A.K. Ribeiro-dos-Santos, S. Santos and I. Hamoy
Genetic variability is one of the important criteria for species conservation decisions. This study aimed to analyze the genetic diversity and the population differentiation of two natural populations of Arapaima gigas, a species with a long history of being commercially exploited. We collected 87 samples of A. gigas from Gran.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019552
- DOI:
- 10.4238/gmr16019552
XRCC1 rs25487 polymorphism is associated with lung cancer risk in epidemiologically susceptible Chinese people
Authors: X. Wang, K.W. Ma, Y.G. Zhao, G.J. Wang, W. Li
Base excision repair (BER) plays an important role in maintaining genome integrity and anti-cancer drug resistance. Single nucleotide polymorphisms (SNPs) in BER genes were detected in 500 lung cancer patients and 500 cancer-free controls. A logistic regression model was applied to analyze the relationship between lung ca.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.1.3
- DOI:
- 10.4238/2015.December.1.3
Structural and functional characterization of the Colletotrichum lindemuthianum nit1 gene, which encodes a nitrate eductase enzyme
Authors: G.B. Nogueira M.V. Queiroz R.A. Ribeiro E.F. Ara�ºjo
Colletotrichum lindemuthianum is the causal agent of plant bean anthracnose, one of the most important diseases affecting the common bean. We investigated the structure and expression of the nit1 gene (nitrate reductase) of C. lindemuthianum. The nit1 gene open reading frame contains 2787 bp, interrupted by a single 69-bp intron. The predicted protein has 90.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.February.8.7
- DOI:
- 10.4238/2013.February.8.7
Genetic tests for low- and middle-income countries: a literature review
Authors: P.E. Maltese, E. Poplavskaia, I. Malyutkina, F. Sirocco, A. Bonizzato, N. Capodicasa, S.Y. Nicoulina, A. Salmina, N. Aksutina, M. Dundar, T. Beccari, S. Cecchin and M. Bertelli
The aim of this review is to describe a series of ten genetic diseases with Mendelian inheritance pattern in people of low- or middle-income countries, which can be easily identified with simple and affordable methods. Recent information shows that although genetic diseases account for more than 10% of infant mortality in such.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019466
- DOI:
- 10.4238/gmr16019466
Evolutionary analysis of the short-type peptidoglycan-recognition protein gene (PGLYRP1) in primates
Authors: W. Liu Y.F. Yao L. Zhou Q.Y. Ni H.L. Xu
Short-type peptidoglycan (PGN)-recognition protein 1 (PGLYRP1), an innate immunity protein that directly breaks down the structure of microbial cell wall PGNs, plays an important role both in antibacterial defenses and several inflammatory diseases. To explore the adaptive evolution of the PGLYRP1 gene in primates and provide insight into the function of thi.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.February.8.10
- DOI:
- 10.4238/2013.February.8.10
Protective effect of p38 MAPK inhibitor on wear debris-induced inflammatory osteolysis through downregulating RANK/RANKL in a mouse model
Authors: D. Chen, Y. Li, F. Guo, Z. Lu, C. Hei, P. Li and Q. Jin
Adult stem cells are known for their plasticity and their potential to differentiate into several different cell types; these characteristics have implications for cell therapy and reproductive biotechnologies. In this study, we report on the isolation and characterization of mesenchymal stem cells (MSC) derived from bovine and buffalo adipose tissue. Cel.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.January.15.6
- DOI:
- 10.4238/2015.January.15.6
Generation of bovine (Bos indicus) and buffalo (Bubalus bubalis) adipose tissue derived stem cells: isolation, characterization, and multipotentiality
Authors: R.V. Sampaio, M.R. Chiaratti, D.C.N. Santos, F.F. Bressan, J.R. Sangalli, A.L.A. S�¡, T.V.G. Silva, N.N. Costa, M.S. Cordeiro, S.S.D. Santos, C.E. Ambrosio, P.R. Adona, F.V. Meirelles, M.S. Miranda and O.M. Ohashi
Previous studies have indicated that the protein tyrosine phosphatase nonreceptor type 22 gene (PTPN22) is associated with type 1 diabetes (T1DM) in the Caucasian population. In the present study, we investigated the relationship between PTPN22 genetic polymorphisms and T1DM in Chinese children. A total of 202 children and adolescents with T1DM and 240 he.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.January.15.7
- DOI:
- 10.4238/2015.January.15.7
Analysis of the cytochrome c oxidase subunit II (COX2) gene in giant panda, Ailuropoda melanoleuca
Authors: S.S. Ling, Y. Zhu, D. Lan, D.S. Li, H.Z. Pang, Y. Wang, D.Y. Li, R.P. Wei, H.M. Zhang, C.D. Wang and Y.D. Hu
The giant panda, Ailuropoda melanoleuca (Ursidae), has a unique bamboo-based diet; however, this low-energy intake has been sufficient to maintain the metabolic processes of this species since the fourth ice age. As mitochondria are the main sites for energy metabolism in animals, the protein-coding genes involved in mitochond.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019158
- DOI:
- 10.4238/gmr16019158