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Effect of erythropoietin on mesenchymal stem cell differentiation and secretion in vitro in an acute kidney injury microenvironment
Authors: N.M. Liu, J. Tian, W.W. Wang, G.F. Han, J. Cheng, J. Huang and J.Y. Zhang
We investigated the effect of erythropoietin (EPO) on differentiation and secretion of bone marrow-derived mesenchymal stem cells in an acute kidney injury microenvironment. Acute kidney injury mouse models were prepared. Both renal cortices were then immediately collected to produce the ischemia/reperfusion kidney homogenate supernatant. The morphologica.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.February.28.14
- DOI:
- 10.4238/2013.February.28.14
Maternal MTHFR C677T polymorphism and congenital heart defect risk in the Chinese Han population: a meta-analysis
Authors: K.H. Chen, L.L. Chen, W.G. Li, Y. Fang and G.Y. Huang
Numerous studies have evaluated the association between the maternal C677T polymorphism in the methylenetetrahydrofolate reductase (MTHFR) gene and congenital heart defect (CHD) risk in the Chinese Han population. However, the specific association is still controversial. Six separate studies with 1089 subjects in the Chinese Han population on the relation.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.December.4.8
- DOI:
- 10.4238/2013.December.4.8
Fas/FasL in the immune pathogenesis of severe aplastic anemia
Authors: C.Y. Liu, R. Fu, H.Q. Wang, L.J. Li, H. Liu, J. Guan, T. Wang, W.W. Qi, E.B. Ruan, W. Qu, G.J. Wang, H. Liu, Y.H. Wu, J. Song, L.M. Xing and Z.H. Shao
Fas/FasL protein expression of bone marrow hematopoietic cells was investigated in severe aplastic anemia (SAA) patients. Fas expression was evaluated in CD34+, GlycoA+, CD33+, and CD14+ cells labeled with monoclonal antibodies in newly diagnosed and remission SAA patients along with normal controls. FasL expression was evalua.. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.May.30.3
- DOI:
- http://dx.doi.org/10.4238/2014.May.30.3
RAPD and barcode analyses of groupers of the genus Epinephelus
Authors: K. Noikotr1, A. Chaveerach1, K. Pinthong2, A. Tanomtong1, R. Sudmoon1 and T. Tanee3
The diversity of Epinephelus species was investigated throughout Thailand. Random amplified polymorphic DNA successfully produced 1300 bands that were phylogenetically informative and used to construct cladograms. Values of pairwise genetic similarity (S) within species ranged from 0.65 in E. erythrurus to 0.99 in E. malabaricus. The interspecific values .. Read More»
- Genet. Mol. Res. 12(4):
- 2013.November.18.21
- DOI:
- 10.4238/2013.November.18.21
Mitochondrial and microsatellite DNA analyses showed comparative genetic diversity between parent and offspring populations of Korean black rockfish in a hatchery facility
Authors: H.S. An, J.W. Lee, J.Y. Park, J.I. Myeong and C.M. An
The black rockfish, Sebastes inermis (Sebastidae), is an important commercial fishery resource in Korea. As a preliminary investigation into the effect of artificial reproduction in a hatchery facility, the genetic divergence between parent and offspring populations of black rockfish was accessed using 10 polymorphic nuclear microsatellite DNA loci and a .. Read More»
- Genet. Mol. Res. 12(4):
- 2013.December.9.2
- DOI:
- 10.4238/2013.December.9.2
Association between CASP-8 gene polymorphisms and cancer risk in some Asian population based on a HuGE review and meta-analysis
Authors: Y.J. Zhang, X.P. Zhong, Y. Chen, S.R. Liu, G. Wu and Y.F. Liu
Genetic variation in the CASP-8 gene reportedly can increase cancer susceptibility by regulating tumor cell proliferation and apoptosis. Several studies have investigated this possibility; however, the conclusions remain controversial. We made a Human Genome Epidemiology (HuGE) review and did a meta-analysis to explore the association between CASP-8 gene .. Read More»
- Genet. Mol. Res. 12(4):
- 2013.February.28.3
- DOI:
- 10.4238/2013.February.28.3
Analysis of the genetic variability and structure of Ochlerotatus taeniorhynchus (Diptera: Culicidae) populations from the Colombian Atlantic coast on the basis of random amplified polymorphic DNA markers
Authors: F.J. Bello, N.A. Segura and M. Ruiz-Garcia
Ochlerotatus taeniorhynchus (Diptera: Culicidae) is a mosquito, which is an efficient vector of the virus causing epidemic-epizootic Venezuelan equine encephalitis in Colombia. This study used 9 random amplified polymorphic DNA (RAPD) markers to analyze the mosquito’s genetic variability and genetic structure of 122 spec.. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.May.30.6
- DOI:
- http://dx.doi.org/10.4238/2014.May.30.6
Genetic divergence among accessions of melon from traditional agriculture of the Brazilian Northeast
Authors: F.A.S. Arag�£o, J. Torres Filho, G.H.S. Nunes, M.A. Queir�³z, P.N. Bordallo, G.S.C. Buso, M.A. Ferreira, Z.P. Costa and F. Bezerra Neto
The genetic divergence of 38 melon accessions from traditional agriculture of the Brazilian Northeast and three commercial hybrids were evaluated using fruit descriptors and microsatellite markers. The melon germplasm belongs to the botanic varieties cantalupensis (19), momordica (7), conomon (4), and inodorus (3), and to eight genotypes that were identif.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.December.6.3
- DOI:
- 10.4238/2013.December.6.3
Incorporation of genetic marker information in beef cattle breeding programs
Authors: F.M. Rezende
The availability of molecular marker information has turned out to be an opportunity to improve animal breeding programs, by the inclusion of those effects in the estimation of breeding values. Along this perspective, the aims of present research were to compare genetic evaluation models that assume or not marker effects in the estimation of breeding valu.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.30.1
- DOI:
- 10.4238/2013.October.30.1
Oct4 and Sox2 overexpression improves the proliferation and differentiation of bone mesenchymal stem cells in Xiaomeishan porcine
Authors: Y.X. Fan, C.H. Gu, Y.L. Zhang, B.S. Zhong, L.Z. Wang, Z.R. Zhou,Z.Y. Wang, R.X. Jia, F. Wang
Mesenchymal stem cells derived from bone marrow (BMSCs) are a population of self-renewing multipotent cells that are capable of differentiating into various cellular lineages, and are widely employed in tissue engineering and cell therapy. Recently, clinical research involving BMSCs has become increasingly popular. In order to.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.December.2.5
- DOI:
- 10.4238/2013.December.2.5