Se
Diversity among isolates of cowpea severe mosaic virus infecting cowpeas in northeastern Brazil
Authors: E.F.M. Abreu M.L.P. Tinoco E.C. Andrade F.J.L. Arag�£o
Eleven isolates of cowpea severe mosaic virus (CPSMV), a member of the genus Comovirus, were selected from 50 samples collected of nine cowpea fields in Northeastern Brazil (PiauÃ?Â, CearÃ?¡, Rio Grande do Norte, ParaÃ?Âba, Pernambuco, Alagoas, Sergipe, Bahia, and Distrito Federal) and partially sequenced. The RNA1 partial sequence, corresponding to the h.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.3.3
- DOI:
- 10.4238/2012.September.3.3
Laronidase for treating mucopolysaccharidosis type I.
Authors: R.P. El Dib, G.M. Pastores
Mucopolysaccharidoses are a group of inherited metabolic diseases caused by the absence or deficiency of the lysosomal enzymes that are needed for breaking down glycosaminoglycans (GAGs). Over time, GAGs collect in cells, blood and connective tissues, and increased amounts are excreted in the urine. The result is permanent and.. Read More»
- Genet. Mol. Res. 6(3):
Cloning and prokaryotic expression of rat homolog of Serpina3n and its expression change during liver regeneration
Authors: G.P. Wang X.S. Zhang Y.H. Li J.L. Zheng C.Z. Tang W.X. Zhang
A strikingly upregulated expressed sequence tag was screened from regenerating rat liver at 8 h in a 0-4-8-12 h short-interval successive partial hepatectomy model from a previous study. In the present study, a full-length open reading frame (ORF) corresponding to this expressed sequence tag was predicted through electronic cloning and was subsequently cl.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.3.6
- DOI:
- 10.4238/2012.September.3.6
Patterns of genetic diversity and population structure of the threatened Houbara and Macqueen�s bustards as revealed by microsatellite markers
Authors: A. Korrida S. Jadallah F. Chbel A. Amin-Alami M. Ahra S. Aggrey
The Houbara bustard (Chlamydotis undulata) is a threatened avian species that is rapidly declining throughout its range, especially in North Africa, Asia and the Canary Islands. We examined the population structure and genetic variation for the three Houbara subspecies C. undulata undulata, C. u. fuertaventurae and C. u. macqueenii. A total of 266 birds from.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.12.4
- DOI:
- 10.4238/2012.September.12.4
Significant interaction of APOE rs4420638 polymorphism with HDL-C and APOA-I levels in coronary heart disease in Han Chinese men
Authors: Y. Huang, H.D. Ye, X. Gao, S. Nie, Q.X. Hong, H.H. Ji, J. Sun, S.J. Zhou, B. Fei, K.Q. Li, J.K. Zhao, Z.P. Wang, M.Q. Xu and S.W. Duan
Apolipoprotein E (APOE) is recognized for its importance in lipoprotein metabolism and cardiovascular disease. We evaluated the association between APOE rs4420638 genotypes and circulating lipid concentrations along with the risk of coronary heart disease (CHD). We conducted a case-control study involving 1508 individuals to investigate the contribution o.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.28.3
- DOI:
- 10.4238/2015.October.28.3
Selection pressures have driven population differentiation of domesticated and wild common carp (Cyprinus carpio L.)
Authors: L.H. Xu C.H. Wang J. Wang Z.J. Dong Y.Q. Ma X.X. Yang
Selection pressures are the principle evolutionary forces for the genetic differentiation of populations. Recent changes in selection pressures on mitochondrial DNA and microsatellite have been described in a wide variety of organisms. The common carp (Cyprinus carpio) has experienced strong selection pressure, in particular artificial selection, during i.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.12.5
- DOI:
- 10.4238/2012.September.12.5
Influence of gossypol acetic acid on the growth of human adenoid cystic carcinoma ACC-M cells and the expression of DNA methyltransferase 1
Authors: Y. Wu, Y.-N. Wei, W.-Y. Yue, W.-F. Chen and S. Fu
We investigated the effects of gossypol acetic acid (GAA) on the proliferation, apoptosis, and expression of DNA methyltransferase 1 (DNMT1) mRNA in human adenoid cystic carcinoma (ACC-M) cells in vitro. The proliferation and apoptosis of ACC-M cells after treatment with different concentrations of GAA were detected using Cell Counting Kit-8 and flow cyto.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.28.6
- DOI:
- 10.4238/2015.October.28.6
Variable expressivity of osteogenesis imperfecta in a Brazilian family due to p.G1079S mutation in the COL1A1 gene
Authors: M.V.D. Moraes M. Milanez B.V.P. Almada V. Sipolatti M.R.G.O. Rebou�§as V.R.R. Nunes A.N. Akel Jr. M. Zatz F.I.V. Errera I.D. Louro F. Paula
Osteogenesis imperfecta (OI) is a Mendelian disease with genetic heterogeneity characterized by bone fragility, recurrent fractures, blue sclerae, and short stature, caused mostly by mutations in COL1A1 or COL1A2 genes, which encode the pro-α1(I) and pro-α2(I) chains of type I collagen, respectively. A Brazilian family that showed variable exp.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.12.7
- DOI:
- 10.4238/2012.September.12.7
Development and characterization of 22 polymorphic microsatellite markers for the balloon flower Platycodon grandiflorum (Campanulaceae)
Authors: J.Y. Song G.-A. Lee M.-S. Yoon K.-H. Ma Y.-M. Choi J.-R. Lee H.-J. Park M.-C. Lee
The balloon flower (Platycodon grandiflorum A. DC.) is a perennial flowering plant of the Campanulaceae family; it is the only member of the genus Platycodon. Information on the genetic diversity of balloon flower populations is of great importance for the conservation and germplasm utilization of this flowering plant. Twenty-two polymorphic microsatellite l.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.12.9
- DOI:
- 10.4238/2012.September.12.9
Identification of quantitative trait loci for blast resistance in BC2F3 and BC2F5 advanced backcross families of rice
Authors: H.A. Rahim M.A.R. Bhuiyan L.S. Lim K.K. Sabu A. Saad M. Azhar R. Wickneswari
Advanced backcross families derived from Oryza sativa cv MR219/O. rufipogon IRGC105491 were utilized for identification of quantitative trait loci (QTL) for blast resistance using simple sequence repeat markers. Two hundred and sixty-one BC2F3 families were used to construct a linkage map, using 87 markers, which covered 2375.2 cM of 12 rice chromosomes, wit.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.12.11
- DOI:
- 10.4238/2012.September.12.11