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Human Genetics   Letter to the Editor

Case-control investigations of a DRD2 missense variant in Asian populations: more noise, less signal

Authors: P.G. Sand

--.. Read More»

Genet. Mol. Res. 11(3):
2012.September.25.14
DOI:
10.4238/2012.September.25.14
Human Genetics   Research Article

Lack of an association between TSC gene Arg904Gln polymorphisms and essential hypertension risk based on a meta-analysis

Authors: F. Zhang Y. Yang D. Hu H. Lei Y. Wang

Although there have been several studies investigating a possible association between essential hypertension and TSC gene Arg904Gln polymorphisms, the results have been inconsistent. We conducted a meta-analysis of four case-control studies (one study in Europe and three studies in Asia), including 1811 essential hypertension cases and 1381 controls. The .. Read More»

Genet. Mol. Res. 11(3):
2012.September.26.7
DOI:
10.4238/2012.September.26.7
Plant Genetics   Research Article

Isolation and characterization of 10 microsatellite loci for Pallas� long-tongued bat Glossophaga soricina (Phyllostomidae)

Authors: 3521

Glossophaga soricina is a widespread Neotropical nectarivorous bat. We characterized 10 microsatellite loci isolated from a shotgun genomic library. We analyzed tissues from wing membrane of 67 individuals collected from two populations of Central Brazil (Brasília and Alto Paraíso). The number of alleles per locus ranged from 2 to 20, and th.. Read More»

Genet. Mol. Res. 12(1):
2012.September.26.8
DOI:
10.4238/2012.September.26.8
Human Genetics   Research Article

New insights into telomeric DNA sequence (TTAGGG)n location in bat chromosomes

Authors: K.C. Faria1, S.R.C. Marchesin3, P.R.L. Moreira2, M.R. Beguelini2and E. Morielle-Versute3

Molossidae species, Cynomops abrasus (2n = 34, fun­damental number, FN = 64), Eumops auripendulus (2n = 42, FN = 62), Molossus rufus (2n = 48, FN = 64), Molossops temminckii (2n = 48, FN = 64), and Nyctinomops laticaudatus (2n = 48, FN = 64), and Phyl­lostomidae species, Phyllostomus discolor (2n = 32, FN = 60), have karyotypes with different chro.. Read More»

Genet. Mol. Res. 8(3):
vol8-3gmr637
DOI:
10.4238/vol8-3gmr637
Animal Genetics   Research Article

Investigation of mutations associated with pyrethroid resistance in populations of the New World Screwworm fly, Cochliomyia hominivorax (Diptera: Calliphoridae)

Authors: N.M. da Silva1,2 and A.M.L. de Azeredo-Espin1,2

Cochliomyia hominivorax larvae are known for their parasitic habit in living vertebrates, causing considerable economic losses to livestock industry. This ectoparasite has been controlled mainly by applying insecticides, but this method usually results in the selection of resistant individuals. The resistance mechanism known as knockdown resistance (kdr) .. Read More»

Genet. Mol. Res. 8(3):
vol8-3gmr643
DOI:
10.4238/vol8-3gmr643
Animal Genetics   Research Article

Effect of SERCA2a overexpression in the pericardium mediated by the AAV1 gene transfer on rapid atrial pacing in rabbits

Authors: B.N. Kuken, A.N.W.E. Aikemu, S.Y. Xiang and M.H.Y.T. Wulasihan

To study the effects of overexpression of the sarcoplasmic reticulum ATPase 2a (SERCA2a) gene on the activity and protein expression of SERCA2a after rapid atrial pacing (RAP) in New Zealand white rabbits. New Zealand white rabbits were randomly divided into a sham-operated group (group A), adeno-associated virus 1 (AAV1)/EGFP + atrial fibrillation (AF) m.. Read More»

Genet. Mol. Res. 14(4):
2015.October.28.24
DOI:
10.4238/2015.October.28.24
Bioinformatics   Research Article

Identification of earl millet cultivars using both microsatellites and enzymatic markers

Authors: R.P. Mendon�§a Neto E.V.R. Von Pinho B.L. Carvalho G.S. Pereira

The increasing number of protected and registered cultivars and problems involving seed commercialization make distinction and identification of cultivars imperative. Millet (Pennisetum glaucum), a crop species with protected cultivars in Brazil, has been the target of seed piracy. Thus, with the objective of identifying different lots with regard to origin,.. Read More»

Genet. Mol. Res. 12(1):
2013.January.7.1
DOI:
10.4238/2013.January.7.1
Human Genetics   Research Article

Analysis of vaccine potential of live recombinant and inactivated wild strains of Corynebacterium pseudotuberculosis

Authors: F.A. Dorella

Caseous lymphadenitis (CLA) is a worldwide chronic disease that affects sheep and goats, whose etiological agent is Corynebacterium pseudotuberculosis. Despite all the economic losses caused by CLA, there is not much information about molecular mechanisms in the pathogenesis of this bacterium, and immune prophylaxis against the infection is not able to re.. Read More»

Genet. Mol. Res. 8(3):
vol8-3ta022
DOI:
10.4238/vol8-3ta022
Medical Genetics   Research Article

Relationship between serum leptin levels and non-small cell lung carcinoma: a meta-analysis

Authors: J. Du, J.C. Han, Y.J. Zhang, G.B. Qi, Y. Zhang and H.B. Li

In this study, we analyzed the association between serum leptin levels and non-small cell lung carcinoma (NSCLC). By examining English and Chinese databases, we identified potential relevant studies for statistical analysis. Human-associated case-control studies evaluating the association between serum leptin levels and NSCLC according to the random-effec.. Read More»

Genet. Mol. Res. 14(4):
2015.October.28.32
DOI:
10.4238/2015.October.28.32
Plant Genetics   Research Article

Genes expressed in cotton (Gossypium hirsutum) buds isolated with a subtractive library

Authors: M.P.N. Pinheiro V.G.L. Batista N.F. Martins R.C. Santos P.A. Melo Filho C.R.C. Silva L.M. Lima

A subtractive cDNA library from cotton buds was constructed to prospect for differentially expressed genes related to early bud development. A library was constructed and 768 cDNA sequences were obtained, comprising 168 clusters, with 126 contigs and 42 singlets. Both the Gossypium as well as Arabidopsis databases were utilized for the in silico analysis,.. Read More»

Genet. Mol. Res. 12(1):
2013.January.16.7
DOI:
10.4238/2013.January.16.7