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Analysis of upland cotton (Gossypium hirsutum) response to Verticillium dahliae inoculation by transcriptome sequencing
Authors: B.X. Shao, Y.L. Zhao, W. Chen, H.M. Wang, Z.J. Guo, H.Y. Gong, X.H. Sang, Y.L. Cui and C.H. Wang
Verticillium wilt is one of the main diseases in cotton (Gossypium hirsutum), severely reduces yield and fiber quality, and is difficult to be controlled effectively. At present, the molecular mechanism that confers resistance to this disease is unclear. Transcriptome sequencing is an important method to detect resistance genes, explore metabolic pathways.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.26.8
- DOI:
- 10.4238/2015.October.26.8
Role of proteinase-activated receptor-1 gene polymorphisms in susceptibility to chronic obstructive pulmonary disease
Authors: C.M. Yun and X.Y. Sang
We conducted a case-control study to investigate the association between PAR1 gene polymorphisms and the development of chronic obstructive pulmonary disease (COPD). A total of 270 patients with COPD and 270 control subjects were consecutively recruited between March 2012 and March 2014. A polymerase chain reaction restriction fragment length polymorphism.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.26.18
- DOI:
- 10.4238/2015.October.26.18
Role of IL-17 gene polymorphisms in the susceptibility to gastric cancer
Authors: W.T. Qi, J.L. Gao and S.S. Zhang
We conducted a study to investigate the role of three IL-17 gene single nucleotide polymorphisms (SNP) (rs2275913G>A, rs3748067C>T, and rs763780 T>C) in the development of gastric cancer. A total of 252 patients with gastric cancer and 252 control subjects were collected between May 2012 and May 2014. The SNP genotyping of IL-17A rs2275913G>A .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.26.33
- DOI:
- 10.4238/2015.October.26.33
Distribution of mitochondrial DNA fragments in the nuclear genome of the honeybee
Authors: W.X. Du and Y.C. Qin
Nuclear mitochondrial pseudogenes (numts), which originated from mitochondrial DNA (mtDNA) insertions in the nuclear genome, have been detected in many species. The distribution of numts in the honeybee nuclear genome has not yet been fully reported. By referring to the whole honeybee mtDNA sequence and to the recent version of the honeybee nuclear genome.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.26.35
- DOI:
- 10.4238/2015.October.26.35
A novel lumazine synthase molecule from Brucella significantly promotes the immune-stimulation effects of antigenic protein
Authors: Z.Q. Du and J.Y. Wang
Brucella, an intracellular parasite that infects some livestock and humans, can damage or destroy the reproductive system of livestock. The syndrome is referred to as brucellosis and often occurs in pastoral areas; it is contagious from livestock to humans. In this study, the intact Brucella suis outer membrane protein 31 (omp31) gene was cloned, recombin.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.26.4
- DOI:
- 10.4238/2015.October.26.4
Differentiation of four strains of Chinese soft-shelled turtle (Pelodiscus sinensis) based on high-resolution melting analysis of single nucleotide polymorphism sites in mitochondrial DNA
Authors: H.Q. Zhang, C. Zhang, X.J. Xu, J.J. Zhu, Z.Y. He and J.Z. Shao
The Chinese soft-shelled turtle (Pelodiscus sinensis) has been one of the most economically important aquatic animals in China for thousands of years, and several breeding strains have been formed. Since the morphological characteristics of some strains are similar, a rapid and accurate molecular method to differentiate between strains is required. In thi.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.26.10
- DOI:
- 10.4238/2015.October.26.10
Association between IL2/IL21 and SH2B3 polymorphisms and risk of celiac disease: a meta-analysis
Authors: C.C. Guo, W.H. Huang, N. Zhang, F. Dong, L.P. Jing, Y. Liu, X.G. Ye, D. Xiao, M.L. Ou, B.H. Zhang, M. Wang, W.K. Liang, G. Yang and C.X. Jing
Celiac disease (CD) is a common autoimmune disorder characterized by heightened immunological response to ingested gluten. Certain gene polymorphisms of IL2/IL21 (rs6822844 and rs6840978) and SH2B3 (rs3184504) may influence susceptibility to CD, although the effects remain unclear. We performed a meta-analysis of the associations between rs6822844, rs6840.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.26.19
- DOI:
- 10.4238/2015.October.26.19
Digital expression analysis of the genes associated with salinity resistance after overexpression of a stress-responsive small GTP-binding RabG protein in peanut
Authors: J.M. Sui, G. Li, G.X. Chen, M.Y. Yu, S.T. Ding, J.S. Wang and L.X. Qiao
The Rab protein family is the largest family of the small GTP-binding proteins. Among them, the RabG genes are known to be responsive to abiotic stresses, but the molecular mechanisms of the stress responses mediated by RabG genes in plants is poorly understood. To investigate the molecular mechanism of AhRabG gene in peanut, .. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019432
- DOI:
- 10.4238/gmr16019432
Microbial diversity in raw milk and traditional fermented dairy products (Hurood cheese and Jueke) from Inner Mongolia, China
Authors: M.L. Gao, H.M. Hou, X.X. Teng, Y.L. Zhu, H.S. Hao and G.L. Zhang
Hurood cheese (HC) and Jueke (Jk) are 2 traditional fermented dairy products produced from raw milk (RM) in the Inner Mongolia region of China. They have a long history of production and consumption. The microbial compositions of RM, HC, and Jk vary greatly, and are influenced by their geographical origins and unique processin.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019451
- DOI:
- 10.4238/gmr16019451
Expression of the stem cell factor in fibroblasts, endothelial cells, and macrophages in periapical tissues in human chronic periapical diseases
Authors: S.Q. Shen, R. Wang and S.G. Huang
Stem cell factor (SCF), an important stem cell cytokine, has multiple functions. Fibroblasts (FBs), mature mast cells, endothelial cells (ECs), and eosinophil granulocytes can produce SCF in the inflammatory process. Therefore, we aimed to observe SCF expression in FBs, ECs, and macrophages (MPs) in periapical tissues in human.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019394
- DOI:
- 10.4238/gmr16019394